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Adacor

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Adacor uses and description

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Adacor - Glucocorticosteroid. Inhibits the function of leukocytes and tissue macrophages. The migration of leukocytes in the area of inflammation. Impair the capacity of macrophages to phagocytosis and the formation of interleukin-1. Contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in the field of inflammation. Decreases capillary permeability due to histamine release. Inhibits activity of fibroblasts and collagen formation.

Inhibits the activity of phospholipase A2 which leads to suppression of the synthesis of prostaglandins and leukotrienes. Suppresses the release of COX (mainly COX-2), which also helps to reduce production of prostaglandins.

Reduces the number of circulating lymphocytes (T-and B-cells), monocytes, eosinophils and basophils as a result of their displacement from the vascular bed to lymphoid tissue, suppresses the formation of antibodies.

hydrocortisone suppresses the release of pituitary ACTH and beta-lipotropin but does not reduce the level of circulating beta-endorphin. Inhibits the secretion of TSH and FSH.

With direct application of the receptacles has a vasoconstrictor effect.

hydrocortisone has a pronounced dose-dependent effect on the metabolism of carbohydrates, proteins and fats. Stimulates gluconeogenesis, promotes the capture of amino acids by the liver and kidneys and increases the activity of enzymes of gluconeogenesis. In the liver of hydrocortisone increases glycogen deposition by stimulating the activity of glycogen synthase and synthesis of glucose from the products of protein metabolism. Increased blood glucose activates the secretion of insulin.

hydrocortisone suppresses the seizure of glucose by fat cells that leads to activation of lipolysis. However, due to increased secretion of insulin is stimulation of lipogenesis which leads to the accumulation of fat.

This medication has catabolic effect in lymphoid and connective tissue, muscle, adipose tissue, skin, bone tissue; to a lesser extent than the mineralocorticoid affects the processes of water and electrolyte metabolism: promotes the excretion of potassium ions and calcium, delay in the body of sodium and water. Osteoporosis and Itsenko-Cushing\'s syndrome are the main factors limiting the long-term therapy of GCS. As a result of catabolic actions may suppress growth in children.

In high doses hydrocortisone may increase the excitability of brain tissue and contributes to lowering the threshold of convulsive readiness. It stimulates the excessive production of hydrochloric acid and pepsin in the stomach that promotes the development of peptic ulcers.

For systems use therapeutic activity of hydrocortisone caused by anti-inflammatory, anti-allergic, immunosuppressive and antiproliferative action. When external and local application the therapeutic activity of hydrocortisone is due to anti-inflammatory, anti-allergic and antiexudative (due to vasoconstrictor effect) action. For anti-inflammatory activity this medicine is 4 times weaker than prednisolone, at mineralocorticoid activity is superior to other GCS.

Indications: skin disorders

Adacor is a glucocorticosteroid. Adacor inhibits the function of leukocytes and tissue macrophages. The migration of leukocytes in the area of inflammation. Impair the capacity of macrophages to phagocytosis and the formation of interleukin-1. Contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in the field of inflammation. Decreases capillary permeability due to histamine release. Inhibits activity of fibroblasts and collagen formation.

Active ingredients: Carvedilol
Unit description, dosagePrice, USD

List of adacor brand and generic drugs

Acridilole (Russian Federation)
Tablets; Oral; Carvedilol 6.25 mg
Alvelol (South Korea)
Anisto (Japan)
Antibloc (Argentina)
Apo-Carve (Czech Republic)
Apo-Carvedilol (Canada)
Tablet; Oral; Carvedilol 12.5 mg
Tablet; Oral; Carvedilol 25 mg
Tablet; Oral; Carvedilol 3.125 mg
Tablet; Oral; Carvedilol 6.25 mg
Apo-Carvedilol 3.125 mg x 100's
Apo-Carvedilol 6.25 mg x 100's
Apo-Carvedilol 12.5 mg x 100's
Apo-Carvedilol 25 mg x 100's
Tablets, Film-Coated; Oral; Carvedilol 3.125 mg
Tablets, Film-Coated; Oral; Carvedilol 6.25 mg
Tablets; Oral; Carvedilol 12.5 mg
Tablets, Film-Coated; Oral; Carvedilol 25 mg
Tablets; Oral; Carvedilol 3.125 mg
Tablets; Oral; Carvedilol 6.25 mg
Tablets; Oral; Carvedilol 25 mg
Arlec
Artione (Japan)
Artist (Japan)
Asiadilol 25
Asiadilol 6.25
Aspen Carvedilol (South Africa)
Atenote (Japan)
Atram (Bulgaria, Czech Republic, Estonia, Latvia, Lithuania, Poland, Romania, Slovakia)
Tablet; Oral; Carvedilol 12.5 mg
Tablet; Oral; Carvedilol 25 mg
Tablet; Oral; Carvedilol 6.25 mg
Tablets; Oral; Carvedilol 12.5 mg
Tablets; Oral; Carvedilol 25 mg
Tablets; Oral; Carvedilol 6.25 mg
Avedol (Poland)
Avernol (Bulgaria)
Bagodilol
Tablet; Oral; Carvedilol 12.5 mg
Tablet; Oral; Carvedilol 25 mg
Tablet; Oral; Carvedilol 3.125 mg
Tablet; Oral; Carvedilol 6.25 mg
Tablets; Oral; Carvedilol 12.5 mg
Tablets; Oral; Carvedilol 25 mg
Tablets; Oral; Carvedilol 3.125 mg

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