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Ademetionine uses and description

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Ademetionine - Heptral belongs to a group of hepatoprotectors with antidepressive activity. Heptral exerts bile-expelling action, possesses detoxification, regeneration, anti oxidative, anti fibrosis and neuroprotective properties. Ademetionine fills the deficiency of Ademetionine and stimulates its production in organism as well. Ademetionine takes part in transmethylation reactions, increases the amount of glutamine in the liver, cysteine and turin in plasma. Ademiteonine also normalizes metabolic processes in the liver.


  • Non-calculous chronic cholecystitis
  • Cholangitis
  • Intrahepatic cholestasis
  • Liver damage caused by toxic substances, alcohol, viruses, drugs(antibiotics, antiviral preparation, tricyclic antidepressant and others)
  • Hepatic steatosis
  • Chronic hepatitis
  • Liver cirrhosis
  • encephalopathy associated with liver failure
  • Depression
  • Abstinent syndrome(including alcoholic).

  • Indications: hepatic cholestasis, hepatic encephalopathy, cirrhosis, depression, alcohol withdrawal syndrome

    Depression and osteoarthritis and liver disorders.

    Active ingredients: Ademetionine
    Unit description, dosagePrice, USD

    List of ademetionine brand and generic drugs

    AdoMet (Thailand)
    Adomet 125 mg x 1,000's
    Denosyl (Australia, New Zealand)
    Donamet (Italy)
    Gumbaral (Germany)
    Heptor (Russian Federation)
    Tablet, Enteric Coated; Oral; 2-S-Adenosyl-Methionine 400 mg
    Heptral (Georgia, Russian Federation)
    Injectable; Injection; Ademetionine Butanedisulfonate 400 mg
    Tablet, Enteric Coated; Oral; Ademetionine Butanedisulfonate 400 mg
    Heptral 400mg - 20 Tablets$ 109.20
    Heptral 400mg/5ml - 5 Vial$ 109.20
    S Amet
    Sameron (South Korea)
    Samyr (Italy)
    Injectable; Injection; Ademetionine Sulfate Tosylate 300 mg
    Injectable; Injection; Ademetionine Sulfate Tosylate 500 mg
    Tablet, Film-Coated; Oral; Ademetionine Sulfate Tosylate 300 mg
    Tablet, Film-Coated; Oral; Ademetionine Sulfate Tosylate 500 mg
    Transmetil (China, Czech Republic, Italy)
    Transmetil 500 mg x 1 Blister x 10 Tablet
    Transmetil 500 mg/5 mL x 1 loï boät ñoâng khoâ vaø 5 mL dung moâi
    Tunik (Argentina)
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