Bactroban - Bactroban, an antibiotic produced from Pseudomonas fluorescens, is structurally unrelated to any other topical or systemic antibiotics. Bactroban is used to treat infection caused by Staphylococcus aureus and beta-hemolytic streptococci including Streptococcus pyogenes. This antibiotic has little, if any, potential for cross-resistance with other antibiotics.
Indication: For the treatment of Staphylococci nasal carriers.
Bactroban is an antibacterial agent. Bactroban is produced by fermentation of the organism Pseudomonas fluorescens. It works against a wide range of gram-positive bacteria such as beta-hemolytic streptococci and methicillin-resistant St. Aureus and certain gram-negative bacteria. Bactroban works by inhibiting isoleucyl transfer-RNA synthetase. This enzyme is needed to produce bacterial proteins. Without the ability to produce proteins bacteria die.
Indications: impetigo caused by Staphylococcus aureus or Streptococcus pyogenes infected eczema folliculitis
Bactroban (Bactroban or Centany) is an antibiotic originally isolated from Pseudomonas fluorescens NCIMB 10586, developed by Beecham.
Bactroban is bacteriostatic at low concentrations and bactericidal at high concentrations. It is used topically and is effective against Gram-positive bacteria, including MRSA. Bactroban is a mixture of several pseudomonic acids, with pseudomonic acid A (PA-A) constituting greater than 90% of the mixture. Also present in Bactroban are pseudomonic acid B with an additional hydroxyl group at C8, pseudomonic acid C with a double bond between C10 and C11, instead of the epoxide of PA-A, and pseudomonic acid D with a double bond at C4` and C5` in the 9-hydroxy-nonanoic acid portion of mupirocin.
Bactroban CREAM is indicated for the treatment of secondarilyinfected traumatic skin lesions (up to 10 cm in length or 100 cm 2
Bacterial skin infections eg, impetigo, furunculosis and folliculitis.
Indications: skin and wound infections
Indications: impetigo, elimination of nasal staphylococci
(mupirocin ointment),2% is indicated for the topical treatment of impetigo due to: Staphylococcus aureus and Streptococcus pyogenes.
As nasal preparations Bactroban used as nasal decongestant
Primary Skin Infections: Impetigo, folliculitis, furunculosis and ecthyma. Secondary Infections: Infected dermatoses eg, infected eczema. Infected traumatic lesions eg, abrasions, insect bites, minor (not requiring hospitalisation) wounds and burns. Prophylaxis: Bactroban may be used to avoid bacterial contamination of small wounds, incisions and other clean lesions, and to prevent infection of abrasions and small cuts and wounds.
Secondary skin infections.
Erdaication of nasal colonisation with staphylococci aureus.