Buspar - Used for: The short-term relief of anxiety symptoms. It may also be used for other conditions as determined by your doctor.
Buspar is an antianxiety agent. It is not known exactly how Buspar works to relieve anxiety. It is believed that it may react with specific chemical receptors in the brain.
Buspar is an anxiolytic drug, a derivative azaspirodecanedione. The mechanism of action is not established. On pharmacological properties this medication does not apply to benzodiazepines or barbiturates. Buspar has a selective anxiolytic effect. This medicine has no anticonvulsant activity, it has no myorelaxant action. It has no sedative effects, especially in low doses.
Buspar has a high affinity for serotonin 5-HT1A-receptors in the neurons of the dorsal suture, and moderate affinity for dopamine D2-receptors in the brain. Buspar has no pronounced affinity for the benzodiazepine receptors, it does not affect the binding of GABA.
Unlike benzodiazepines, the level of spontaneous excitation of noradrenergic cells in locus ceruleus (locus ceruleus) under the action of Buspar increases rather than decreases. These specific differences in the scene due to differences in the development of dependence and tolerance between benzodiazepines and buspirone.
It is believed that Buspar does not cause tolerance, physical or psychological dependence.
Buspar is used in the treatment of generalized anxiety where it has advantages over other antianxiety drugs because it does not cause sedation (drowsiness) and does not cause tolerance or physical dependence. Buspar differs from typical benzodiazepine anxiolytics in that it does not exert anticonvulsant or muscle relaxant effects. It also lacks the prominent sedative effect that is associated with more typical anxiolytics. in vitro preclinical studies have shown that Buspar has a high affinity for serotonin (5-HT) receptors. Buspar has no significant affinity for benzodiazepine receptors and does not affect GABA binding in vitro or in vivo when tested in preclinical models. Buspar has moderate affinity for brain D2-dopamine receptors. Some studies do suggest that Buspar may have indirect effects on other neurotransmitter systems.
Indication: For the management of anxiety disorders or the short-term relief of the symptoms of anxiety, and also as an augmention of SSRI-treatment against depression.
Buspar is an anti-anxiety medicine that affects chemicals in your brain that may become unbalanced and cause anxiety.
Buspar is used to treat symptoms of anxiety, such as fear, tension, irritability, dizziness, pounding heartbeat, and other physical symptoms.
Buspar may also be used for purposes not listed in this medication guide.
It is indicated for the management of anxiety disorders or the short-term relief of the symptoms of anxiety.