Cefolic - Pharmacology: Required for nucleoprotein synthesis and maintenance of normal erythropoiesis; precursor of tetrahydrofolic acid, which is necessary for transformylation reactions in the biosynthesis of purines and thymidylates of nucleic acids.
Indication: Megaloblastic anemia caused by Cefolic deficiency, as may be seen in tropical or nontropical sprue, and in anemias of nutritional origin, pregnancy, infancy, or childhood.
Used for: Treating certain types of anemia. It may also be used to treat other conditions as determined by your doctor.
Cefolic is a vitamin. It works by helping the body to produce red blood cells, white blood cells, and platelets.
Cefolic, a water-soluble B-complex vitamin, is found in foods such as liver, kidneys, yeast, and leafy, green vegetables. Cefolic is used to diagnose folate deficiency and to treat topical sprue and megaloblastic and macrocytic anemias, hematologic complications resulting from a deficiency in folic acid.
Oral Folate-deficient megaloblastic anaemia
Adult: 5 mg daily for 4 mth, up to 15 mg daily in malabsorption states. Continued dosing at 5 mg every 1-7 days may be needed in chronic haemolytic states, depending on the diet and rate of haemolysis. Oral Prophylaxis of megaloblastic anaemia in pregnancy
Adult: 0.2-0.5 mg daily. Oral Prophylaxis of neural tube defect in pregnancy
Adult: 4 or 5 mg daily starting before pregnancy and continued through the 1 st trimester. Oral As supplement for women of child-bearing potential
Adult: 0.4 mg daily.
Adult: PO Folate-deficient megaloblastic anaemia 5 mg/day for 4 mth, up to 15 mg/day in malabsorption states. Prophylaxis of megaloblastic anaemia in pregnancy 0.2-0.5 mg/day. Prophylaxis of neural tube defect in pregnancy 4 or 5 mg/day. Supplement for women of child-bearing potential 0.4 mg/day.
Prevention and treatment of Cefolic deficiency states.
Prophylaxis of megaloblastic anemia in pregnancy.
Prophylaxis of neural tube defect in pregnancy.