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Cefoxitin

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Cefoxitin uses and description

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Cefoxitin - Cefoxitin is in a group of drugs called cephalosporin (SEF a low spor in) antibiotics. It works by fighting bacteria in your body.

Cefoxitin is used to treat many kinds of bacterial infections, including severe or life-threatening forms.

Cefoxitin may also be used for purposes other than those listed in this medication guide.

Cefoxitin is a cephamycin antibiotic often grouped with the second-generation cephalosporins. It is active against a broad range of gram-negative bacteria including anaerobes. The methoxy group in the 7a position provides Cefoxitin with a high degree of stability in the presence of beta-lactamases, both penicillinases and cephalosporinases, of gram-negative bacteria.

Indications:

Adult: IV Prophylaxis of endometritis at caesarean section 2 g as a single dose as soon as the umblical cord is clamped. May be repeated 4 and 8 hr later if needed. IV/IM Susceptible infections 1-2 g 4-8 hrly. Up to 12 g/day for severe infections. Surgical prophylaxis 2 g 30-60 mins pre-op, then 6 hrly, usually for ≤24 hr. IM Uncomplicated UTI 1 g twice daily. Uncomplicated gonorrhoea W/ oral probenecid: 2 g as a single dose.

Intravenous Endometritis (prophylaxis at caesarean section)

Adult: Single 2-g dose to the mother as soon as umbilical cord is clamped. If necessary, dose may be repeated at 4 and 8 hr after initial dose. Intramuscular Uncomplicated UTI

Adult: 1 g bid. Renal impairment: Loading dose: 1-2 g. Maintenance dose: According to CrCl. Haemodialysis patients: Repeat loading dose after each dialysis session. CrCl (ml/min) Dosage Recommendation 30-50 1-2 g every 8-12 hr. 10-29 1-2 g every 12-24 hr. 5-9 0.5-1 g every 12-24 hr. <5 0.5-1 g every 24-48 hr. Intramuscular Uncomplicated gonorrhoea

Adult: Single 2-g dose with probenecid 1 g given orally. Parenteral Treatment and prophylaxis of anaerobic and mixed bacterial infections esp intra-abdominal and pelvic inflammatory disease

Adult: 1-2 g deep IM, slow IV over 3-5 minutes or by intermittent or continuous IV infusion every 4-8 hr. Up to 12 g/day in severe infections.

Child: and neonates: 20-40 mg/kg every 12 hr (neonates up to 1 wk), every 8 hr (neonates 1-4 wk), every 6-8 hr (for child and older infants). Up to 200 mg/kg/day in severe infections. Renal impairment: Loading dose: 1-2 g. Maintenance dose: According to CrCl. Haemodialysis patients: Repeat loading dose after each dialysis session. CrCl (ml/min) Dosage Recommendation 30-50 1-2 g every 8-12 hr. 10-29 1-2 g every 12-24 hr. 5-9 0.5-1 g every 12-24 hr. <5 0.5-1 g every 24-48 hr. Parenteral Prophylaxis for surgical infection

Adult: 2 g IM or IV 30-60 min prior to procedure then every 6 hr, usually not for >24 hr.

Child: and infants: 30-40 mg/kg at the same time intervals as adults. Neonates: 30-40 mg/kg at 8-12 hr intervals.

Parenteral Treatment and prophylaxis of anaerobic and mixed bacterial infections

Adult: 1-2 g deep IM, slow IV over 3-5 minutes or by intermittent or continuous IV infusion every 4-8 hr. Up to 12 g/day in severe infections.

Child: and neonates: 20-40 mg/kg every 12 hr (neonates up to 1 wk), every 8 hr (neonates 1-4 wk), every 6-8 hr (for child and older infants). Up to 200 mg/kg/day in severe infections. Renal impairment: Loading dose: 1-2 g. Maintenance dose: According to CrCl. Haemodialysis patients: Repeat loading dose after each dialysis session. CrCl (ml/min) Dosage Recommendation 30-50 1-2 g every 8-12 hr. 10-29 1-2 g every 12-24 hr. 5-9 0.5-1 g every 12-24 hr. <5 0.5-1 g every 24-48 hr. Intramuscular Uncomplicated urinary tract infections

Adult: 1 g bid. Renal impairment: Loading dose: 1-2 g. Maintenance dose: According to CrCl. Haemodialysis patients: Repeat loading dose after each dialysis session. CrCl (ml/min) Dosage Recommendation 30-50 1-2 g every 8-12 hr. 10-29 1-2 g every 12-24 hr. 5-9 0.5-1 g every 12-24 hr. <5 0.5-1 g every 24-48 hr. Intramuscular Uncomplicated gonorrhoea

Adult: 2 g as a single dose with probenecid 1 g given orally. Parenteral Prophylaxis of surgical infections

Adult: 2 g IM or IV 30-60 min prior to procedure then every 6 hr, usually not for >24 hr.

Child: and infants: 30-40 mg/kg at the same time intervals as adults. Neonates: 30-40 mg/kg at 8-12 hr intervals. Intravenous Prophylaxis of endometritis at caesarean section

Adult: Single 2-g dose to the mother as soon as umbilical cord is clamped. If necessary, dose may be repeated at 4 and 8 hr after initial dose.

Parenteral Treatment and prophylaxis of anaerobic and mixed bacterial infections

Adult: 1-2 g deep IM, slow IV over 3-5 minutes or by intermittent or continuous IV infusion every 4-8 hr. Up to 12 g/day in severe infections.

Child: and neonates: 20-40 mg/kg every 12 hr (neonates up to 1 wk), every 8 hr (neonates 1-4 wk), every 6-8 hr (for child and older infants). Up to 200 mg/kg/day in severe infections. Renal impairment: Loading dose: 1-2 g. Maintenance dose: According to CrCl. Haemodialysis patients: Repeat loading dose after each dialysis session. CrCl (ml/min) Dosage Recommendation 30-50 1-2 g every 8-12 hr. 10-29 1-2 g every 12-24 hr. 5-9 0.5-1 g every 12-24 hr. <5 0.5-1 g every 24-48 hr. Intramuscular Uncomplicated urinary tract infections

Adult: 1 g bid. Renal impairment: Loading dose: 1-2 g. Maintenance dose: According to CrCl. Haemodialysis patients: Repeat loading dose after each dialysis session. CrCl (ml/min) Dosage Recommendation 30-50 1-2 g every 8-12 hr. 10-29 1-2 g every 12-24 hr. 5-9 0.5-1 g every 12-24 hr. <5 0.5-1 g every 24-48 hr. Intramuscular Uncomplicated gonorrhoea

Adult: 2 g as a single dose with probenecid 1 g given orally. Parenteral Prophylaxis of surgical infections

Adult: 2 g IM or IV 30-60 min prior to procedure then every 6 hr, usually not for >24 hr.

Child: and infants: 30-40 mg/kg at the same time intervals as adults. Neonates: 30-40 mg/kg at 8-12 hr intervals. Intravenous Prophylaxis of endometritis at caesarean section

Adult: Single 2-g dose to the mother as soon as umbilical cord is clamped. If necessary, dose may be repeated at 4 and 8 hr after initial dose. Special Populations: Renal impairment: CrCl 30-50 mL/min: 1-2 g 8-12 hrly; 10-29 mL/min: 0.5-1 g 12-24 hrly; <5 mL/min: 0.5-1 g 24-48 hrly. Hemodialysis: Repeat loading dose after each dialysis session.

Active ingredients: Cefoxitin
Unit description, dosagePrice, USD
Injectable; Injection; Cefoxitin Sodium 1 g
Injectable; Injection; Cefoxitin Sodium 2 g
Injectable; Injection; Cefoxitin Sodium 10 g
Cefoxitin 10 gm vial$ 112.25
Cefoxitin 2 gm vial$ 26.28
Cefoxitin 2 gm piggyback bag$ 22.56
Cefoxitin 1 gm vial$ 13.12
Cefoxitin 1 gm piggyback bag$ 12.30

List of cefoxitin brand and generic drugs

Cefoxin (Thailand)
Cefoxin 750 mg x 1's
Cefoxitin ACS Dobfar (United States)
Cefoxitin Antibioticos Brasil (United States)
Cefoxitin APP (United States)
Cefoxitin Baxter (United States)
Cefoxitin Braun (United States)
Cefoxitin Hikma (United States)
Cefoxitin Hospira (United States)
Cefoxitina IPS (Spain)
Cefoxitina Normon (Spain)
Cefoxitina Richet (Argentina)
Cefoxitine
Injectable; Injection; Cefoxitin Sodium 1 g
Injectable; Injection; Cefoxitin Sodium 2 g
Cefoxona (Argentina, Peru)
Cefton
Cefton 50 mg Tablet$ 0.17
Cefxitin (Thailand)
Cefxitin 1 g x 1's
Cexitin (Taiwan)
Cexitin 1 g x 10's
Daliding (China)
DBL Cefoxitin Sodium (Australia, New Zealand)
DBL Cefoxitin Sodium for Injection (Australia, New Zealand)
Destrepen (Greece)
Foxtil
Gamacef
Jeitin (South Korea)
Lofatin (Taiwan)
Lofatin 1 g x 1's
Méfoxin (France)
Mefoxil (Greece)
Mefoxin (Argentina, Bahrain, Cyprus, Egypt, Guyana, Iran, Iraq, Ireland, Italy, Jordan, Kuwait, Lebanon, Luxembourg, Oman, Qatar, Saudi Arabia, Sudan, Syria, Taiwan, United Arab Emirates, United States, Yemen)
Injectable; Injection; Cefoxitin Sodium 1 g
Injectable; Injection; Cefoxitin Sodium 2 g
Injectable; Injection; Cefoxitin Sodium 10 g
Mefoxin in Dextrose 5% in plastic container
Injectable; Injection; Cefoxitin Sodium 20 mg / ml
Injectable; Injection; Cefoxitin Sodium 40 mg / ml
Mefoxin in plastic container
Injectable; Injection; Cefoxitin Sodium 20 mg / ml
Injectable; Injection; Cefoxitin Sodium 40 mg / ml
Mefoxin in Sodium Chloride 0.9% in plastic container
Injectable; Injection; Cefoxitin Sodium 20 mg / ml
Injectable; Injection; Cefoxitin Sodium 40 mg / ml
Mefoxitin (Austria)
Injectable; Injection; Cefoxitin Sodium 1 g
Injectable; Injection; Cefoxitin Sodium 2 g
Metaptyl (Greece)
Panafox (Philippines)
Panafox (vial) 1 g x 10's
Panafox 1 g x 50's$ 19.88
Pluricefo

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