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Chlorprom

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Chlorprom uses and description

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Chlorprom - Used for: Treating certain mental or mood disorders (eg, schizophrenia), the manic phase of manic-depressive disorder, anxiety and restlessness before surgery, the blood disease porphyria, severe behavioral and conduct disorders in children, nausea and vomiting, and severe hiccups. It is also used with other medicines to treat symptoms associated with tetanus. It may also be used for other conditions as determined by your doctor.

Chlorprom is a phenothiazine. The exact way Chlorprom works is not known.

Chlorprom is an anti-psychotic medication in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals in your brain.

Chlorprom is used to treat psychotic disorders such as schizophrenia or manic-depression, and severe behavioral problems in children. It is also used to treat nausea and vomiting, anxiety before surgery, chronic hiccups, acute intermittent porphyria, and symptoms of tetanus.

Chlorprom may also be used for purposes not listed in this medication guide.

Chlorprom is a psychotropic agent indicated for the treatment of schizophrenia. It also exerts sedative and antiemetic activity. Chlorprom has actions at all levels of the central nervous system-primarily at subcortical levels-as well as on multiple organ systems. Chlorprom has strong antiadrenergic and weaker peripheral anticholinergic activity; ganglionic blocking action is relatively slight. It also possesses slight antihistaminic and antiserotonin activity.

Chlorprom is used to treat schizophrenia and bipolar disorder (manic-depressive illness). It helps to quickly relieve symptoms common in schizophrenia and bipolar disorder, such as agitation, distress, distorted thinking and emotional instability. Chlorprom is also used to treat other conditions such as - severe nausea and vomiting in terminal illnesses such as terminal cancer - severe hiccups that cannot be stopped - irritability or aggressiveness in children with autism Chlorprom may also be used for other medical conditions as decided by your doctor.

Chlorprom is used to treat schizophrenia. It helps to relieve symptoms common in schizophrenia, such as distorted thinking and emotional instability. Chlorprom is also used on its own or together with other medicines for the treatment of a dysfunctional mood condition called bipolar disorder. Chlorprom is also used to treat other conditions such as - severe nausea and vomiting - severe hiccups that cannot be stopped - anxiety or nervousness before surgery. - irritability or aggressiveness in children with autism Chlorprom may also be used for other medical conditions as decided by your doctor.

Oral Intractable hiccup

Adult: Initially, 25-50 mg 3-4 times daily for 2-3 days; if unresponsive, may admin 25-50 mg via IM inj. If still necessary, 25-50 mg in 500-1000 ml of normal saline may be given via slow IV infusion.

Child: 1-12 yr: 500 mcg/kg every 4-6 hr. Max: >5 yr: 75 mg daily; 1-5 yr: 40 mg daily.

Elderly: Initially, 1 / 3 -½ the normal adult dose. Oral Psychoses

Adult: 25 mg tid; may be given as a single 75 mg dose at night.

Maintenance: 25-100 mg tid increased to ≥1 g daily as required in psychotic patients.

Child: 1-12 yr: 500 mcg/kg every 4-6 hr. Max: >5 yr: 75 mg daily; 1-5 yr: 40 mg daily.

Elderly: Initially, 1 / 3 -½ the normal adult dose. Intramuscular Psychoses

Adult: 25-50 mg repeated every 6-8 hr. Substitute with oral therapy as soon as possible.

Child: 1-12 yr: 500 mcg/kg every 4-6 hr. Max: >5 yr: 75 mg daily; 1-5 yr: 40 mg daily.

Elderly: Initially, 1 / 3 -½ the normal adult dose. Intramuscular Nausea and vomiting

Adult: Initially, 25 mg via IM inj, followed by 25-50 mg every 3-4 hr until vomiting stops.

Child: 1-12 yr: 500 mcg/kg every 4-6 hr. Max: >5 yr: 75 mg daily; 1-5 yr: 40 mg daily.

Elderly: Initially, 1 / 3 -½ the normal adult dose. Rectal Psychoses

Adult: 100 mg every 6-8 hr as suppositories.

Chlorprom (as Chlorprom hydrochloride, abbreviated CPZ, marketed in the US as Thorazine, as Largactil in Europe) is the oldest typical antipsychotic. The molecular structure is 2-chloro-10-(3-dimethylaminopropyl)-phenothiazine. Chlorprom effectively treats schizophrenia, severe mania in people with bipolar disorder, and uncontrollable hiccups.

Synthesized on December 11, 1950, Chlorprom was the first drug developed with specific antipsychotic action. Its use has been described as the single biggest advance in psychiatric treatment, dramatically improving the prognosis of patients in psychiatric hospitals worldwide. It was the prototype for the phenothiazine class, which later grew to comprise several other agents. It is now used less commonly than the newer atypical antipsychotics such as olanzapine, quetiapine, and risperidone.

Chlorprom works on a variety of receptors in the central nervous system, producing anticholinergic, antidopaminergic, antihistaminic, and antiadrenergic effects. Its anticholinergic properties cause constipation, sedation, hypotension and relieve nausea. It also has anxiolytic (anxiety-relieving) properties. Its antidopaminergic properties can cause extrapyramidal symptoms such as akathisia (restlessness), dystonia, and Parkinsonism.

Chlorprom can cause tardive dyskinesia, which is sometimes irreversible. About one in two thousand patients develop neuroleptic malignant syndrome.[citation needed] It is often administered in acute settings as a syrup, which has a faster onset of action than tablets. Intravenous administration is generally not recommended.

Indications:

Adult: PO Intractable hiccup Initial: 25-50 mg 3-4 times/day for 2-3 days. Psychoses 25 mg 3 times/day.

Maintenance: 25-100 mg 3 times/day, increased to ≥1 g/day if needed in psychotic patients. IM Psychoses 25-50 mg 6-8 hrly. Nausea and vomiting Initial: 25 mg via IM inj, followed by 25-50 mg 3-4 hrly until vomiting stops. Rectal Psychoses As supp: 100 mg 6-8 hrly.

Oral Alleviate intractable hiccup

Adult: Initially, 25-50 mg 3-4 times daily for 2-3 days; if unresponsive, may admin 25-50 mg via IM inj. If still necessary, 25-50 mg in 500-1000 ml of normal saline may be given via slow IV infusion.

Child: 1-12 yr: 500 mcg/kg every 4-6 hr. Max: >5 yr: 75 mg daily; 1-5 yr: 40 mg daily.

Elderly: Initially, 1 / 3 -½ the normal adult dose. Oral Psychiatric conditions

Adult: 25 mg tid; may be given as a single 75 mg dose at night.

Maintenance: 25-100 mg tid increased to ≥1 g daily as required in psychotic patients.

Child: 1-12 yr: 500 mcg/kg every 4-6 hr. Max: >5 yr: 75 mg daily; 1-5 yr: 40 mg daily.

Elderly: Initially, 1 / 3 -½ the normal adult dose. Intramuscular Psychoses

Adult: 25-50 mg repeated every 6-8 hr. Substitute with oral therapy as soon as possible.

Child: 1-12 yr: 500 mcg/kg every 4-6 hr. Max: >5 yr: 75 mg daily; 1-5 yr: 40 mg daily.

Elderly: Initially, 1 / 3 -½ the normal adult dose. Intramuscular Nausea and vomiting associated with surgery

Adult: 25-50 mg every 6-8 hr. Alternatively, 10-25 mg every 4-6 hr via oral admin.

Child: 1-12 yr: 500 mcg/kg every 4-6 hr. Max: >5 yr: 75 mg daily; 1-5 yr: 40 mg daily.

Elderly: Initially, 1 / 3 -½ the normal adult dose. Rectal Psychiatric conditions

Adult: 100 mg every 6-8 hr as suppositories.

Chlorprom (Pfoshen) is used to treat schizophrenia. It helps to relieve symptoms common in schizophrenia, such as distorted thinking and emotional instability. Chlorprom (Pfoshen) is also used on its own or together with other medicines for the treatment of a dysfunctional mood condition called bipolar disorder. Chlorprom (Pfoshen) is also used to treat other conditions such as - severe nausea and vomiting - severe hiccups that cannot be stopped - anxiety or nervousness before surgery. - irritability or aggressiveness in children with autism Chlorprom (Pfoshen) may also be used for other medical conditions as decided by your doctor.

Indications: Schizophrenia and other psychosis, mania and hypomania.

Anxiety, psychomotor agitation, excitement, violent or dangerously impulsive behaviour.

Intractable hiccup.

Nausea and vomiting of terminal illness.

Hypothermia.

Active ingredients: Chlorpromazine
Unit description, dosagePrice, USD
Tablet; Oral; Chlorpromazine Hydrochloride 111.6 mg
Tablet; Oral; Chlorpromazine Hydrochloride 27.9 mg
Tablet; Oral; Chlorpromazine Hydrochloride 55.8 mg

List of chlorprom brand and generic drugs

Chlorpro
Chlorpro 100 mg Tablet$ 0.01
Chlorpromanyl
Drops; Oral; Chlorpromazine Hydrochloride 22.2 mg / ml
Syrup; Oral; Chlorpromazine Hydrochloride 44.5 mg / ml
Chlorpromanyl-20
Chlorpromanyl-40
Chlorpromasit
Chlorpromazine (Bangladesh)
Concentrate; Oral; Chlorpromazine Hydrochloride 100 mg / ml
Concentrate; Oral; Chlorpromazine Hydrochloride 30 mg / ml
Tablet; Oral; Chlorpromazine Hydrochloride 10 mg
Tablet; Oral; Chlorpromazine Hydrochloride 25 mg
Tablet; Oral; Chlorpromazine Hydrochloride 50 mg
Injectable; Injection; Chlorpromazine Hydrochloride 25 mg / ml
Tablet; Oral; Chlorpromazine Hydrochloride 27.9 mg
Tablet; Oral; Chlorpromazine Hydrochloride 100 mg
Tablet; Oral; Chlorpromazine Hydrochloride 200 mg
Injectable; Injection; Chlorpromazine Hydrochloride 27.9 mg / ml
Syrup; Oral; Chlorpromazine Hydrochloride 10 mg / 5 ml
Syrup; Oral; Chlorpromazine Hydrochloride 100 mg / 5 ml
Syrup; Oral; Chlorpromazine Hydrochloride 25 mg / 5 ml
Chlorpromazine 25 mg/ml amp$ 8.04
ChlorproMAZINE HCl 200 mg tablet$ 1.19
Chlorpromazine 200 mg tablet$ 0.02
ChlorproMAZINE HCl 100 mg tablet$ 0.84
ChlorproMAZINE HCl 50 mg tablet$ 0.73
ChlorproMAZINE HCl 25 mg tablet$ 0.55
Chlorpromazine 100 mg tablet$ 0.01
ChlorproMAZINE HCl 10 mg tablet$ 0.37
Chlorpromazine 10 mg tablet$ 0.01
Chlorpromazine 50 mg tablet$ 0.01
Chlorpromazine 25 mg tablet$ 0.01
CHLORPROMAZINE Capsule/ Tablet / 50mg (10 units)$ 0.07
CHLORPROMAZINE Capsule/ Tablet / 25mg (10 units)$ 0.03
CHLORPROMAZINE Capsule/ Tablet / 100mg (10 units)$ 0.15
CHLORPROMAZINE Capsule/ Tablet / 200mg (10 units)$ 0.17
Chlorpromazine 10mg TAB / 10$ 0.07
Chlorpromazine 25mg TAB / 12$ 0.13
Chlorpromazine 50mg TAB / 12$ 0.19
Chlorpromazine 100mg TAB / 12$ 0.26
Chlorpromazine 2.5% INJ / 10x2ml$ 0.39
Chlorpromazine (Pfoshen) 100 mg x 1000's
10 mg x 10's$ 0.07
25 mg x 12's$ 0.13
50 mg x 12's$ 0.19
100 mg x 12's$ 0.26
2.5 % x 2mlx10$ 0.39
Chlorpromazine 50 mg Abbott Injection$ 0.02
Chlorpromazine GPO (Thailand)
Chlorpromazine GPO 250 mg x 500's
Chlorpromazine GPO 50 mg/2 mL x 50 x 1's
Chlorpromazine Hydrochloride Intensol
Chlorpromazine inj
Chlorpromazine inj 25 mg Injection$ 0.16
Chlorpromazine Intensol
Concentrate; Oral; Chlorpromazine Hydrochloride 100 mg / ml

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