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Cinnarizinum

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Cinnarizinum uses and description

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Cinnarizinum - Cinnarizinum is a calcium channel blocker class IV with a predominant effect on the brain vessels, a derivative of piperazine. This medication improves cerebral, coronary and peripheral circulation. Cinnarizinum violates the entrance of calcium ions into vascular smooth muscle cells. This drug lowers the tone of arteriolar smooth muscle, decreases the vasoconstrictor response to biogenic substances (epinephrine, norepinephrine, bradykinin). Cinnarizinum reduces the excitability of the vestibular apparatus. In patients with impaired peripheral circulation Cinnarizinum improves blood flow and potentiates postischemic hyperemia. This medicine increases the resistance of tissue to hypoxia.

Cinnarizinum is an antihistamine and a calcium channel blocker. Histamines mediate a number of activities such as contraction of smooth muscle of the airways and gastrointestinal tract, vasodilatation, cardiac stimulation, secretion of gastric acid, promotion of interleukin release and chemotaxis of eosinophils and mast cells. Competitive antagonists at histamine H1 receptors may be divided into first (sedating) and second (non-sedating) generation agents. Some, such as Cinnarizinum also block muscarinic acetylcholine receptors and are used as anti-emetic agents. Cinnarizinum through its calcium channel blocking ability also inhibits stimulation of the vestibular system.

Indications:

  • Preventing and treating motion sickness
  • Relieving nausea, vomiting, attacks of dizziness or spinning sensations (vertigo) and sensations of ringing or other noise in the ears (tinnitus) associated with Meniere's disease and other middle ear disorders.

  • Oral Peripheral vascular disease

    Adult: 75 mg bid or tid.

    Elderly: Oral Motion sickness

    Adult: 30 mg taken 2 hr before travel and 15 mg every 8 hr during the journey if necessary.

    Child: 5-12 yr: 1 / 2 of adult dose. Oral Cerebrovascular disorders

    Adult: 75 mg 1-3 times daily. Oral Vertigo and vestibular disorders

    Adult: 30 mg tid.

    Child: 5-12 yr: 1 / 2 of adult dose.

    Indications:

    Adult: PO Peripheral vascular diseases 75 mg 2-3 times/day. Motion sickness 30 mg 2 hr before travel and 15 mg 8 hrly during travel if needed. Cerebrovascular disorders 75 mg 1-3 times/day. Vertigo and vestibular disorders 30 mg 3 times/day.

    Oral peripheral vascular disorders

    Adult: 75 mg bid or tid.

    Elderly: Oral Motion sickness

    Adult: 30 mg taken 2 hr before travel and 15 mg every 8 hr during the journey if necessary.

    Child: 5-12 yr: 1 / 2 of adult dose. Oral Cerebrovascular disorders

    Adult: 75 mg 1-3 times daily. Oral Vertigo and other vestibular disturbances, vomiting in Meniere's disease

    Adult: 30 mg tid.

    Child: 5-12 yr: 1 / 2 of adult dose.

    Cinnarizinum Sandoz is a calcium channel blocker class IV with a predominant effect on the brain vessels, a derivative of piperazine. This medication improves cerebral, coronary and peripheral circulation. Cinnarizinum Sandoz violates the entrance of calcium ions into vascular smooth muscle cells. This drug lowers the tone of arteriolar smooth muscle, decreases the vasoconstrictor response to biogenic substances (epinephrine, norepinephrine, bradykinin). Cinnarizinum reduces the excitability of the vestibular apparatus. In patients with impaired peripheral circulation Cinnarizinum Sandoz improves blood flow and potentiates postischemic hyperemia. This medicine increases the resistance of tissue to hypoxia.

    Cinnarizinum Balkanpharma is a calcium channel blocker class IV with a predominant effect on the brain vessels, a derivative of piperazine. This medication improves cerebral, coronary and peripheral circulation. Cinnarizinum Balkanpharma violates the entrance of calcium ions into vascular smooth muscle cells. This drug lowers the tone of arteriolar smooth muscle, decreases the vasoconstrictor response to biogenic substances (epinephrine, norepinephrine, bradykinin). Cinnarizinum reduces the excitability of the vestibular apparatus. In patients with impaired peripheral circulation Cinnarizinum Balkanpharma improves blood flow and potentiates postischemic hyperemia. This medicine increases the resistance of tissue to hypoxia.

    Indications: Improve blood flow to labyrinth and brain stem.

    Vertigo, tinnitus, Meniere disease, loss of memory, motion sickness, cerebrovascular and peripheral vascular disorders.

    Active ingredients: Cinnarizine
    Unit description, dosagePrice, USD

    List of cinnarizinum brand and generic drugs

    Cinnarizine-Eurogenerics (Luxembourg)
    Cinnaron (Estonia, Kenya, Singapore, Sudan, Taiwan, Zimbabwe)
    Cinnaron 25 mg x 50 x 10's
    Cinnaron 25 mg x 500's
    Cinnaron 25 mg x 1000's
    Cinnaron 25 mg x 100 x 10's
    Cinnaron 75 mg x 1000's
    Tablets; Oral; Cinnarizine 25 mg
    Cinnarzine 75
    Cinnasia (India)
    Cinnasia 25mg TAB / 10$ 0.57
    25 mg x 10's$ 0.57
    Cinnatab (Thailand)
    Cinnatab 25 mg x 50 x 10's
    Cinnatab 25 mg x 1,000's
    Cinnaza (Thailand)
    Cinnaza 25 mg x 1,000's
    Cinnazine (Taiwan)
    Cinnazine 25 mg x 1000's
    Cinnazine 25 mg x 100 x 10's
    Cinnipirine
    Cinomyst (Bangladesh)
    Cinon (Portugal)
    Cinrizin (Taiwan)
    Cinrizin 25 mg
    Cinrizine (Thailand)
    Cinrizine 25 mg x 1,000's
    Cintac (India)
    Cintac 25mg TAB / 100$ 8.89
    25 mg x 100's$ 8.89
    Cintigo (India)
    CINTIGO Capsule/ Tablet / 25mg (10 units)$ 0.27
    Cintigo 75mg FC-TAB / 10$ 0.50
    Cintigo 25mg TAB / 10$ 0.26
    25 mg x 10's$ 0.26
    75 mg x 10's$ 0.50
    Tablets, Film-Coated; Oral; Cinnarizine 75 mg
    Tablets; Oral; Cinnarizine 25 mg
    Cintigo 25 mg Tablet$ 0.03
    Cintigo Forte
    Cintigo Forte 75 mg Tablet$ 0.05
    CINTIGO-Forte
    CINTIGO-Forte Capsule/ Tablet / 75mg (10 units)$ 0.53
    Cinvert (India)
    Cinvert 25mg TAB / 10$ 0.19
    Cinvert 75mg TAB / 10$ 0.41
    25 mg x 10's$ 0.19
    75 mg x 10's$ 0.41
    Cinvert 75 mg Tablet$ 0.04
    Cinvert 25 mg Tablet$ 0.02
    CINZAN (India)
    CINZAN Capsule/ Tablet / 25mg (10 units)$ 0.35
    CINZAN Capsule/ Tablet / 75mg (10 units)$ 0.70
    Cinzan 25mg DT-TAB / 10$ 0.37
    Cinzan 75mg DT-TAB / 10$ 0.72

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