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Clopizide-A uses and description

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Clopizide-A - Clopizide-A (USAN), also known as acetylsalicylic acid is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication.

Clopizide-A also has an antiplatelet effect by inhibiting the production of thromboxane, which under normal circumstances binds platelet molecules together to repair damaged blood vessels. This is why Clopizide-A is used in long-term, low doses to prevent heart attacks, strokes, and blood clot formation in people at high risk for developing blood clots. It has also been established that low doses of Clopizide-A may be given immediately after a heart attack to reduce the risk of another heart attack or of the death of cardiac tissue.

The main undesirable side effects of Clopizide-A are gastrointestinal ulcers, stomach bleeding, and tinnitus, especially in higher doses. In children and adolescents, Clopizide-A is no longer used to control flu-like symptoms or the symptoms of chickenpox or other viral illnesses, because of the risk of Reye's syndrome.

Clopizide-A was the first discovered member of the class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs), not all of which are salicylates, although they all have similar effects and most have inhibition of the enzyme cyclooxygenase as their mechanism of action. Today, Clopizide-A is one of the most widely used medications in the world, with an estimated 40,000 tonnes of it being consumed each year. In countries where Clopizide-A is a registered trademark owned by Bayer, the generic term is acetylsalicylic acid (ASA).

Clopidogrel selectively inhibits the binding of adenosine diphosphate to its platelet receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation. Biotransformation of Clopidogrel is necessary to produce inhibition of platelet aggregation, but an active metabolite responsible for the activity of the drug has not been isolated. Clopidogrel also inhibits platelet aggregation induced by agonists other than ADP by blocking the amplification of platelet activation by released ADP. Clopidogrel does not inhibit phosphodiesterase activity. Clopidogrel acts by irreversibly modifying the platelet ADP receptor. Consequently, platelets exposed to Clopidogrel are affected for the remainder of their lifespan. Dose dependent inhibition of platelet aggregation can be seen 2 hours after single oral doses of Clopidogrel bisulfate. Repeated doses of 75 mg Clopidogrel bisulfate per day inhibit ADP-induced platelet aggregation on the first day, and inhibition reaches steady state between Day 3 and Day 7. At steady state, the average inhibition level observed with a dose of 75 mg Clopidogrel bisulfate per day was between 40% and 60%. Platelet aggregation and bleeding time gradually return to baseline values after treatment is discontinued, generally in about 5 days.

Clopidogrel is an oral antiplatelet agent (thienopyridine class) to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease. It is marketed by Bristol-Myers Squibb and Sanofi-Aventis under the trade name Plavix, by Sun Pharmaceuticals under the trade name Clopilet, by Ranbaxy Laboratories under the trade name Ceruvin, and under the name "Clavix" by Intas Pharmaceuticals. It works by irreversibly inhibiting a receptor called P2Y12. Adverse effects include hemorrhage.

Active ingredients: Aspirin
Unit description, dosagePrice, USD
Clopizide-A Aspirin 75 mg, Clopidogrel 75mg, TAB / 100
Clopizide-A Aspirin 75 mg, Clopidogrel 150mg. TAB / 100
Clopizide-A Aspirin 75mg, Clopidogrel 75mg TAB / 100
Clopizide-A Aspirin 75mg, Clopidogrel150mg TAB / 100
Clopizide-A Aspirin 75 mg, Clopidogrel 75mg. TAB / 100

List of clopizide-a brand and generic drugs

Clopivas-AP (India)
10's$ 0.49
Clopod A
Clopod A 75+150 Tablet$ 0.14
Cloprez A
Cloprez A 75+75 Tablet$ 0.11
Cloprez A 75+150 Tablet$ 0.13
Clouds 150 (India)
Clouds 150 Aspirin 150 mg, Clopidogrel 75mg. TAB / 10$ 0.46
Clouds 150 Aspirin 75 mg, Clopidogrel 75mg. TAB / 10$ 0.44
Clouds 150 Aspirin 150mg, Clopidogrel75mg TAB / 10$ 0.46
Clouds 150 Aspirin 75mg, Clopidogrel 75mg TAB / 10$ 0.44
10's$ 0.44
Coated Aspirin (Canada)
Tablet, Enteric Coated; Oral; Aspirin 325 mg
Tablet, Enteric Coated; Oral; Aspirin 80 mg
Tablets, Enteric Coated; Oral; Aspirin 325 mg
Tablets, Enteric Coated; Oral; Aspirin 80 mg
Coated Daily Low-Dose ASA
Tablet, Delayed Release; Oral; Aspirin 81 mg
Tablets, Delayed Release; Oral; Aspirin 81 mg
Coco Scalp (New Zealand)
Codalgina Retard
Colsprin (India)
Colsprin 100mg TAB / 14$ 0.47
100 mg x 14's$ 0.47
Tablets; Oral; Aspirin 100 mg
Colsprin 100 mg Tablet$ 0.00
Colsprin 325+97.5+32.5 Tablet$ 0.00
Colsprin 195+650+65 Tablet$ 0.01
Comfort Meider (Taiwan)
Comfort Meider 650 mg x 1000's
Comfort Meider 500 mg x 1000's
Complatt (India)
Complatt Clopidogrel 75 mg, Aspirin 75mg. TAB / 10$ 1.37
10's$ 1.24
Complatt Clopidogrel 75 mg, Aspirin 75mg TAB / 10$ 1.24
Complatt 75+75 Capsule$ 0.12
Complatt Forte (India)
Complatt Forte Clopidogrel 75 mg, Aspirin 150mg. TAB / 10$ 1.37
10's$ 1.37
Complatt Forte 75+150 Tablet$ 0.14
Contrheuma Retard
Contrheuma SR
Tablet, Sustained Release; Oral; Aspirin
Tablets, Sustained Release; Oral; Aspirin
Cor (Philippines)
Tablet, Enteric Coated; Oral; Esomeprazole 20 mg
Tablet, Enteric Coated; Oral; Esomeprazole 40 mg
Cor-30 (Philippines)
Cor-30 30 mg x 560's$ 16.52
Cor-As (Serbia)

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