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Cloranfenicol

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Cloranfenicol uses and description

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Cloranfenicol - Pharmacology: Interferes with or inhibits microbial protein synthesis.

Indication: Treatment of infections caused by susceptible strains of specific microorganisms; serious systemic infections for which less potentially dangerous drugs are ineffective or contraindicated.

Cloranfenicol is a broad-spectrum antibiotic that was derived from the bacterium Streptomyces venezuelae and is now produced synthetically. Cloranfenicol is effective against a wide variety of microorganisms, but due to serious side-effects (e.g., damage to the bone marrow, including aplastic anemia) in humans, it is usually reserved for the treatment of serious and life-threatening infections (e.g., typhoid fever). Cloranfenicol is bacteriostatic but may be bactericidal in high concentrations or when used against highly susceptible organisms. Cloranfenicol stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis.

Oral Bacterial meningitis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Brain abscess

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Granuloma inguinale

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Anthrax

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Listeriosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Gas gangrene

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Whipple's disease

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe systemic infections with Camphylobacter fetus

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Infections caused by H. influenzae

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Ehrlichiosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe gastroenteritis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe melioidosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Plague

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Psittacosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Q fever

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Anaerobic bacterial infections

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Tularaemia

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Ophthalmic Ocular infections

Adult: Instill 1 drop of a 0.5% solution every 2 hr. Increase dosage interval upon improvement. To continue treatment for at least 48 hr after complete healing. Reduce dose once symptoms are controlled or apply a 1% ointment 3-4 times daily. Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Otic/Aural Otitis externa

Adult: Instill 2-3 drops of a 5% solution into the ear bid-tid. Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required.

Cloranfenicol is a bacteriostatic antimicrobial. It is considered a prototypical broad-spectrum antibiotic, alongside the tetracyclines.

Cloranfenicol is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any indication in developed nations, although it is sometimes used topically for eye infections; nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use. In low-income countries, Cloranfenicol is still widely used because it is exceedingly inexpensive and readily available.

The most serious adverse effect associated with Cloranfenicol treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and aplastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.

Oral Bacterial meningitis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Anaerobic infections

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Brain abscess

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Granuloma inguinale

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Plague and tularaemia

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Anthrax

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Listeriosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Gas gangrenes

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Whipple's disease

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe systemic infections with Camphylobacter fetus

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Infections due to H. influenzae

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Ehrlichiosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe gastroenteritis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe melioidosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Psittacosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Q fever

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Ophthalmic Eye infections

Adult: Instill 1 drop of a 0.5% solution every 2 hr. Increase dosage interval upon improvement. To continue treatment for at least 48 hr after complete healing. Reduce dose once symptoms are controlled or apply a 1% ointment 3-4 times daily. Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Otic/Aural otitis externa

Adult: Instill 2-3 drops of a 5% solution into the ear bid-tid. Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required.

Indications:

Adult: PO Susceptible infections 50 mg/kg/day in 4 divided doses, may increase to 100 mg/kg/day in more severe infections. Ophth Ocular infections As 0.5% soln: Instill 1 drop 2 hrly, then adjust dosage interval upon improvement. Otic Otitis externa As 5% soln: Instill 2-3 drops 2-3 times/day.

Cloranfenicol is indicated for the topical treatment of infections due to micro-organisms sensitive to the anti-infective.

Indications: Enteric fever (Typhoid and Para typhoid).

H.

Influenzae meningitis.

Anaerobic infections, intraocular infections, urinary tract infections, conjunctivitis, external ear infections.

Corneal ulcer, bacterial conjunctivitis, trachoma, ocular infections.

Otitis externa, chronic otitis media.

Pre and post antral or mastoid surgery.

Active ingredients: Chloramphenicol
Unit description, dosagePrice, USD
Solution; Ophthalmic; Chloramphenicol 0.5%
Solution; Oral; Chloramphenicol 125 mg / 5 ml

List of cloranfenicol brand and generic drugs

Cloranfenico
Cloranfenicol Ariston (Brazil)
Cloranfenicol Colmed (Colombia)
Cloranfenicol Fabra (Argentina)
Cloranfenicol L.CH. (Chile)
Cloranfenicol LCH (Chile)
Cloranfenicol Made (Portugal)
Cloranfenicol MK (Colombia, Ecuador)
Cloranfenicol Nicolich (Chile)
Ointment; Ophthalmic; Chloramphenicol 1%
Solution; Ophthalmic; Chloramphenicol 0.5%
Cloranfenicol Richet (Argentina)
Cloranfenil
Cloranmicron
Cloraxin (Vietnam)
Cloraxin 0.4 % x 10 mL
Cloraxin 0.5 % x 10 mL
Cloraxin vieân ñaët (Vietnam)
Cloraxin Tablet ñaët 125 mg x 1 Blister 10 Tablet
Cloraxin Tablet ñaët 125 mg x 1 loï 20 Tablet
Cloraxin XNDP 2-9 (Vietnam)
Cloraxin XNDP 2-9 250 mg x 10 Tablet
Clorazin
Clordil
Capsule; Oral; Chloramphenicol
Clorfenil
Clorin (Peru)
Clornicol (Vietnam)
Clornicol 0.4 % x 1 chai 10 mL
Clorocetin
Clorocetin 5 ml Drop$ 0.20
Clorocid (Vietnam)
Clorocid 0.25 g 250 mg x 1 chai 500 Tablet
Clorocid 4‰ 0.4 % x 1 loï 8 mL
Clorocid 4‰ 0.4 % x 1 loï 10 mL
Clorocil (Portugal)
Clorocin
Clorocin 250 mg Capsule$ 0.05
Clorocin 50 ml Suspension$ 0.06
Clorocyn
Clorofenicina
Clorofunon
Cloromisan (Peru)
Cloroptic (Peru)
Clorosintex
Cloroxit (Vietnam)
Cloroxit 1 g x 1 loï
Cloz-CB (India)
Cloz-CB Chloramphenicol 5 % w/v,Beclomethasone dipropionate0.025 % w/v, Clotrimazole 1 %w/v, Lignocaine 2 % w/v. EAR-DPS / 7.5ml$ 0.65
7.5ml$ 0.65
Cloz-CB Chloramphenicol 5 % w/v,beclomethasone dipropionate0.025 % w/v, clotrimazole 1 %w/v, lignocaine 2 % w/v. EAR DPS / 7.5ml$ 0.65
Cluvatin (Philippines)
Cluvatin 250 mg x 100's
Cogenate

Show all Cloranfenicol generic names
 
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