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DURALYN - CR

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DURALYN - CR uses and description

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DURALYN - CR - DURALYN - CR is a bronchodilator. It works by relaxing muscles in the lungs and chest, and makes the lungs less sensitive to allergens and other causes of bronchospasm.

DURALYN - CR is used to treat the symptoms of asthma, bronchitis and emphysema.

DURALYN - CR may also be used for other purposes not listed in this medication guide.

Pharmacology: Relaxes bronchial smooth muscle and stimulates central respiratory drive.

Indication: Prevention or treatment of reversible bronchospasm associated with asthma or COPD.

DURALYN - CR, an xanthine derivative chemically similar to caffeine and theobromine, is used to treat asthma and bronchospasm. DURALYN - CR has two distinct actions in the airways of patients with reversible (asthmatic) obstruction; smooth muscle relaxation (i.e., bronchodilation) and suppression of the response of the airways to stimuli (i.e., non-bronchodilator prophylactic effects).

Oral Acute bronchospasm

Adult: As conventional tablet: 5 mg/kg every 6-8 hr.

Child: As conventional tablet: 5 mg/kg every 4-6 hr. Hepatic impairment: Dose adjustment needed. Oral Chronic bronchospasm

Adult: As conventional dosage form: 300-1000 mg in divided doses, every 6-8 hr daily. As modified-release preparations: 175-500 mg every 12 hr. Rate of absorption of modified released preparations varies for different brands.

Child: <2 yr: Not recommended; 2-6 yr: ¼ the adult dose; 20-35 kg (about 6-12 yr old): ½ the adult dose. Rate of absorption of modified released preparations varies for different brands. Hepatic impairment: Dose adjustment needed. Oral Apnoea in infants

Child: Initial dose in neonates: ≤24 days: 1 mg/kg every 12 hr; >24 days: 1.5 mg/kg every 12 hr. Full-term infants: initial daily dosage calculated based on formula, given in 3-4 divided doses: daily dose (mg/kg) = (0.2 X age in wk) + 5.0. If loading dose is needed, 5 mg/kg (or in those already on theophylline, 1 mg/kg for each 2 mcg/ml increase in serum-theophylline concentration). Intravenous Severe bronchospasm

Adult: Patients who are not taking DURALYN - CR or other xanthine medication: 4-5 mg/kg as loading dose by IV infusion over 20-30 minutes followed by

Maintenance: 0.4 mg/kg/hr.

Child: Patients who are not taking DURALYN - CR or other xanthine medication: 4-5 mg/kg as loading dose by IV infusion over 20-30 minutes, followed by maintenance dose: 1-9 yr: 0.8 mg/kg/hr; >9 yr: 0.6-0.7 mg/kg/hr. Hepatic impairment: Dose adjustment needed. Special Populations: Reduce dose in patients with cor pulmonale, heart failure, liver disease and in the elderly. Increase maintenance dose for smokers.

DURALYN - CR is used to treat asthma. DURALYN - CR is known as a "bronchodilator", which literally means "open airways". DURALYN - CR helps to treat your asthma or chest illness by relaxing the airways in your lungs. DURALYN - CR relieves chest tightness, wheezing and cough so that you can breathe more easily.

DURALYN - CR, also known as dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as COPD or asthma under a variety of brand names. Due to its numerous side-effects, these drugs are now rarely administered for clinical use. As a member of the xanthine family, it bears structural and pharmacological similarity to caffeine. It is naturally found in tea, although in trace amounts (~1 mg/L), significantly less than therapeutic doses. It is found also in cocoa beans. Amounts as high as 3.7 mg/g have been reported in Criollo cocoa beans.

Indications:

Adult: PO Acute bronchospasm 5 mg/kg 6-8 hrly. Chronic bronchospasm 300-1,000 mg in divided doses 6-8 hrly. Extended release 175-500 mg 12 hrly. IV Severe bronchospasm Patients who are not taking DURALYN - CR or other xanthine medication: Loading dose: 4-5 mg/kg via infusion, then 0.4 mg/kg/hr.

Indications: Reversible airway obstructive diseases.

Active ingredients: Theophylline
Unit description, dosagePrice, USD
DURALYN - CR Modified Release Capsule/ Tablet / 400mg (10 units)$ 0.98
DURALYN - CR Modified Release Capsule/ Tablet / 200mg (10 units)$ 0.54

List of duralyn - cr brand and generic drugs

DURALYN-CR (India)
Duralyn-CR 400 mg x 10 x 10's
Duraphyl
Tablet, Extended Release; Oral; Theophylline 100 mg
Tablet, Extended Release; Oral; Theophylline 200 mg
Tablet, Extended Release; Oral; Theophylline 300 mg
Duraphyllin CR
Capsule, Controlled Release; Oral; Theophylline 150 mg
Capsule, Controlled Release; Oral; Theophylline 400 mg
Duraphyllin Retard
Capsule, Controlled Release; Oral; Theophylline 150 mg
Capsule, Controlled Release; Oral; Theophylline 250 mg
Capsule, Controlled Release; Oral; Theophylline 400 mg
Durofilin (Serbia)
Durofilin retard (Bosnia & Herzegowina)
Egifilin (Hungary)
Elixex
Elixicon
Suspension; Oral; Theophylline 100 mg / 5 ml
Elixifilin (Spain)
Elixine (Chile)
Capsule, Prolonged Release; Oral; Theophylline 125 mg
Capsule, Prolonged Release; Oral; Theophylline 250 mg
Capsule, Prolonged Release; Oral; Theophylline 300 mg
Solution; Oral; Theophylline 80 mg / 15 ml
Elixir De Theophylline
Elixir; Oral; Theophylline 80 mg / 15 ml
Elixofilina
Elixomin
Elixir; Oral; Theophylline 80 mg / 15 ml
Elixophyllin (United States)
Capsule; Oral; Theophylline 100 mg
Capsule; Oral; Theophylline 200 mg
Elixir; Oral; Theophylline 80 mg / 15 ml
Elixophyllin SR
Capsule, Extended Release; Oral; Theophylline 125 mg
Capsule, Extended Release; Oral; Theophylline 250 mg
Elixophylline (USA)
473 milliliter in 1 bottle
Etheophyl
Etipramid (China)
Eufilina (Portugal, Spain)
Eufilina Venosa (Spain)
Euphyllin 200
Euphyllin CR retard (Poland)
Euphyllin long (Poland)
Euphyllin N
Injectable; Injection; Theophylline 20 mg / ml
Euphyllin Retard (Austria, Bahrain, Bangladesh, Egypt, Indonesia, Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Qatar, Saudi Arabia, South Africa, Sri Lanka, Taiwan, United Arab Emirates)
Euphyllin Retard 250 mg x 100's$ 28.61
Euphyllin Retard Mite 125 mg x 100's$ 16.66
Euphyllin retard N (Switzerland)
Tablet, Film-Coated; Oral; Theophylline Anhydrous 250 mg
Euphyllin SR
Tablet, Sustained Release; Oral; Theophylline
Euphyllina
Euphylline L.A. (France)
Capsule, Prolonged Release; Oral; Theophylline Anhydrous 100 mg

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