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Damaton

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Damaton uses and description

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Damaton - Damaton changes the shape of red blood cells in your blood. This makes it easier for these blood cells to fit into small arteries (blood vessels).

Damaton is used to improve blood flow. Improved blood flow helps to reduce leg cramps and other symptoms of vascular disease (disease related to veins and arteries).

Damaton may also be used for purposes other than those listed in this medication guide.

Pharmacology: Improves blood flow by decreasing blood viscosity.

Indication: Intermittent claudication on basis of chronic occlusive arterial disease of limbs.

Unlabeled Uses

Treatment of psychopathological symptoms in patients with cerebrovascular insufficiency; treatment of diabetic angiopathies and neuropathies, transient ischemic attacks, leg ulcers, sickle cell thalassemias, strokes, high-altitude sickness, asthenozoospermia, acute and chronic hearing disorders, severe idiopathic recurrent aphthous stomatitis, eye circulation disorders, and Raynaud phenomenon.

Damaton, a synthetic dimethylxanthine derivative structurally related to theophylline and caffeine, is used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

Oral Peripheral vascular disease

Adult: As modified-release formulation: 400 mg tid (normally for at least 8 wk), may reduce to 400 mg bid if GI or CNS adverse effects occur. Renal impairment: Moderate impairment (CrCl about 60 ml/min): 400 mg bid; severe impairment (CrCl about 20 ml/min): 400 mg once daily; may reduce further to 400 mg once every other day if needed. Hepatic impairment: Dose reduction may be needed in severe impairment. Special Populations: Adjust dose in patients with impaired renal function or severe hepatic impairment.

Oral peripheral vascular disorders

Adult: As modified-release formulation: 400 mg tid (normally for at least 8 wk), reduce to 400 mg bid if adverse effects occur. CrCl (ml/min) Dosage Recommendation <30 30-50% dose depending on individual tolerance. Hepatic impairment: Severe impairment: Reduce dose.

Indications: Peripheral vascular disease.

This medication is used to improve the symptoms of a certain blood flow problem in the legs/arms (intermittent claudication due to occlusive artery disease). Damaton can decrease the muscle aching/pain/cramps during exercise, including walking, that occur with intermittent claudication. Damaton belongs to a class of drugs known as hemorrheologic agents. It works by helping blood flow more easily through narrowed arteries. This increases the amount of oxygen that can be delivered by the blood when the muscles need more (such as during exercise) thereby increasing walking distance and duration.

Active ingredients: Pentoxifylline
Unit description, dosagePrice, USD

List of damaton brand and generic drugs

Claudicat Retard
Tablet, Retard; Oral; Pentoxifylline 600 mg
DanKe (China)
Dartelin (Bosnia & Herzegowina, Poland, Slovenia)
De Bao Xing (China)
De Luo Wei (China)
Dian Ke Shu (China)
Difusil (Peru)
Dimethyloxohexylxanthine
Dinostral
Tablet, Retard; Oral; Pentoxifylline 400 mg
Dospan Pento
Dospan-Pento (Argentina)
Duplat (Mexico)
Dragee; Oral; Pentoxifylline 400 mg
DUPLAT Injection / 10mg per 10ml (10ml units)$ 1.52
DUPLAT Injection / 50mg per 50ml (50ml units)$ 5.74
Duplat 10mg x 10mL INJ / 10ml$ 1.52
Duplat 50mg x 5mL INJ / 50ml$ 5.74
10 mg x 10 mL x 10ml$ 1.52
50 mg x 5 mL x 50ml$ 5.74
Duplat 50 mg Injection$ 0.11
Duplat 10 mg Injection$ 0.15
Durapental (Germany, Peru)
Tablet, Coated; Oral; Pentoxifylline 400 mg
Durapental Retard
Tablet, Retard; Oral; Pentoxifylline 600 mg
Elastab
Elorgan (Spain)
Endopentoksas (Lithuania)
Eshieton (Taiwan)
Eshieton 100 mg
Eurotofi
Fei Ke Wei Kang (China)
Fixoten (Mexico)
Tablet, Extended Release; Oral; Pentoxifylline 400 mg
Flexital (Myanmar, Russian Federation)
Injectable; Injection; Pentoxifylline 20 mg / ml
Tablet, Film-Coated; Oral; Pentoxifylline 100 mg
Tablet, Retard; Oral; Pentoxifylline 400 mg
FLEXITAL Capsule/ Tablet / 400mg (10 units)$ 0.55
FLEXITAL Injection / 20mg per ml (15ml units)$ 0.10
FLEXITAL Capsule/ Tablet / 200mg (10 units)$ 0.37
Flexital 400mg TAB / 10$ 0.44
Flexital 20mg/mL INJ / 15ml$ 0.10
400 mg x 10's$ 0.44
20 mg x 1 mL x 15ml$ 0.10
Flexital 400 mg Tablet$ 0.05
Flexital 300 mg Injection$ 0.01
Flexital CR (Thailand)
Flexital CR 400 mg x 5 x 10's

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