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Defrijet

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Defrijet uses and description

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Defrijet - Defrijet binds to iron and removes it from the blood stream.

Defrijet is used to treat iron overload caused by blood transfusions in adults and children at least 2 years old.

Defrijet may also be used for purposes not listed in this medication guide.

Pharmacology: Orally active chelating agent that has a high affinity for binding with iron.

Indication: Treatment of chronic iron overload caused by blood transfusions (transfusional hemosiderosis) in patients 2 yr of age and older.

Defrijet is an orally active chelator that is selective for iron (as Fe3+). It is a tridentate ligand that binds iron with high affinity in a 2:1 ratio. Although Defrijet has very low affinity for zinc and copper there are variable decreases in the serum concentration of these trace metals after the administration of deferasirox. The clinical significance of these decreases is uncertain.

Defrijet is used to remove excess iron in your body. Iron may build up in your body after repeated blood transfusions. Too much iron in your body can damage your vital organs, such as the heart and the liver.

Oral Chronic iron overload

Adult: 20 mg/kg once daily. Adjust dose every 3-6 mth when needed. Max: 30 mg/kg daily.

Child: ≥2 yr: 20 mg/kg once daily. Max: 30 mg/kg daily.

Indications: Chronic iron overload.

Active ingredients: Deferasirox
Unit description, dosagePrice, USD
Defrijet 250 mg Tablet$ 0.45
Defrijet 500 mg Tablet$ 0.74

List of defrijet brand and generic drugs

ASUNRA (India)
400 mg x 6's$ 14.87
Asunra 400mg DT-TAB / 6$ 14.87
Deferasirox (Argentina, Australia, Austria, Belgium, Bulgaria, Canada, Croatia (Hrvatska), Denmark, Finland, France, Germany, Greece, Hong Kong, Hungary, Indonesia, Ireland, Israel, Italy, Mexico, Netherlands, New Zealand, Norway, Oman, Peru, Slovakia, Slovenia, South Africa, Spain, Sweden, Switzerland, Taiwan, Turkey, United Kingdom, United States, Venezuela)
Exjade 500 mg tablet$ 78.61
Exjade 250 mg tablet$ 39.30
Exjade 125 mg tablet$ 19.65
Exjade (Argentina, Australia, Austria, Belgium, Bulgaria, Canada, Croatia (Hrvatska), Denmark, Finland, France, Germany, Greece, Hong Kong, Hungary, Indonesia, Ireland, Israel, Italy, Mexico, Netherlands, New Zealand, Norway, Oman, Peru, Slovakia, Slovenia, South Africa, Spain, Sweden, Switzerland, Taiwan, Turkey, United Kingdom, United States, Venezuela)
Tablet, Dispersible; Oral; Deferasirox 125 mg
Tablet, Dispersible; Oral; Deferasirox 250 mg
Tablet, Dispersible; Oral; Deferasirox 500 mg
30 tablet in 1 bottle
Exjade 250 mg x 4 x 7's
Exjade 125 mg x 28's$ 253.02
Exjade 250 mg x 28's$ 506.05
Exjade 500 mg x 28's
Exjade 125 mg x 4 x 7's$ 204.00
Exjade 500 mg x 4 x 7's$ 809.13
EXJADE 125 mg, 250mg, 500mg dispersible tablets (United Kingdom)
 
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