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Dexbrompheniramine

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Dexbrompheniramine uses and description

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Dexbrompheniramine - In allergic reactions an allergen interacts with and cross-links surface IgE antibodies on mast cells and basophils. Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell-degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil. Once released, histamine can react with local or widespread tissues through histamine receptors. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Dexbrompheniramine is a histamine H1 antagonist (or more correctly, an inverse histamine agonist) of the alkylamine class. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

Oral Allergic conditions (urticaria, rhinitis, conjunctivitis)

Adult: In combination with decongestant, pseudoephedrine: 2 mg up to 4 times daily.

Child: >6 yr: In combination with pseudoephedrine, 1 mg up to 4 times daily.

Indications: Allergic conditions.

Active ingredients: Dexbrompheniramine
Unit description, dosagePrice, USD
Ala-hist ir 2 mg tablet$ 0.82

List of dexbrompheniramine brand and generic drugs

Disomer
Syrup; Oral; Dexbrompheniramine Maleate 2 mg / 5 ml
Tablet; Oral; Dexbrompheniramine Maleate 2 mg
 
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