Dexona - Dexona is a potent synthetic member of the glucocorticoid class of steroid hormones. It acts as an anti-inflammatory and immunosuppressant. Its potency is about 20-30 times that of hydrocortisone and 4-5 times of prednisone.
Dexona helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Dexona may also be used to prevent organ transplant rejection after a transplant. Dexona may be used for other purposes as decided by your doctor. Dexona belongs to a group of medicines called steroids.
Anti-inflammatory,As a screening test for Cushing’s syndrome,Acute exacerbations in multiple sclerosis,Unresponsive shock,Bacterial meningitis,Prophylaxis of nausea and vomiting associated with cytotoxic therapy,Cerebral oedema caused by malignancy,Ocular inflammation,Inflammatory joint diseases.
Dexona is a glucocorticosteroid. This medication Inhibits the function of leukocytes and tissue macrophages. Dexona restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Dexona decreases capillary permeability caused by histamine release. This medicine inhibits the activity of fibroblasts and collagen formation.
Dexona inhibits the activity of phospholipase A2, which leads to suppression of the synthesis of prostaglandins and leukotrienes.
With direct application to the vessels this drug has a vasoconstrictor effect.
Dexona has a pronounced dose-dependent effect on the metabolism of carbohydrates, proteins and fats.
In high doses Dexona may increase the excitability of brain tissue and contributes to lowering the threshold of convulsive readiness.
With systemic use of therapeutic activity of Dexona is due to anti-inflammatory, antiallergic, immunosuppressive and antiproliferative action.
For external and local use of therapeutic activity of Dexona is due to anti-inflammatory, antiallergic and antiexudative (due to vasoconstrictor effect) effect.
Indications: Replacement therapy: Adrenal insufficiency.
Nonendocrine diseases: Rheumatoid arthirits.
Osteoarthritis, Acute gouty arthirits.
Collagen diseases e.
systemic lupus erythematosus, polyarteritis nodosa, dermatomyositis, nephritic syndrome, glomerulonephritis and related diseases.
Severe allergic reactions e.
anaphylaxis, angioneurotic edema, urticaria and serum sickness and related diseases.
Autoimmune diseases e.
haemolytic anaemia, idiopathic thrombocytopenic purpura, active chronic hepatitis and related diseases.
Other lung diseases e.
pulmonary edema, accelerate lung maturation and surfactant production in the foetus and prevent respiratory distress syndrome at birth.
Infective diseases e.
severe forms of tuberculosis, severe lepra reaction, certain forms of bacterial meningitis and Pneumocystis carinii pneumonia with hypoxia in AIDS patients along with proper antibiotic c
Indications: Orally used for bacterial diarrhoeas and dysentery.
Preparation of bowel before surgery.
Topically for infected wound, ulcers, burn, external ear infections, conjunctivitis.