Diclofen - NSAIDs, a derivative of phenylacetic acid, Diclofen has a pronounced anti-inflammatory, analgesic and mild antipyretic effect. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. Analgesic effect is due to two mechanisms: peripheral (indirectly, through suppression of prostaglandin synthesis) and central (due to inhibition of prostaglandin synthesis in the central and peripheral nervous system).
Inhibits synthesis of proteoglycan in cartilage.
In rheumatic diseases, Diclofen reduces joint pain at rest and in motion, as well as morning stiffness and swelling of the joints, helps to increase range of motion; reduces post-traumatic and postoperative pain, and inflammatory edema.
Inhibits platelet aggregation. With prolonged use has a desensitizing effect.
When used topically in ophthalmology reduces swelling and pain in inflammatory processes non-infectious etiology.
Diclofen (Yuan Chou) helps relieve pain and inflammation.
Diclofen (H.C.) helps relieve pain and inflammation.
Diclofen (H.S.) helps relieve pain and inflammation.
Diclofen (Kojar) helps relieve pain and inflammation.
Indications: gout, inflammation, musculoskeletal and joint disorders, pain
Indications: musculoskeletal, joint, and peri-articular disorders
Indications: inflammation, musculoskeletal, joint, peri-articular, and soft-tissue disorders, pain
Bursitis,Tendinitis,Pain and inflammation associated with musculoskeletal and joint disorders,Acute gout,Dysmenorrhoea,Migraine,Postoperative pain,Prophylaxis of postoperative pain,Strains,Tendinitis,Renal colic,Prophylaxis of intra-operative miosis,Post-photorefractive keratectomy pain,Seasonal allergic conjunctivitis,Control of inflammation after argon laser trabeculoplasty,Inflammation and discomfort after strabismus surgery,Pain after accidental trauma,Local symptomatic relief of pain and inflammation,Osteoarthritis.
Diclofen (marketed as Voltaren and under a number of other trade names, see below) is a non-steroidal anti-inflammatory drug (NSAID) taken to reduce inflammation and as an analgesic reducing pain in conditions such as arthritis or acute injury. It can also be used to reduce menstrual pain, dysmenorrhea. The name is derived from its chemical name: 2-(2,6-dichloranilino)phenylacetic acid.
In the United Kingdom, India, and the United States, it may be supplied as either the sodium or potassium salt, in China most often as the sodium salt, while in some other countries only as the potassium salt. Diclofen is available as a generic drug in a number of formulations. Over the counter (OTC) use is approved in some countries for minor aches and pains and fever associated with common infections.
Indications: Rheumatoid arthritis, osteoarthritis, low back pain, ankylosing spondylitis, gout.
Acute musculo skeletal disorders, periarthritis (Frozen shoulder) tendinitis, tenosynovitis, bursitis, sprains and dislocations.
Painful post-operative conditions.
Pain following dental surgery.
Painful inflammatory conditions in gynaecology.
Inhibition of intraoperative miosis and postoperative inflammation in cataract surgery.