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Digoxina

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Digoxina uses and description

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Digoxina - Used for: Treating heart failure or slowing the heart rate in patients with chronic atrial fibrillation, a type of abnormal heart rhythm. It may also be used for other conditions as determined by your doctor.

Digoxina is a digitalis glycoside. It works by increasing the force of contraction of the heart and slowing heart rate.

Pharmacology: Increases force and velocity of myocardial systolic contraction (positive inotropic action), slows heart rate, decreases conduction velocity through AV node, and decreases the degree of activation of the sympathetic nervous system and renin-angiotensin system. All actions are mediated through effects on sodium-potassium ATPase.

Indication: Treatment of mild to moderate heart failure; control of ventricular response rate in chronic atrial fibrillation.

Digoxina, a cardiac glycoside similar to digitoxin, is used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation.

Digoxina, also known as digitalis, is a purified cardiac glycoside extracted from the foxglove plant, Digitalis lanata.[2] Its corresponding aglycone is digoxigenin, and its acetyl derivative is acetyldigoxin. Digoxina is widely used in the treatment of various heart conditions, namely atrial fibrillation, atrial flutter and sometimes heart failure that cannot be controlled by other medication. Digoxina preparations are commonly marketed under the trade names Lanoxin, Digitek, and Lanoxicaps. It is also available as a 0.05mg/mL oral solution and 0.25mg/mL or 0.5mg/mL injectable solution.

Digoxina is used to treat heart failure and certain types of heart disease in which the heart rhythm is irregular, such as atrial fibrillation and atrial flutter. Digoxina works by giving better control over your heart rate and rhythm. It also improves the contraction power of your heart.

Oral Heart failure

Adult: Rapid digitalisation: Loading dose of 0.75-1.5 mg during the first 24-hr period as a single dose or in divided doses every 6 hr for less urgent or greater risk cases. For mild heart failure: Loading dose may not be required, 250 mcg 1-2 times daily. For patients with normal renal function, steady-state plasma concentrations are usually achieved in about 7 days. Usual

Maintenance: 125-250 mcg daily but may range from 62.5-500 mcg daily.

Child: Neonate <1.5 kg: Initial: 25 mcg/kg/day in 3 divided doses for 24 hr, then 4-6 mcg/kg/day in 1-2 divided doses; neonate 1.5-2.5 kg: Initial: 30 mcg/kg/day in 3 divided doses for 24 hr, then 4-6 mcg/kg/day in 1-2 divided doses; Neonate >2.5 kg and child 1 mth-2 yr: Initial: 45 mcg/kg/day in 3 divided doses for 24 hr, then 10 mcg/kg/day in 1-2 divided doses. 2-5 yr: Initial: 35 mcg/kg/day in 3 divided doses for 24 hr, then 10 mcg/kg/day in 1-2 divided doses. 5-10 yr: Initial: 25 mcg/kg/day (max: 750 mcg/day) in 3 divided doses for 24 hr, then 6 mcg/kg/day (max: 250 mcg/day) in 1-2 divided doses. 10-18 yr: Initial: 0.75-1.5 mg/day in 3 divided doses for 24 hr, then 62.5-750 mcg/day in 1-2 divided doses. Reduce doses if patient has been given cardiac glycoside in the preceding 2 wk.

Elderly: Lower doses are given. Renal impairment: Dosage reductions may be needed. Oral Supraventricular arrhythmias

Adult: Rapid digitalisation: Loading dose of 0.75-1.5 mg during the first 24-hr period as a single dose or in divided doses every 6 hr for less urgent or greater risk cases. For mild heart failure: Loading dose may not be required, 250 mcg 1-2 times daily. For patients with normal renal function, steady-state plasma concentrations are usually achieved in about 7 days. Usual

Maintenance: 125-250 mcg daily but may range from 62.5-500 mcg daily.

Child: Neonate <1.5 kg: Initial: 25 mcg/kg/day in 3 divided doses for 24 hr, then 4-6 mcg/kg/day in 1-2 divided doses; neonate 1.5-2.5 kg: Initial: 30 mcg/kg/day in 3 divided doses for 24 hr, then 4-6 mcg/kg/day in 1-2 divided doses; Neonate >2.5 kg and child 1 mth-2 yr: Initial: 45 mcg/kg/day in 3 divided doses for 24 hr, then 10 mcg/kg/day in 1-2 divided doses. 2-5 yr: Initial: 35 mcg/kg/day in 3 divided doses for 24 hr, then 10 mcg/kg/day in 1-2 divided doses. 5-10 yr: Initial: 25 mcg/kg/day (max: 750 mcg/day) in 3 divided doses for 24 hr, then 6 mcg/kg/day (max: 250 mcg/day) in 1-2 divided doses. 10-18 yr: Initial: 0.75-1.5 mg/day in 3 divided doses for 24 hr, then 62.5-750 mcg/day in 1-2 divided doses. Reduce doses if patient has been given cardiac glycoside in the preceding 2 wk.

Elderly: Lower doses are given. Renal impairment: Dosage reductions may be needed. Intravenous Emergency heart failure

Adult: For patients who have not received cardiac glycosides in the previous 2 wk. 0.5-1 mg by IV infusion as a single dose over at least 2 hr or in divided doses with each dose given over 10-20 minutes. Maintenance dose is usually given orally. Renal impairment: Dosage reductions may be needed. Reconstitution: Admin undiluted or diluted with a 4-fold or greater volume of Sterile Water for Injection, 0.9% Sodium Chloride Injection, or 5% Dextrose Injection. Incompatibility: Using less than a 4-fold volume of diluent could lead to precipitation of the digoxin.

Treatment of low output congestive heart failure with atrial fibrillation. The action of Digoxina to impair atrioventricular conduction is employed in the management of atrial flutter, atrial fibrillation and paroxysmal atrial tachycardia.

Oral Supraventricular arrhythmias, atrial fibrillation and heart failure

Adult: Rapid digitalisation: Loading dose of 0.75-1.5 mg during the first 24-hr period as a single dose or in divided doses given every 6 hr for less urgent or greater risk cases. For milder cases: Loading dose is not required. 250 mcg once or twice daily.

Maintenance:, 125-250 mcg daily but may also range from 62.5-500 mcg daily. High doses should be given in divided doses.

Elderly: Lower doses are given. Renal impairment: Dosage reductions may be needed. Intravenous Emergency heart failure

Adult: If the patient has not received cardiac glycosides in the previous 2 wk. 0.5-1 mg by IV infusion as a single dose over at least 2 hr or in divided doses, each given over 10-20 minutes. Maintenance dose is usually given orally. Renal impairment: Dosage reductions may be needed. Reconstitution: Admin undiluted or diluted with a 4-fold or greater volume of Sterile Water for Injection, 0.9% Sodium Chloride Injection, or 5% Dextrose Injection. Incompatibility: Using less than a 4-fold volume of diluent could lead to precipitation of the digoxin.

Indications:

Adult: PO Heart failure ; Supraventricular arrhythmias Rapid digitalisation: Loading dose: 0.75-1.5 mg in the 1st 24 hr. Slow digitilisation: 250 mcg 1-2 times/day. Uusal

Maintenance: 125-250 mcg/day. IV Emergency heart failure For patients who have not received cardiac glycosides in the previous 2 wk: 0.5-1 mg via infusion as a single dose or in divided doses.

Maintenance: Usually via oral admin.

Congestive Heart Failure : Primarily in the case of low output failure Digoxina is recommended both to achieve and to maintain compensated condition particularly when heart failure is associated with atrial fibrillation or auricular flutter. Atrial fibrillation; atrial flutter ; paroxysmal supraventricular tachycardia.

Indications: Congestive heart failure, cardiac tachyarrhythmias (Paroxysmal supraventricular tachycardia, atrial flutter and fibrillation.

Active ingredients: Digoxin
Unit description, dosagePrice, USD
Tablet; Oral; Digoxin 0.25 mg
Injectable; Injection; Digoxin 0.025%
Tablet; Oral; Digoxin 0.0625 mg
Tablet; Oral; Digoxin 0.125 mg
Tablet; Oral; Digoxin 0.1875 mg
Tablet; Oral; Digoxin 0.375 mg
Tablet; Oral; Digoxin 0.5 mg

List of digoxina brand and generic drugs

Digoxin-Zori (Israel)
Tablet; Oral; Digoxin 0.25 mg
Digoxina Andromaco (Chile)
Digoxina Biol (Argentina)
Digoxina Kern Pharma (Spain)
Digoxina L.CH. (Chile)
Digoxina Lafedar (Argentina)
Digoxina Larjan (Argentina)
Digoxina Mintlab (Chile)
Digoxina Rider (Chile)
Digoxina Teofarma (Spain)
Digoxine Nativelle (France, Luxembourg, Tunisia, Turkey)
Injectable; Injection; Digoxin 0.25 mg / ml
Solution; Oral; Digoxin 0.05 mg / ml
Tablet; Oral; Digoxin 0.25 mg
Digoxine Nativelle 0.25 mg x 30 Tablet
Digoxine Nativelle 5 mcg/0.1 mL x 60 mL
Digoxine Nativelle 0.5 mg/2 mL x 2 mL x 6 oáng
Digoxine Nativelle 0.05 mg/1 mL x 1 mL x 6 oáng
Digoxine Navtivelle
Injectable; Injection; Digoxin 0.25 mg / ml
Solution; Oral; Digoxin 0.05 mg / ml
Tablet; Oral; Digoxin 0.25 mg
Digoxine NIHFI (Tunisia)
Digoxine Sine (China)
Dilacor (Bulgaria, Serbia, Tunisia)
Dilanacin
Tablet; Oral; Digoxin
Dilanacin 0.25
Dimecip
Dixina
Dogoxine
Dokim
Dynamos
Eudigox (Italy)
Fargoxin (Indonesia)
Fargoxin 0.25 mg x 10 x 10's$ 2.55
Fargoxin (amp) 0.5 mg/2 mL x 5's$ 14.28
GEOXIN (India)
0.5 mg x 2 mL x 2mlx5$ 0.93
0.25 mg x 50's$ 0.93
Geoxin 0.5mg x 2mL INJ / 2mlx5$ 0.93
Geoxin 0.25mg TAB / 50$ 0.93
Geoxin 0.25 mg Tablet$ 0.02
Geoxin 0.5 mg Injection$ 0.09
Grexin (Thailand)
Grexin 250 mcg x 1,000's
Halfdigoxin (Japan)
Hemigoxine Nativelle (France)
Tablet; Oral; Digoxin 0.125 mg

Show all Digoxina generic names
 
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