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Dislipor

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Dislipor uses and description

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Dislipor - Dislipor is a lipid-lowering drugs of the statin group. An inhibition of HMG-CoA reductase leads to a series of sequential reactions that result in reduced intracellular cholesterol content and it is a compensatory increase in activity of LDL receptors and thus accelerate the catabolism of LDL cholesterol.

The lipid-lowering effect of statins is associated with lower levels of total cholesterol by LDL-C. The reduction in LDL cholesterol is dose-dependent and is not linear, but exponential. The inhibitory effect of Dislipor on HMG-CoA reductase by about 70% determined by the activity of its circulating metabolites.

Statins do not affect the activity of lipoprotein lipase and hepatic, no significant effect on the synthesis and catabolism of free fatty acids, so their effect on triglycerides and again vicariously through their main effects on reducing LDL-C.

In addition to lipid-lowering actions, statins have beneficial effects in endothelial dysfunction (pre-clinical sign of early atherosclerosis) in the vascular wall, the state of atheroma, improves blood rheology, have antioxidant, antiproliferative properties.

Dislipor lowers cholesterol levels in patients with homozygous familial hypercholesterolemia, which is usually not amenable to therapy with lipid-lowering agents.

Indications: hypercholesterolaemia

Reduce the amount of cholesterol in blood. Slow the progression of atherosclerosis (hardening) of the arteries that nourish the heart, causing so-called coronary heart disease (CHD). Reduce the development of new atherosclerosis. It is indicated:As an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels and to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Fredrickson Types IIa and IIb);As an adjunct to diet for the treatment of patients with elevated serum TG levels (Fredrickson Type IV);.For the treatment of patients with primary dysbetalipoproteinemia (Fredrickson Type III) who do not respond adequately to diet;.To reduce total-C and LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments (e.g., LDL apheresis) or if such treatments are unavailable;.As an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys and postmenarchal girls, 10 to 17 years of age, with heterozygous familial hypercholesterolemia if after an adequate trial of diet therapy the following findings are present: a. LDL-C remains ? 190 mg/dL orb. LDL-C remains ? 160 mg/dL and: there is a positive family history of premature cardiovascular disease ortwo or more other CVD risk factors are present in the pediatric patient.

Active ingredients: Atorvastatin
Unit description, dosagePrice, USD
Tablet, Film-Coated; Oral; Atorvastatin Calcium 10 mg
Tablet, Film-Coated; Oral; Atorvastatin Calcium 20 mg
Tablets, Film-Coated; Oral; Atorvastatin Calcium 10 mg
Tablets, Film-Coated; Oral; Atorvastatin Calcium 20 mg

List of dislipor brand and generic drugs

Dislipat (Hungary)
Divastin (Bangladesh)
Divator (Turkey)
Doss-Medichrom (Greece)
Dotstat
Dotstat 20 mg Tablet$ 0.17
Dotstat 5 mg Tablet$ 0.09
Dotstat 10 mg Tablet$ 0.13
Drutova
Drutova 10 mg Tablet$ 0.12
Durastat
Durastat 10 mg Tablet$ 0.10
Durastat ASP
Durastat ASP 75+10 Capsule$ 0.03
Durastat EZ
Durastat EZ 10+10 Tablet$ 0.17
DYSLIP (India)
5 mg x 10's$ 0.69
10 mg x 10's$ 1.35
20 mg x 10's$ 2.34
Dyslip 5mg TAB / 10$ 0.69
Dyslip 10mg TAB / 10$ 1.35
Dyslip 20mg TAB / 10$ 2.34
Dyslip 10 mg Tablet$ 0.14
Dyslip 5 mg Tablet$ 0.07
Dyslip 20 mg Tablet$ 0.23
Dyslip EZ
Dyslip EZ 10+10 Tablet$ 0.22
Dysliptin (India)
Dysliptin 5mg TAB / 10$ 0.69
Dysliptin 10mg TAB / 10$ 1.35
Dysliptin 20mg TAB / 10$ 2.34
Dysliptin 40mg TAB / 10$ 3.23
5 mg x 10's$ 0.69
10 mg x 10's$ 1.35
20 mg x 10's$ 2.34
40 mg x 10's$ 3.23
Dysliptin 40 mg Tablet$ 0.32
Dysliptin 20 mg Tablet$ 0.23
Dysliptin 10 mg Tablet$ 0.14
Dysliptin 5 mg Tablet$ 0.07
Dysliptin EZ
Dysliptin EZ 10+10 Tablet$ 0.22
Dysliptin TG
Dysliptin TG 200+10 Tablet$ 0.21
Dystorva
Dystorva 10 mg Tablet$ 0.09
Ecosprin -AV
Ecosprin -AV Atorvastatin 10mg, Aspirin75mg CAP / 10$ 1.39
ECOSTAT (India)
ECOSTAT Capsule/ Tablet / 20mg (10 units)$ 2.94
ECOSTAT Capsule/ Tablet / 10mg (10 units)$ 1.65
Ecostat Atorvastatin 10 mg, Ezetimibe10 mg. TAB / 10$ 1.65
Ecostat Atorvastatin 20 mg, Ezetimibe10 mg. TAB / 10$ 2.94
10's$ 2.94

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