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Duloxetine

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Duloxetine uses and description

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Duloxetine - Duloxetine is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). Duloxetine affects chemicals in the brain that may become unbalanced and cause depression.

Duloxetine is used to treat major depressive disorder and general anxiety disorder.

Duloxetine is also used to treat fibromyalgia (a chronic pain disorder), or chronic muscle or joint pain (such as low back pain and osteoarthritis pain).

Duloxetine is also used to treat pain caused by nerve damage in people with diabetes (diabetic neuropathy).

Duloxetine may also be used for purposes not listed in this medication guide.

Duloxetine is in a class of medications called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) and primarily targets major depressive disorders (MDD) and stress urinary incontinence (SUI). Duloxetine is also used to treat pain and tingling caused by diabetic neuropathy (damage to nerves that can develop in people who have diabetes). Known also as LY248686, it is a potent dual inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and norepinephrine (NE) reuptake, possessing comparable affinities in binding to NE and 5-HT transport sites. Interestingly, its behavior contrasts to most other dual-reuptake inhibitors. Furthermore, duloxentine lacks affinity for monoamine receptors within the central nervous system.

Duloxetine is used to treat depression and anxiety. It is also used to treat nerve pain in people who have diabetes. Duloxetine has also been used to control the bladder in women who have urinary incontinence.

Oral Depression

Adult: 20-30 mg bid or 60 mg once daily. Max: 60 mg daily. Renal impairment: CrCl ≥30 ml/min: No adjustment needed. Avoid use in severe impairment. Oral Diabetic neuropathy

Adult: 60 mg once daily. Max: 120 mg daily. Renal impairment: CrCl ≥30 ml/min: No adjustment needed. Avoid use in severe impairment. Oral Moderate to severe stress urinary incontinence in women

Adult: 40 mg bid. Renal impairment: CrCl ≥30 ml/min: No adjustment needed. Avoid use in severe impairment. Special Populations: In renal impairment, lower starting dose and consider gradual increase in dose.

Indications:

Adult: PO Depression 20-30 mg twice daily. Max: 60 mg/day. Diabetic neuropathy 60 mg once daily. Max: 120 mg/day. Moderate to severe stress incontinence in women 40 mg twice daily.

Active ingredients: Duloxetine
Unit description, dosagePrice, USD
Capsule, Gastro-Resistant; Oral; Domperidone 30 mg
Capsule, Gastro-Resistant; Oral; Domperidone 60 mg
Cymbalta 30 mg Enteric Coated Capsule$ 5.38
Cymbalta 60 mg Enteric Coated Capsule$ 5.38
Cymbalta 30 mg capsule$ 5.18
Cymbalta 60 mg capsule$ 5.18
Cymbalta 20 mg Enteric Coated Capsule$ 4.64
Cymbalta 20 mg capsule$ 4.62
Duloxetine (generic) 60mg - 28 Tablets$ 199.95
Duloxetine (generic) 60mg - 56 Tablets$ 349.95

List of duloxetine brand and generic drugs

Duloxen (Bangladesh)
Duloxetine Boehringer (Latvia, Lithuania)
Duloxmo
Duloxmo 20 mg Tablet$ 0.08
Duloxmo 30 mg Tablet$ 0.11
Duloxyl
Duloxyl 20 mg Capsule$ 0.10
Dultin
Dultin 20 mg Tablet$ 0.07
Dultin 60 mg Tablet$ 0.21
Dultin 40 mg Tablet$ 0.14
Dultin 30 mg Tablet$ 0.11
Dulx (India)
Dulx 20mg TAB / 10$ 0.83
Dulx 30mg TAB / 10$ 1.30
Dulx 40mg TAB / 10$ 1.65
Dulx 60mg TAB / 10$ 2.41
20 mg x 10's$ 0.83
30 mg x 10's$ 1.30
40 mg x 10's$ 1.65
60 mg x 10's$ 2.41
Dulx 40 mg Tablet$ 0.16
Dulx 30 mg Tablet$ 0.13
Dulx 20 mg Tablet$ 0.08
Dulx 60 mg Tablet$ 0.24
Dumore (India)
Dumore 20mg CAP / 10$ 0.81
Dumore 30mg CAP / 10$ 1.20
Dumore 60mg CAP / 10$ 2.22
20 mg x 10's$ 0.81
30 mg x 10's$ 1.20
60 mg x 10's$ 2.22
Dumore 20 mg Capsule$ 0.10
Dumore 60 mg Capsule$ 0.22
Dumore 30 mg Tablet$ 0.12
Dupact (India)
Dupact 20mg CAP / 10$ 0.28
Dupact 30mg CAP / 10$ 1.14
Dupact 60mg CAP / 10$ 2.20
20 mg x 10's$ 0.28
30 mg x 10's$ 1.14
60 mg x 10's$ 2.20
Dupact 20 mg Capsule$ 0.09
Dupact 60 mg Capsule$ 0.22
Dupact 30 mg Capsule$ 0.13
Dureep (India)
Dureep 20mg CAP / 10$ 0.85
20 mg x 10's$ 0.85
Dureep 20 mg Capsule$ 0.09
Dutin (India)
Dutin 20mg CAP / 10$ 0.83

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