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EpiPen Jr

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EpiPen Jr uses and description

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EpiPen Jr - Pharmacology: Stimulates alpha and beta receptors (alpha receptors at high doses; beta- receptors at moderate doses) within the sympathetic nervous system. Relaxes smooth muscle of bronchi and iris, and is an antagonist of histamine.

Indication: EpiPen Jr 1:1,000 injection

Relief of respiratory distress due to bronchospasm; to provide rapid relief of hypersensitivity reactions to drugs and other allergens (eg, anaphylactic reactions to drugs, animal serums, insect stings); to prolong the action of local and regional anesthetics; restore cardiac rhythm in cardiac arrest due to various causes; treatment of mucosal congestion of hay fever, rhinitis, and acute sinusitis; relieve bronchial asthmatic paroxysms; symptomatic relief of serum sickness, urticaria, angioneurotic edema; for relaxation of uterine musculature and to inhibit uterine contractions; EpiPen Jr injection can be used as a hemostatic agent; in syncope due to complete heart block or carotid sinus hypersensitivity; for resuscitation in cardiac arrest following anesthetic accidents; used in open-angle glaucoma.

EpiPen Jr 1:1,000 (auto-injector) and 1:2,000 (auto-injector), Prefilled syringe

Emergency treatment of allergic reactions (type I) including anaphylaxis to insect stings (eg, bees, fire ants, hornets, yellow jackets, wasps) and biting insects (eg, mosquitoes), allergen immunotherapy, foods, drugs, diagnostic testing substances (eg, radiocontrast media), and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis. The auto-injectors and prefilled syringes are intended for immediate self-administration in patients who are at increased risk for anaphylaxis, including individuals with a history of anaphylactic reactions. Auto-injectors and prefilled syringes are for immediate use and are not a substitute for immediate medical attention.

EpiPen Jr 1:10,000 injection

Treatment and prophylaxis of cardiac arrest in the absence of ventricular fibrillation and attacks of transitory atrioventricular heart block with syncopal seizures; to stimulate the heart in syncope due to complete heart block or carotid sinus hypersensitivity; for resuscitation in cardiac arrest following anesthetic accidents; in cardiopulmonary resuscitation, intracardiac puncture and intramyocardial injection of EpiPen Jr may be effective when external cardiac compression and attempts to restore the circulation by electrical defibrillation or use of pacemaker fail; seldom used as a vasopressor except in the treatment of anaphylactic shock and under certain conditions in insulin shock.

Nasal solution

Nasal decongestant.

Oral inhalation

Temporary relief of shortness of breath, tightness of chest, and wheezing due to bronchial asthma; temporary relief of bronchial asthma; easing breathing for asthma patients by reducing spasms of bronchial muscles.

Unlabeled Uses

Endoscopic injection for the management of acute lower GI bleeding; overdosage of beta-blockers, calcium channel blockers, and tricyclic antidepressants (and other sodium channel blockers); symptomatic bradycardia or hypotension that did not respond to atropine and transcutaneous pacing.

EpiPen Jr is indicated for intravenous injection in treatment of acute hypersensitivity, treatment of acute asthmatic attacks to relieve bronchospasm, and treatment and prophylaxis of cardiac arrest and attacks of transitory atrioventricular heart block with syncopal seizures (Stokes-Adams Syndrome). The actions of EpiPen Jr resemble the effects of stimulation of adrenergic nerves. To a variable degree it acts on both alpha and beta receptor sites of sympathetic effector cells. Its most prominent actions are on the beta receptors of the heart, vascular and other smooth muscle. When given by rapid intravenous injection, it produces a rapid rise in blood pressure, mainly systolic, by (1) direct stimulation of cardiac muscle which increases the strength of ventricular contraction, (2) increasing the heart rate and (3) constriction of the arterioles in the skin, mucosa and splanchnic areas of the circulation. When given by slow intravenous injection, EpiPen Jr usually produces only a moderate rise in systolic and a fall in diastolic pressure. Although some increase in pulse pressure occurs, there is usually no great elevation in mean blood pressure. Accordingly, the compensatory reflex mechanisms that come into play with a pronounced increase in blood pressure do not antagonize the direct cardiac actions of EpiPen Jr as much as with catecholamines that have a predominant action on alpha receptors.

Indications:

Adult: IV Advanced cardiac life support As 1:10,000 soln: 1 mg, repeat every 2-3 mins if needed. Anaphylactic shock As 1:10,000 soln: 5 mL infused slowly until a response is achieved. IM Anaphylactic shock As 1:1,000 soln: 0.5 mL, repeat every 5 mins as needed. IM/SC Acute asthma As 1:1,000 soln: 0.3-0.5 mL. Ophth Open-angle glaucoma ; Ocular HTN As 0.5, 1 or 2% soln: Instill 1-2 times/day. Inhalation Acute asthma Per metered dose from pressurised aerosols contains 160-275 mcg of epinephrine: 1-2 inhalations, repeat 3 hr later if needed.

Inhalation Acute asthma

Adult: Spray: Aqueous solution with an adrenaline content equivalent to 1:100. Pressurised aerosols delivering metered doses equivalent to approximately 160-275 mcg: 1-2 inhalations, may repeat after 3 hr if necessary. Parenteral Acute asthma

Adult: As 1:1,000 aqueous solution: 0.3-0.5 ml (300-500 mcg). Dose may be given via IM or SC inj.

Child: As 1:1,000 aqueous solution: 0.01 ml/kg (10 mcg/kg). Max: 0.5 ml (500 mcg). Dose may be given via IM or SC inj. Intravenous Advanced cardiac life support

Adult: Initially, 1 mg (10 mL of a 1:10,000 solution), may repeat as often as every 2-3 minutes throughout the resuscitation process. May also be given via intraosseous route at the same dosage. For endotracheal doses: 2-3 times of the IV dose.

Child: Initially, 10 mcg/kg, may repeat as often as every 2-3 minutes throughout the resuscitation process. Endotracheal doses: 100 mcg/kg. Intraosseous doses are the same as IV doses. Max

Dosage: Intraosseous doses for adults and children are the same as IV doses. Intravenous Anaphylactic shock

Adult: 0.5 mg (5 mL of a 1:10,000 solution) given at a slow rate of 100 mcg/minute, stopping when a response is achieved.

Child: 10 mcg/kg. If autoinjectors are used, doses are based on body wt: 15-30 kg: 150 mcg and >30 kg: 300 mcg. Intramuscular Anaphylactic shock

Adult: As 1:1,000 solution: 500 mcg (0.5 ml), repeat every 5 minutes as needed until improvement occurs. For emergency self-admin (e.g. via autoinjector): A dose of 300 mcg (0.3 ml) may be used.

Child: Dose depends on age and weight. Usual dose: 10 mcg/kg. Ophthalmic Ocular hypertension

Adult: Instill 0.5%, 1% or 2% eye drops once or twice daily. Ophthalmic Open-angle glaucoma

Adult: Instill 0.5%, 1% or 2% eye drops once or twice daily.

Intravenous Advanced cardiac life support

Adult: IV (preferably into a central vein): 1 mg (10 mL of a 1:10,000 solution) repeat as often as every 2-3 minutes throughout the resuscitation process. May also be given via other routes. For endotracheal doses: 2-3 times of the IV dose. Intraosseous doses are the same as IV doses.

Child: IV (preferably into a central vein): Initially, 10 mcg/kg. Endotracheal doses: 100 mcg/kg. Intraosseous doses are the same as IV doses. Max

Dosage: Intraosseous doses for adults and children are the same as IV doses. Intravenous Anaphylactic shock

Adult: 0.5 mg (5 mL of a 1:10,000 solution) given at a slow rate of 100 mcg/minute, stopping when a response is achieved.

Child: 10 mcg/kg. If autoinjectors are used, doses are based on body wt: 15-30 kg: 150 mcg and >30 kg: 300 mcg. Intramuscular Acute asthmatic attacks

Adult: 0.3-0.5 mL of a 1:1000 aqueous solution (300-500 mcg). May also be given via SC admin.

Child: 0.01 mL/kg (10 mcg/kg). Max: 0.5 mL(500 mcg). May also be given via SC admin. Intramuscular Anaphylactic shock

Adult: 500 mcg (0.5 ml in 1:1,000 solution), repeat every 5 minutes as needed until improvement occurs.

Child: 10 mcg/kg, using a 1 in 10 000 solution at a rate of ≤1 mL (100 mcg)/ minute. Ophthalmic Open-angle glaucoma and ocular hypertension

Adult: Instill 0.5%, 1% or 2% eye drops once or twice daily. Inhalation Alleviate asthmatic attacks

Adult: Spray: Aqueous solution with an adrenaline content equivalent to 1:100. Pressurised aerosols delivering metered doses equivalent to approximately 160-275 mcg: 1-2 inhalations, may repeat after 3 hr if necessary.

Active ingredients: Epinephrine
Unit description, dosagePrice, USD

List of epipen jr brand and generic drugs

EpiPen Senior (Poland)
Epirenamine
Epirenan
Epirenin (Taiwan)
Epirenin 1 mg/1 mL x 1 mL
Epitrate
Eppy
Eppystabil
Esphygmogenina
Exadrin
Fastject (Luxembourg)
Fastjekt (Germany, Italy, Poland)
Gingi Pak Cord
Cord; Dental; Epinephrine Hydrochloride Racemic 0.5 mg / 2.54 cm
Gingi Pak Cord No 1
Cord; Dental; Epinephrine Hydrochloride 0.5 mg / 2.54 cm
Gingi Pak Dark Braid N 1
Cord; Topical; Epinephrine Hydrochloride Racemic 0.5 mg / 2.54 cm
Gingi Pak Dark Braid N 2
Cord; Topical; Epinephrine Hydrochloride Racemic 0.5 mg / 2.54 cm
Gingi Pak Dark Braid N 3
Cord; Dental; Epinephrine Hydrochloride Racemic 0.5 mg / 2.54 cm
Gingi Pak Dark Braid N O
Cord; Dental; Epinephrine Racemic 0.5 mg / 2.54 cm
Gingi-Pak
Gingiyarn with Epinephrine No 1
Cord; Dental; Epinephrine Hydrochloride Racemic 0.55 mg / 2.5 cm
Gingiyarn with Epinephrine No 2
Cord; Dental; Epinephrine Hydrochloride Racemic 1.05 mg / 2.5 cm
Gingiyarn with Epinephrine No 3
Cord; Dental; Epinephrine Hydrochloride Racemic 1.95 mg / 2.5 cm
Glaucon (United States)
Glaufrin
Glauposine
Glycirenan
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Homeopathic Medicine S No. 211
Drops; Oral; Epinephrine 30 c / ml
Hypernephrin
Hyporenin
InfectoKrupp
InfectoKrupp Inhal (Germany)
Injectio Adrenalini (Poland)
Intranefrin
IOP
Jext (Ireland, Norway, Spain, Sweden, Switzerland, United Kingdom)

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