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Flungofil

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Flungofil uses and description

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Flungofil - Flungofil is an antifungal antibiotic.

Flungofil is used to treat infections caused by fungus, which can invade any part of the body including the mouth, throat, esophagus, lungs, bladder, genital area, and the blood.

Flungofil is also used to prevent fungal infection in people with weak immune systems caused by cancer treatment, bone marrow transplant, or diseases such as AIDS.

Flungofil may also be used for purposes not listed in this medication guide.

Pharmacology: Interferes with the formation of fungal cell membrane, causing leakage of cellular contents and cell death.

Indication: Oropharyngeal and esophageal candidiasis; vaginal candidiasis; prevention of candidiasis in bone marrow transplant; cryptococcal meningitis.

Flungofil is an antifungal drug from the group of triazole derivatives. Inhibits the synthesis of ergosterol disrupting the permeability of the cell wall. This medication is active against Candida, Microsporum, Cryptococcus neoformans, Trichophyton.

Flungofil, a synthetic antifungal agent of the imidazole class, is used to treat vaginal candidiasis. It inhibits the fungal lanosterol 14 alpha-demethylase which thereby prevents the formation of ergosterol which is an essential component in the fungal cell membrane.

Indications:

  • Skin infections caused by fungi such as athlete\'s foot (tinea pedis), ringworm (tinea corporis), jock itch (tinea cruris), pityriasis versicolor,
  • Skin infections caused by candida albicans
  • Candida infection that affects mouth mucous lining (oral thrush), urinary tract, throat, lungs, bloodstream, heart.
  • Vaginal thrush(vaginits) caused by Candida albicans
  • Inflammation of the male genitals and/or foreskin (candidal balanitis).
  • Fungal infections caused by Cryptococcus fungi (cryptococcosis), including cryptococcal meningitis and infections affecting the lungs or skin.
  • Preventing fungal infections caused by fungi in patients with a weakened immunity and low white blood cell counts due to chemotherapy, radiotherapy or bone marrow transplants.
  • Prophylaxis of a disease caused by Cryptococcus fungi, eg cryptococcal meningitis, in patients with AIDS.

  • Flungofil is an antifungal medicine. It is used to prevent or treat fungal infections of the vagina, mouth, throat, digestive tract, lungs, brain, urinary tract, blood and other organs.

    Oral Superficial mucosal candidiasis

    Adult: (Except genital candidiasis) Usual dose: 50 mg daily, may increase to 100 mg daily if needed. Recommended treatment duration: 7-14 days (oropharyngeal candidiasis, except in severely immunocompromised patients), 14 days (atrophic oral candidiasis associated with dentures), 14-30 days (other mucosal candidiasis including oesophagitis).

    Child: >4 wk: Loading dose: 6 mg/kg followed by 3 mg/kg daily. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Vaginal candidiasis

    Adult: 150 mg as a single dose. Oral Candidal balanitis

    Adult: 150 mg as a single dose. Oral Dermatophytosis

    Adult: 50 mg daily for up to 6 wk. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Pityriasis versicolor

    Adult: 50 mg daily for up to 6 wk. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Cutaneous candidiasis

    Adult: 50 mg daily for up to 6 wk. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Systemic candidiasis

    Adult: Initially, 400 mg followed by 200-400 mg daily. Max: 800 mg daily in severe infections. Treatment duration is based on clinical and mycological response but is usually at least 6-8 wk in cryptococcal meningitis. May also be given via IV infusion. To prevent relapse after a primary course of treatment for acute cryptococcal meningitis in AIDS patients: 100-200 mg daily, may also be given via IV admin.

    Child: >4 wk: 6-12 mg/kg daily; same doses may given every 72 hr in neonates up to 2 wk and every 48 hr in neonates 2-4 wk. Max: 400 mg daily. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Cryptococcal infections

    Adult: Initially, 400 mg followed by 200-400 mg daily. Max: 800 mg daily in severe infections. Treatment duration is based on clinical and mycological response but is usually at least 6-8 wk in cryptococcal meningitis. May also be given via IV infusion. To prevent relapse after a primary course of treatment for acute cryptococcal meningitis in AIDS patients: 100-200 mg daily, may also be given via IV admin.

    Child: >4 wk: 6-12 mg/kg daily; same doses may given every 72 hr in neonates up to 2 wk and every 48 hr in neonates 2-4 wk. Max: 400 mg daily. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Prophylaxis of fungal infections in immunocompromised patients

    Adult: 50-400 mg daily. May also be given via IV infusion.

    Child: 3-12 mg/kg daily; may also be given via IV infusion. For infants <2 wk, doses should be given every 72 hr; 2-4 wk, doses should be given every 48 hr. Max: 400 mg daily, or 12 mg/kg at recommended intervals in infants. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses.

    Oral Superficial mucosal candidiasis

    Adult: (Except genital candidiasis) Usual dose: 50 mg daily, may increase to 100 mg daily if needed. Recommended treatment duration: 7-14 days (oropharyngeal candidiasis, except in severely immunocompromised patients), 14 days (atrophic oral candidiasis associated with dentures), 14-30 days (other mucosal candidiasis including oesophagitis).

    Child: >4 wk: Loading dose: 6 mg/kg followed by 3 mg/kg daily. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Vaginal candidiasis

    Adult: 150 mg as a single dose. Oral Candidal balanitis

    Adult: 150 mg as a single dose. Oral Dermatophytosis

    Adult: 50 mg daily for up to 6 wk. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Pityriasis versicolor

    Adult: 50 mg daily for up to 6 wk. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Cutaneous candidiasis

    Adult: 50 mg daily for up to 6 wk. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Systemic candidiasis

    Adult: Initially, 400 mg followed by 200-400 mg daily. Max: 800 mg daily in severe infections. Treatment duration is based on clinical and mycological response but is usually at least 6-8 wk in cryptococcal meningitis. May also be given via IV infusion. To prevent relapse after a primary course of treatment for acute cryptococcal meningitis in AIDS patients: 100-200 mg daily, may also be given via IV admin.

    Child: >4 wk: 6-12 mg/kg daily; same doses may given every 72 hr in neonates up to 2 wk and every 48 hr in neonates 2-4 wk. Max: 400 mg daily. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Cryptococcal infections

    Adult: Initially, 400 mg followed by 200-400 mg daily. Max: 800 mg daily in severe infections. Treatment duration is based on clinical and mycological response but is usually at least 6-8 wk in cryptococcal meningitis. May also be given via IV infusion. To prevent relapse after a primary course of treatment for acute cryptococcal meningitis in AIDS patients: 100-200 mg daily, may also be given via IV admin.

    Child: >4 wk: 6-12 mg/kg daily; same doses may given every 72 hr in neonates up to 2 wk and every 48 hr in neonates 2-4 wk. Max: 400 mg daily. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Prophylaxis of fungal infections in immunocompromised patients

    Adult: 50-400 mg daily. May also be given via IV infusion.

    Child: 3-12 mg/kg daily; may also be given via IV infusion. For infants <2 wk, doses should be given every 72 hr; 2-4 wk, doses should be given every 48 hr. Max: 400 mg daily, or 12 mg/kg at recommended intervals in infants. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Special Populations: Renal impairment: Initially, administer normal loading or initial doses followed by maintenance doses based on creatinine clearance. CrCl: >50 mL/min: ½ of the standard dose. Patients on regular haemodialysis should be given a standard dose of Flungofil every dialysis session.

    Oral Superficial mucosal candidiasis

    Adult: 50 mg daily increased to 100 mg daily. Recommended treatment duration: 7-14 days (oropharyngeal candidiasis), 14 days (atrophic oral candidiasis associated with dentures), 14-30 days (other mucosal candidal infections including oesophagitis).

    Child: >4 wk: Loading dose: 6 mg/kg followed by 3 mg/kg daily. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Vaginal candidiasis

    Adult: 150 mg as a single dose. Oral Candidal balanitis

    Adult: 150 mg as a single dose. Oral Dermatophytosis, pityriasis versicolor and candida infections

    Adult: 50 mg daily for up to 6 wk. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Systemic candidasis

    Adult: Initially, 400 mg followed by 200-400 mg daily. Max: 800 mg daily in severe infections. Usual treatment duration: At least 6-8 wk in cryptococcal meningitis. May also be given via IV infusion.

    Child: >4 wk: 6-12 mg/kg daily; same doses may given every 72 hr in neonates up to 2 wk and every 48 hr in neonates 2-4 wk. Max: 400 mg daily. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Cryptococcal infections including meningitis

    Adult: Initially, 400 mg followed by 200-400 mg daily. Max: 800 mg daily in severe infections. Usual treatment duration: At least 6-8 wk in cryptococcal meningitis. May also be given via IV infusion.

    Child: >4 wk: 6-12 mg/kg daily; same doses may given every 72 hr in neonates up to 2 wk and every 48 hr in neonates 2-4 wk. Max: 400 mg daily. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Prevention of relapse following a primary course of antifungal treatment for acute cryptococcal infections in patients with AIDS

    Adult: 100-200 mg daily. May also be given intravenously. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses. Oral Prophylaxis of fungal infections in immunocompromised patients

    Adult: 50-400 mg daily. May also be given via IV infusion.

    Child: 3-12 mg/kg daily; may also be given via IV infusion. For infants <2 wk, doses should be given every 72 hr; 2-4 wk, doses should be given every 48 hr. Max: 400 mg daily, or 12 mg/kg at recommended intervals in infants. Renal impairment: Normal initial doses; adjust subsequent doses based on CrCl. Patients on dialysis: Single recommended dose after each session. CrCl (ml/min) Dosage Recommendation <50 and not receiving dialysis Maintenance dose: 50% of the recommended doses.

    Indications:

    Adult: PO Superficial mucosal candidiasis 50 mg/day, up to 100 mg/day. Treatment duration: 7-30 days depending on condition. Candidal balanitis ; Vag candidiasis 150 mg as a single dose. Dermatophytosis; Pityriasis versicolor ; Cutaneous candidiasis 50 mg/day, for up to 6 wk. Systemic candidiasis; Cryptococcal infections Initial: 400 mg, then 200-400 mg/day. Max: 800 mg/day in severe cases. Prevention of relapse after a primary course of antifungal treatment for acute cryptococcal infections in AIDS patients 100-200 mg/day. Prophylaxis of fungal infections in immunocompromised patients 50-400 mg/day.

    Indications: Superficial mucosal candidiasis.

    Candidal balanitis, vaginal candidiasis.

    Dermatophytosis, pityriasis, versicolor and candida infections.

    Cryptococcal infections including meningitis, systemic candidasis.

    Prevention of relapse following a primary course of antifungal treatment for acute cryptococcal infections in patients with aids.

    Prophylaxis of fungal infections in immunocompromised patients.

    Active ingredients: Fluconazole
    Unit description, dosagePrice, USD

    List of flungofil brand and generic drugs

    Flungi
    Flungi 150 mg Tablet$ 0.46
    FLUNID (India)
    150 mg x 1's$ 0.28
    Flunid 150 mg Tablet$ 0.28
    Flunid 150mg TAB / 1$ 0.28
    FLUNIF (India)
    150 mg x 10's$ 5.37
    Flunif 5 mg Tablet$ 0.03
    Flunif 10 mg Tablet$ 0.05
    Flunif 150 mg Tablet$ 0.54
    Flunif 150mg TAB / 10$ 5.37
    Flunizol (Switzerland)
    Capsule; Oral; Fluconazole 150 mg
    Capsule; Oral; Fluconazole 200 mg
    Capsule; Oral; Fluconazole 50 mg
    Capsules; Oral; Fluconazole 150 mg
    Capsules; Oral; Fluconazole 200 mg
    Capsules; Oral; Fluconazole 50 mg
    FLUNOVA (India)
    FLUNOVA Capsule/ Tablet / 150mg (1 units)$ 0.17
    FLUNOVA Dispersible Tablet / 50mg (1 units)$ 0.41
    FLUNOVA Capsule/ Tablet / 200mg (4 units)$ 0.83
    Flunova 50mg DT-TAB / 4$ 0.48
    Flunova 100mg TAB / 1$ 0.20
    Flunova 200mg TAB / 4$ 0.98
    150 mg x 1's$ 0.20
    200 mg x 4's$ 0.98
    50 mg x 4's$ 0.48
    Flunova Eye Drop$ 0.49
    Flunova 200 mg Tablet$ 0.25
    Flunova 150 mg Tablet$ 0.20
    FLUNOVA DPS (India)
    0.3 % x 5ml$ 0.49
    Flunova Dps 0.3% EYE DPS / 5ml$ 0.49
    Flunova DT
    Flunova DT 50 mg Tablet$ 0.12
    Flunus
    Flunus 150mg CAP / 10$ 5.19
    Fluoc
    Fluoc 150 mg Tablet$ 0.22
    Fluocod
    Fluocod 150 mg Tablet$ 0.03
    FLUOL (India)
    FLUOL Capsule/ Tablet / 150mg (1 units)$ 0.37
    Fluol 150mg TAB / 10$ 4.26
    150 mg x 20's$ 4.26
    Fluol 150 mg Tablet$ 0.21
    Fluol Skin 15 gm Cream$ 0.70
    Fluotec
    Flupax
    Flupax 150 mg Capsule$ 0.44
    Fluplas
    Fluplas 150 mg Tablet$ 0.28
    Flurabin (Japan)

    Show all Flungofil generic names
     
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