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Fulsed Injection

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Fulsed Injection uses and description

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Fulsed Injection - Fulsed Injection is a short-acting benzodiazepine central nervous system (CNS) depressant. Pharmacodynamic properties of Fulsed Injection and its metabolites, which are similar to those of other benzodiazepines, include sedative, anxiolytic, amnesic and hypnotic activities. Benzodiazepine pharmacologic effects appear to result from reversible interactions with the (gamma)-amino butyric acid (GABA) benzodiazepine receptor in the CNS, the major inhibitory neurotransmitter in the central nervous system. The action of Fulsed Injection is readily reversed by the benzodiazepine receptor antagonist, flumazenil.

Fulsed Injection is a sleeping pill. It helps you to sleep if you have problems sleeping (also known as insomnia). Fulsed Injection may also be used to help you relax during surgical and dental procedures. It may also be used for other medical conditions as decided by your doctor, such as anxiety.

Oral Short-term management of insomnia

Adult: 7.5-15 mg given at night. Oral Sedation for dental and minor surgical procedures

Child: ≥6 mth: Single dose of 250-500 mcg/kg, up to a max of 20 mg. Younger patients (6 mth-<6 yr) may require up to 1 mg/kg. Oral Premedication in surgery

Child: ≥6 mth: Single dose of 250-500 mcg/kg, up to a max of 20 mg. Younger patients (6 mth-<6 yr) may require up to 1 mg/kg. Intramuscular Premedication in surgery

Adult: 70-100 mcg/kg (usual dose: 5 mg) given 20-60 minutes before surgery by deep IM inj.

Child: ≥1 yr: 80-200 mcg/kg given 20-60 minutes before surgery by deep IM inj.

Elderly: 20-50 mcg/kg given 20-60 minutes before surgery by deep IM inj. Parenteral Sedation for dental and minor surgical procedures

Adult: IV admin: Initially, up to 2.5 mg given over at least 2-5 minutes, 5-10 minutes before procedure. Repeat after at least 2 minutes if necessary. Usual total: 3.5-5 mg. Max total: 7.5 mg.

Child: IV admin: 6 mth-5 yr: Initial: 50-100 mcg/kg given over 2 minutes, increase slowly at 2-minute intervals up to a total of 600 mcg/kg, max total dose: 6 mg. 6-12 yr: 25-50 mcg/kg given over 2 minutes and increase slowly at 2-minute intervals up to a total of 400 mcg/kg; max total dose: 10 mg. IM admin (used only in exceptional cases): 1-15 yr: 50-150 mcg/kg; max: 10 mg.

Elderly: Initially 1-1.5 mg given over 2 min, increased by increments of 0.5-1 mg at 2 min intervals as needed. Intravenous Induction of anaesthesia

Adult: 150-200 mcg/kg by slow inj in premedicated patients and at least 300 mcg/kg for those who have not received a premedicant. Additional doses may be required to complete induction, up to 600 mcg/kg in resistant cases.

Child: >7 yr: 150 mcg/kg. Max total: 500 mcg/kg (not >25 mg).

Elderly: 100-200 mcg/kg in divided doses at 2-minute intervals. Intravenous Sedation in critical care

Adult: Loading dose: 30-300 mcg/kg given as infusion over 5 minutes to induce sedation. Maintenance dose: 20-200 mcg/kg/hr. For patients with hypothermia, hypovolaemia or vasoconstriction: Reduce or omit loading dose, and reduce maintenance dose.

Child: Neonates with gestational age <32 wk: 30 mcg/kg/hr by continuous IV infusion. Neonates with gestational age >32 wk and who are <6 mth: 60 mcg/kg/hr. ≥6 mth: Initial loading dose of 50-200 mcg/kg given by slow IV inj; maintenance dose of 60-120 mcg/kg/hr given as IV infusion. In obese paediatric patients, calculate dose based on ideal wt.

Elderly: Dosage may need to be reduced. Rectal Sedation for dental and minor surgical procedures

Child: >6 mth: 300-500 mcg/kg as a single dose. May dilute with water for inj up to a total volume of 10 mL if the volume is too small. Rectal Premedication in surgery

Child: >6 mth: 300-500 mcg/kg as a single dose. May dilute with water for inj up to a total volume of 10 mL if the volume is too small. Special Populations: Dosage in intensive care may need to be reduced in patients with hypovolaemia, vasoconstriction or hypothermia. Reconstitution: Fulsed Injection solution for injection may be administered rectally. The inj solution may be diluted with Water for Injections up to a total volume of 10 ml if the volume is too small.

Oral Short-term management of insomnia

Adult: 7.5-15 mg given at night. Oral Sedation for dental and minor surgical procedures

Child: ≥6 mth: Single dose of 250-500 mcg/kg, up to a max of 20 mg. Younger patients (6 mth-<6 yr) may require up to 1 mg/kg. Oral Premedication in surgery

Child: ≥6 mth: Single dose of 250-500 mcg/kg, up to a max of 20 mg. Younger patients (6 mth-<6 yr) may require up to 1 mg/kg. Intramuscular Premedication in surgery

Adult: 70-100 mcg/kg (usual dose: 5 mg) given 20-60 minutes before surgery by deep IM inj.

Child: ≥1 yr: 80-200 mcg/kg given 20-60 minutes before surgery by deep IM inj.

Elderly: 20-50 mcg/kg given 20-60 minutes before surgery by deep IM inj. Parenteral Sedation for dental and minor surgical procedures

Adult: IV admin: Initially, up to 2.5 mg given over at least 2-5 minutes, 5-10 minutes before procedure. Repeat after at least 2 minutes if necessary. Usual total: 3.5-5 mg. Max total: 7.5 mg.

Child: IV admin: 6 mth-5 yr: Initial: 50-100 mcg/kg given over 2 minutes, increase slowly at 2-minute intervals up to a total of 600 mcg/kg, max total dose: 6 mg. 6-12 yr: 25-50 mcg/kg given over 2 minutes and increase slowly at 2-minute intervals up to a total of 400 mcg/kg; max total dose: 10 mg. IM admin (used only in exceptional cases): 1-15 yr: 50-150 mcg/kg; max: 10 mg.

Elderly: Initially 1-1.5 mg given over 2 min, increased by increments of 0.5-1 mg at 2 min intervals as needed. Intravenous Induction of anaesthesia

Adult: 150-200 mcg/kg by slow inj in premedicated patients and at least 300 mcg/kg for those who have not received a premedicant. Additional doses may be required to complete induction, up to 600 mcg/kg in resistant cases.

Child: >7 yr: 150 mcg/kg. Max total: 500 mcg/kg (not >25 mg).

Elderly: 100-200 mcg/kg in divided doses at 2-minute intervals. Intravenous Sedation in critical care

Adult: Loading dose: 30-300 mcg/kg given as infusion over 5 minutes to induce sedation. Maintenance dose: 20-200 mcg/kg/hr. For patients with hypothermia, hypovolaemia or vasoconstriction: Reduce or omit loading dose, and reduce maintenance dose.

Child: Neonates with gestational age <32 wk: 30 mcg/kg/hr by continuous IV infusion. Neonates with gestational age >32 wk and who are <6 mth: 60 mcg/kg/hr. ≥6 mth: Initial loading dose of 50-200 mcg/kg given by slow IV inj; maintenance dose of 60-120 mcg/kg/hr given as IV infusion. In obese paediatric patients, calculate dose based on ideal wt.

Elderly: Dosage may need to be reduced. Rectal Sedation for dental and minor surgical procedures

Child: >6 mth: 300-500 mcg/kg as a single dose. May dilute with water for inj up to a total volume of 10 mL if the volume is too small. Rectal Premedication in surgery

Child: >6 mth: 300-500 mcg/kg as a single dose. May dilute with water for inj up to a total volume of 10 mL if the volume is too small. Special Populations: If premedicated with opioids, debilitation and neonates, the dose should be adjusted appropriately. Reconstitution: Fulsed Injection solution for injection may be administered rectally. The inj solution may be diluted with Water for Injections up to a total volume of 10 ml if the volume is too small.

Oral Short-term management of insomnia

Adult: 7.5-15 mg given at night. Oral Sedation for dental and minor surgical procedures

Child: ≥6 mth: Single dose of 250-500 mcg/kg, up to a max of 20 mg. Younger patients (6 mth-<6 yr) may require up to 1 mg/kg. Oral Premedication in surgical procedures

Child: ≥6 mth: Single dose of 250-500 mcg/kg, up to a max of 20 mg. Younger patients (6 mth-<6 yr) may require up to 1 mg/kg. Intravenous For induction of anaesthesia

Adult: 150-200 mcg/kg by slow inj in premedicated patients and at least 300 mcg/kg for those who have not received a premedicant. Additional doses may be required to complete induction, up to 600 mcg/kg in resistant cases.

Child: >7 yr: 150 mcg/kg. Max total: 500 mcg/kg (not >25 mg).

Elderly: 100-200 mcg/kg in divided doses at 2-minute intervals. Intravenous Sedation of patients in intensive care

Adult: Loading dose: 30-300 mcg/kg given as infusion over 5 minutes to induce sedation. Maintenance dose: 20-200 mcg/kg/hr. For patients with hypothermia, hypovolaemia or vasoconstriction: Reduce or omit loading dose, and reduce maintenance dose.

Child: Neonates with gestational age <32 wk: 30 mcg/kg/hr by continuous IV infusion. Neonates with gestational age >32 wk and who are <6 mth: 60 mcg/kg/hr. ≥6 mth: Initial loading dose of 50-200 mcg/kg given by slow IV inj; maintenance dose of 60-120 mcg/kg/hr given as IV infusion. In obese paediatric patients, calculate dose based on ideal wt.

Elderly: Dosage may need to be reduced. Intramuscular Premedication in surgical procedures

Adult: 70-100 mcg/kg (usual dose: 5 mg) given 20-60 minutes before surgery by deep IM inj.

Child: ≥1 yr: 80-200 mcg/kg given 20-60 minutes before surgery by deep IM inj.

Elderly: 20-50 mcg/kg given 20-60 minutes before surgery by deep IM inj. Parenteral Sedation for dental and minor surgical procedures

Adult: IV admin: Initially, up to 2.5 mg given over at least 2-5 minutes, 5-10 minutes before procedure. Repeat after at least 2 minutes if necessary. Usual total: 3.5-5 mg. Max total: 7.5 mg.

Child: IV admin: 6 mth-5 yr: Initial: 50-100 mcg/kg given over 2 minutes, increase slowly at 2-minute intervals up to a total of 600 mcg/kg, max total dose: 6 mg. 6-12 yr: 25-50 mcg/kg given over 2 minutes and increase slowly at 2-minute intervals up to a total of 400 mcg/kg; max total dose: 10 mg. IM admin (used only in exceptional cases): 1-15 yr: 50-150 mcg/kg; max: 10 mg.

Elderly: Initially 1-1.5 mg given over 2 min, increased by increments of 0.5-1 mg at 2 min intervals as needed. Rectal Sedation for dental and minor surgical procedures

Child: >6 mth: 300-500 mcg/kg as a single dose. May dilute with water for inj up to a total volume of 10 mL if the volume is too small. Rectal Premedication in surgical procedures

Child: >6 mth: 300-500 mcg/kg as a single dose. May dilute with water for inj up to a total volume of 10 mL if the volume is too small. Special Populations: Dosage in intensive care may need to be reduced in patients with hypovolaemia, vasoconstriction or hypothermia. Reconstitution: Fulsed Injection solution for injection may be administered rectally. The inj solution may be diluted with Water for Injections up to a total volume of 10 ml if the volume is too small.

orally : short term treatment of insomnia. intramuscularly or intravenously for preoperative sedation/anxiolysis/amnesia;• intravenously as an agent for sedation/anxiolysis/amnesia prior to or during diagnostic, therapeutic or endoscopic procedures, such as bronchoscopy, gastroscopy, cystoscopy, coronary angiography, cardiac catheterization, oncology procedures, radiologic procedures, suture of lacerations and other procedures either alone or in combination with other CNS depressants;• intravenously for induction of general anesthesia, before administration of other anesthetic agents. With the use of narcotic premedication, induction of anesthesia can be attained within a relatively narrow dose range and in a short period of time. Intravenous Fulsed Injection can also be used as a component of intravenous supplementation of nitrous oxide and oxygen (balanced anesthesia);• continuous intravenous infusion for sedation of intubated and mechanically ventilated patients as a component of anesthesia or during treatment in a critical care setting. Fulsed Injection is associated with a high incidence of partial or complete impairment of recall for the next several hours.

Indications:

Adult: PO Insomnia 7.5-15 mg/day at bedtime. IV Sedation for dental and minor surgical procedures Initial: Up to 2.5 mg given 5-10 mins before procedure. Repeat after at least 2 mins if needed. Usual total: 3.5-5 mg. Max total: 7.5 mg. Induction of anesth 150-200 mcg/kg in premedicated patients and at least 300 mcg/kg for those who have not received premed. Resistant cases: Up to 600 mcg/kg. Sedation in critical care Initial: 30-300 mcg/kg.

Maintenance: 20-200 mcg/kg/hr. IM Premed in surgical procedures 70-80 mcg/kg 20-60 mins pre-op by deep inj.

Active ingredients: Midazolam
Unit description, dosagePrice, USD

List of fulsed injection brand and generic drugs

Garen (Bangladesh)
Gobbizolam (Argentina)
Hikma Midazolam (Bahrain, Oman, Tunisia)
Hipnazolam (Brazil)
Hipnoz (Indonesia)
Hipnoz 5 mg/5 mL x 5's$ 7.65
Hipnoz 15 mg/3 mL x 5's$ 18.36
Hypnocum (Bangladesh)
Hypnofast (Bangladesh)
Hypnovel (Australia, Bahrain, Egypt, France, Iran, Iraq, Jordan, Kuwait, Lebanon, New Zealand, Oman, Qatar, Saudi Arabia, Syria, United Arab Emirates, United Kingdom, Yemen)
Injectable; Injection; Midazolam Hydrochloride 1 mg / ml
Injectable; Injection; Midazolam Hydrochloride 2 mg / ml
Injectable; Injection; Midazolam Hydrochloride 5 mg / ml
Hypnovel 5 mg/1 mL x 10 oáng x 5 mL
Hypnovel 5 mg/5 mL x 6 oáng
Hypnovel 50 mg/10 mL x 6 oáng
Hypnovet (United Kingdom)
Hypozam (Philippines)
Hypozam (amp) 1 mg/1 mL x 3 mL x 10's
Hypozam 1 mg/1 mL x 5 mL x 10's
INSED (India)
0.5 mg x 1 dose x 50mdi$ 4.44
Insed 0.5mg x 1dose N-SPY / 50mdi$ 4.44
International Apex Midazolam (Philippines)
Ipnodis Medis (Tunisia)
Ipnovel
Li Yue Xi (China)
MEZOLAM (India)
MEZOLAM Injection / 5mg per ml (10 x 1ml units)$ 6.00
MEZOLAM Injection / 1mg per ml (5ml units)$ 0.67
MEZOLAM Injection / 1mg per ml (10ml units)$ 1.17
Mezolam 7.5mg TAB / 2
Mezolam 1mg/mL VIAL / 10ml$ 1.27
Mezolam 1mg/mL VIAL / 5ml$ 0.77
Mezolam 5mg/mL VIAL / 10ml$ 6.50
1 mg x 1 mL x 10ml$ 1.27
1 mg x 1 mL x 5ml$ 0.77
5 mg x 1 mL x 10ml$ 6.50
7.5 mg x 2's
2 mg x 1 mL x 15ml$ 1.67
Mezolam 2mg x 1mL SYR / 15ml$ 1.67
Mezolam - -
Miben (India)
Miben 10mg VIAL / 1$ 1.40
Miben 1mg VIAL / 1$ 0.83
Miben 5mg AMP / 5$ 3.50
5 mg x 5's$ 3.50

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