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Globentyl

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Globentyl uses and description

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Globentyl - NSAIDs. It has anti-inflammatory, analgesic and antipyretic effect, and inhibits platelet aggregation. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid which is a precursor of prostaglandins which play a major role in the pathogenesis of inflammation, pain and fever. Reduction of prostaglandins (mainly E1) in the thermoregulation center leads to a decrease in body temperature due to expansion of blood vessels of the skin and increase perspiration. Analgesic effect is due to both central and peripheral effects. Reduces aggregation, platelet adhesion and thrombus formation through suppression of synthesis of thromboxane A2 in platelets.

Reduces mortality and risk of myocardial infarction in unstable stenocardia. It is effective in primary prevention of cardio-vascular system and secondary prevention of myocardial infarction. At a daily dose of 6 g or more inhibits the synthesis of prothrombin in the liver and increases the prothrombin time. Increases fibrinolytic activity of plasma and reduces the concentration of vitamin K-dependent coagulation factors (II, VII, IX, X). Increases the rate of hemorrhagic complications in carrying out surgical procedures, increases the risk of bleeding during therapy with anticoagulants. It stimulates the excretion of uric acid (violating its reabsorption in the renal tubules) but in high doses. The blockade of COX-1 in the mucosa of the stomach leads to inhibition of gastroprotective prostaglandins, which may lead to ulceration of the mucous membrane and subsequent bleeding.

Globentyl (acetylsalicylic acid) is an analgesic, antipyretic, antirheumatic, and anti-inflammatory agent. Globentyl\'s mode of action as an antiinflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. Globentyl appears to produce analgesia by virtue of both a peripheral and CNS effect. Peripherally, Globentyl acts by inhibiting the synthesis and release of prostaglandins. Acting centrally, it would appear to produce analgesia at a hypothalamic site in the brain, although the mode of action is not known. Globentyl also acts on the hypothalamus to produce antipyresis; heat dissipation is increased as a result of vasodilation and increased peripheral blood flow. Globentyl\'s antipyretic activity may also be related to inhibition of synthesis and release of prostaglandins.

Indication: For use in the temporary relief of various forms of pain, inflammation associated with various conditions (including rheumatoid arthritis, juvenile rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, and ankylosing spondylitis), and is also used to reduce the risk of death and/or nonfatal myocardial infarction in patients with a previous infarction or unstable angina pectoris.

Indications: fever, pain, rheumatic disorders

Globentyl is a NSAIDs. It has anti-inflammatory, analgesic and antipyretic effect, and inhibits platelet aggregation. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid which is a precursor of prostaglandins which play a major role in the pathogenesis of inflammation, pain and fever. Reduction of prostaglandins (mainly E1) in the thermoregulation center leads to a decrease in body temperature due to expansion of blood vessels of the skin and increase perspiration. Analgesic effect of Globentyl is due to both central and peripheral effects. Reduces aggregation, platelet adhesion and thrombus formation through suppression of synthesis of thromboxane A2 in platelets.

Active ingredients: Aspirin
Unit description, dosagePrice, USD

List of globentyl brand and generic drugs

Genuine Bayer Aspirin
Tablets; Oral; Aspirin 325 mg
Globoid (Norway)
Glyprin (Singapore)
Glyprin 30's
Glyprin 60's
Glyprin 90's
Glyprin 100's
Glyprin 120's
Glyprin 3 x 10's
Godamed ASS TAH (Germany)
Godasal
Golden-Udder (United Kingdom)
Good Neighbor Pharmacy Aspirin (United States)
Good Sense Aspirin (United States)
Goody's Body Pain Powders
Powder; Oral; Aspirin
Goody's Extra Strength Headache Powders
Powder; Oral; Aspirin
GR ASA
GR ASA 50 mg Tablet$ 0.02
GRA (India)
GRA 81mg TAB / 14$ 0.36
GRA 82mg TAB / 14$ 0.38
GRA 162.5mg TAB / 14$ 0.47
GRA 165mg TAB / 14
81 mg x 14's$ 0.36
82 mg x 14's$ 0.38
162.5 mg x 14's$ 0.47
165 mg x 14's
Gra 82 mg Tablet$ 0.03
GRA 162.5 mg Tablet$ 0.03
GRA 81 mg Tablet$ 0.03
Grippesin (Argentina)
Haemogrel-A (India)
Haemogrel-A Clopidogrel 75 mg, Aspirin 150mg. TAB / 10$ 0.63
10's$ 0.63
Halfprin (United States)
Hassapirin (Chile)
Hassapirin Forte (Chile)
Hassapirin Puro
Hassapirin-Puro (Chile)
Headache Tablets
Tablet; Oral; Aspirin
Tablet; Oral; Aspirin 300 mg
Tablets; Oral; Aspirin
Tablets; Oral; Aspirin 300 mg
Health Mart Aspirin (United States)
Heartline
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