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KadeFungin 3

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KadeFungin 3 uses and description

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KadeFungin 3 - Pharmacology: Inhibits yeast growth by increasing cell membrane permeability in susceptible fungi.

Indication: Topical use

Treatment of tinea pedis (athlete\'s foot), tinea cruris (jock itch), tinea corporis (ringworm), candidiasis, and tinea versicolor.

Oral use (troche)

Treatment of oropharyngeal candidiasis; prophylaxis of oropharyngeal candidiasis in specific groups of immunocompromised patients.

Vaginal use

Treatment of vulvovaginal candidiasis.

KadeFungin 3 is an antifungal agent of imidazole derivatives group for topical use. This medication has an effect at the expense of the synthesis of ergosterol, which is part of the cell membrane of fungi. KadeFungin 3 has a broad spectrum of action.

KadeFungin 3 is active against dermatophytes, molds, fungi of the genus Candida, Malassezia furfur.

This drug is also active against Corynebacterium minutissimum, Streptococcus spp., Staphylococcus spp., Trichomonas vaginalis.

KadeFungin 3, an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol, an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. Betamethasone and KadeFungin 3 are used together to treat cutaneous tinea infections. In studies in fungal cultures, the minimum fungicidal concentration of KadeFungin 3 caused leakage of intracellular phosphorous compounds into the ambient medium with concomitant breakdown of cellular nucleic acids, and accelerated potassium etflux. Both of these events began rapidly and extensively after addition of the drug to the cultures. The primary action of KadeFungin 3 is against dividing and growing organisms.

Clotrimazole is is an antimycotic medicine used to treat infections with yeasts and fungi. It works by interfering with yeasts and fungi cell membranes. Clotrimazole stops the fungi from producing a substance called ergosterol. Ergosterol is an essential component of fungal cell membranes. The decreased production of ergosterol causes holes to appear in cell membrane of fungi and this kills them.

Indications:

  • Fungal infection of the groin (tinea cruris).
  • Ringworm (tinea corporis).
  • Athlete\'s foot (tinea pedis).
  • Sweat rash caused by infection with Candida albicans
  • Penis inflammation (candidal balanitis) caused by Candida albicans (this conditionis also known as thrush).
  • the external symptoms (candidal vulvitis) of vaginal thrush (candidal vaginitis)
  • Fungal nappy rash which is caused by Candida albicans.

  • Oral Oropharyngeal candidiasis

    Adult: Per lozenge contains 10 mg clotrimazole: Suck 1 lozenge 5 times daily for 14 days. For prevention in patients receiving immunosuppressant therapy: 1 lozenge tid for the immunosuppressant treatment duration. Otic/Aural Fungal otitis externa

    Adult: Apply 1% solution to affected area. Topical/Cutaneous Skin fungal infections

    Adult: Apply a 1% cream/lotion/solution bid-tid for 2-4 wk, may be used with a 1% powder to prevent reinfection. Vaginal Vulvovaginal candidiasis

    Adult: As pessary: 100 mg daily for 6 days, 200 mg daily for 3 days or 500 mg as a single dose; alternatively, apply 1, 2 or 10% cream.

    Oral Oropharyngeal candidiasis

    Adult: Per lozenge contains 10 mg clotrimazole: Suck 1 lozenge 5 times daily for 14 days. For prevention in patients receiving immunosuppressant therapy: 1 lozenge tid for the immunosuppressant treatment duration. Vaginal Vulvovaginal candidiasis

    Adult: As pessary: 100 mg daily for 6 days, 200 mg daily for 3 days or 500 mg as a single dose; alternatively, apply 1, 2 or 10% cream. Otic/Aural Fungal otitis externa

    Adult: Apply 1% solution to affected area. Topical/Cutaneous Fungal skin infections

    Adult: Apply a 1% cream/lotion/solution bid-tid for 2-4 wk, may be used with a 1% powder to prevent reinfection.

    Indications: LIsted in Dosage.

    For the treatment of skin infections due to dermatophytes (e.g. trycophyton species), yeasts (e.g. candida species), moulds and other fungi. These include ringworm (tinea) infections, athlete’s foot, paronychia, pityriasis versicolor, erythrasma and intertrigo, as well as fungal nappy rash, candidal vulvitis and candidal balanitis.

    Indications: Vulvo-vaginal candidiasis, trichomonas vaginitis, non specific vaginitis, mixed vaginal infections.

    Infective leucorrhoeas.

    Gram positive and gram negative bacteria.

    Fungal infections of skin, hair and vagina.

    Dusting powder for prevention of athelets feet and ringworm of skin folds.

    Cutaneous candidiasis.

    Otomycosis, fungal infections of external ear.

    Active ingredients: Clotrimazole
    Unit description, dosagePrice, USD
    KadeFungin 3 20 mg/1 g x 20 g

    List of kadefungin 3 brand and generic drugs

    KadeFungin 3 / 6 Kombi-Packung
    Cream; Vaginal; Clotrimazole 2% / Tablet; Vaginal; Clotrimazole
    Kamestin
    Kamestin 100 mg Tablet$ 0.07
    Kamicin (Hongkong)
    Kamicin 100 mg x 10's
    Kamicin 100 mg x 1,000's
    Tablets; Vaginal; Clotrimazole 100 mg
    Kanamazole 1%
    Kandicide
    Kandicide 15 gm Cream$ 0.03
    Kandicide B
    Kandicide B 15 gm Cream$ 0.03
    Kanezin (Taiwan)
    Kanezin 100 mg x 60's
    Kanis (Bangladesh)
    Kansel B
    Kansel B Skin 10 gm Cream$ 0.56
    Kansen (Serbia)
    Kemeizuo - Aoyipollen (China)
    Kenet (Thailand)
    Kenet 0.1 g x 12 x 6's
    Kenet 0.5 g x 12's
    Kinasten
    Klamacin (Thailand)
    Klamacin 100 mg x 6's
    Klomazole (Argentina)
    Klot V
    Klot V 100 mg Tablet$ 0.12
    Klotim B
    Klotim B Skin 15 gm Cream$ 0.67
    Klotricid
    Klotrimasool GSK (Estonia)
    Klotrimazol (Latvia, Norway)
    Klotrimazol Medana (Latvia)
    Klotrimazol Mylan (Sweden)
    Klotrimazolis (Lithuania)
    Konifungil
    Kotozole (Japan)
    Kranos (Indonesia)
    Kranos 10 mg/1 g x 5 g x 1's$ 0.78
    KREMA-ROSA
    Kundo V VG
    Kundo V VG Vaginal Pessary Pessary$ 0.13
    KUNDO-V (India)
    100 mg x 6's$ 0.76
    Kundo-V 100mg VAG-TAB / 6$ 0.76
    L.B.C. (India)
    L.B.C. Chloramphenicol 5 % w/v,Clotrimazole 1 % w/v,Beclomethasone dipropionate0.025 % w/v, Lignocainehydrochloride 2 % w/v. EAR-DPS / 5ml$ 0.44
    5ml$ 0.44
    Laboterol (Chile)
    Lamazone (Thailand)
    Lamazone 1 % w/w x 10 g
    Lamonte-BG (India)
    Lamonte-BG Clotrimazole 1 % w/w,Beclometasone dipropionate0.025 % w/w, Gentamicin 0.1 %w/w. CRM / 15g$ 0.45
    15g$ 0.45
    Lecibis
    Leozole (India)
    Leozole 1% PWD / 100g
    1 % x 100g

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