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Kazide

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Kazide uses and description

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Kazide - Used for: Treating certain parasitic infections of the intestine.

Kazide is an antiparasitic agent. It works by interfering with the production of certain substances that are needed by the parasite to live.

Kazide is an antiprotozoal agent.

Kazide is used to treat diarrhea in adults and children caused by the protozoa Giardia lamblia. Kazide is also used to treat diarrhea caused by the protozoa Cryptosporidium parvum. These conditions are also sometimes referred to as travelers' diarrhea.

Kazide may also be used for purposes other than those listed in this medication guide.

Pharmacology: Interferes with pyruvate:ferredoxin oxidoreductase enzyme-dependent electron transfer reaction, which is essential to anaerobic energy metabolism.

Indication: Treatment of diarrhea caused by Giardia lamblia or Cryptosporidium parvum.

Kazide is an antifolate containing the pyrrolopyrimidine-based nucleus that exerts its antineoplastic activity by disrupting folate-dependent metabolic processes essential for cell replication. In vitro studies have shown that Kazide inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), all folate-dependent enzymes involved in the de novo biosynthesis of thymidine and purine nucleotides. Kazide is transported into cells by both the reduced folate carrier and membrane folate binding protein transport systems. Once in the cell, Kazide is converted to polyglutamate forms by the enzyme folylpolyglutamate synthetase. The polyglutamate forms are retained in cells and are inhibitors of TS and GARFT. Polyglutamation is a time- and concentration-dependent process that occurs in tumor cells and, to a lesser extent, in normal tissues. Polyglutamated metabolites have an increased intracellular half-life resulting in prolonged drug action in malignant cells.

Oral Giardiasis, Cryptosporidiosis

Adult: 500 mg every 12 hr for 3 days.

Child: 1-3 yr: 100 mg every 12 hr; 4-11 yr: 200 mg every 12 hr; ≥12 yr: 500 mg every 12 hr. All doses to be taken for 3 days.

Indications:

Adult: PO Cryptosporidiosis; Giardiasis 500 mg 12 hrly for 3 days.

Active ingredients: Nitazoxanide
Unit description, dosagePrice, USD

List of kazide brand and generic drugs

Kaside (Peru)
Kidonax
Suspension; Oral; Nitazoxanide 100 mg / 5 ml
Tablet, Dispersible; Oral; Nitazoxanide 200 mg
Tablet; Oral; Nitazoxanide 500 mg
Larvisol (Colombia)
Lumbris (Peru)
Mixel (Colombia)
Navigator (United States)
Netazox (India)
Netazox 200mg DT- TAB / 60$ 6.13
Netazox 500mg FC- TAB / 60$ 8.56
Netazox 100mg/5mL SUSP / 30ml$ 0.46
100 mg x 5 mL x 30ml$ 0.46
200 mg x 60's$ 6.13
500 mg x 60's$ 8.56
Netazox 30 ml Suspension$ 0.08
Netazox -OF
Netazox -OF Nitazoxanide 100mg, Ofloxacin50mg/5mL SUSP / 50ml$ 1.10
Netazox -OF Nitazoxanide 500mg, Ofloxacin200mg TAB / 60$ 11.06
Netazox DT
Netazox DT 200 mg Tablet$ 0.09
Netazox FC
Netazox FC 500 mg Tablet$ 0.15
Niazid (Bangladesh)
Nitacol
Nitacol 30 ml Suspension$ 0.06
Nitacure (India)
Nitacure 200mg FC-TAB / 6$ 0.48
Nitacure 500mg FC-TAB / 6$ 0.91
200 mg x 6's$ 0.48
500 mg x 6's$ 0.91
Nitacure 30 ml Syrup$ 0.07
Nitacure 200 mg Tablet$ 0.08
Nitacure 500 mg Tablet$ 0.14
NITACURE SYP (India)
100 mg x 30ml$ 0.44
Nitacure SYP 100mg DRY-SYR / 30ml$ 0.44
Nitanid (Bangladesh, Ecuador)
NITARID (India)
NITARID Capsule/ Tablet / 500mg (6 units)$ 0.83
NITARID Dispersible Tablet / 200mg (6 units)$ 0.59
NITARID Liquid / 10gm per 30ml (30ml units)$ 0.37
200 mg x 6's$ 0.59
500 mg x 6's$ 0.83
30ml$ 0.37
Nitarid 200mg DT-TAB / 6$ 0.59
Nitarid 500mg TAB / 6$ 0.83
Nitarid - DRY-SYR / 30ml$ 0.37
Nitarid 500 mg Tablet$ 0.15
Nitarid 30 ml Syrup$ 0.37

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