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Ketorolac-Grindeks

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Ketorolac-Grindeks uses and description

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Ketorolac-Grindeks - Used for: The short-term (up to 5 days) treatment of moderately severe pain (usually after surgery), alone or in combination with other medicines.

Ketorolac-Grindeks is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes these symptoms.

Ketorolac-Grindeks is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Ketorolac-Grindeks works by reducing hormones that cause inflammation and pain in the body.

Ketorolac-Grindeks is used short-term (5 days or less) to treat moderate to severe pain.

Ketorolac-Grindeks may also be used for other purposes not listed in this medication guide.

Ketorolac-Grindeks is a NSAID, derivative of pyrrolizine-carboxylic acid. This medication has a marked analgesic effect, also has anti-inflammatory and mild antipyretic action. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever.

Ketorolac-Grindeks, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain. It is a peripherally acting analgesic. The biological activity of Ketorolac-Grindeks tromethamine is associated with the S-form. Ketorolac-Grindeks tromethamine possesses no sedative or anxiolytic properties.

Oral Moderate to severe pain

Adult: 10 mg every 4-6 hr. Max: 40 mg/day. Max duration: 7 days.

Elderly: 10 mg every 6-8 hr. Max duration: 7 days. Renal impairment: Contraindicated in moderate to severe impairment. Parenteral Moderate to severe pain

Adult: 60 mg as a single dose via IM inj or 30 mg as a single IV dose. Alternatively, 30 mg every 6 hr via IM or IV admin up to a max of 120 mg daily. Halve the doses in patients weighing <50 kg. Max duration: 2 days; patient should be transferred to oral therapy as soon as possible.

Elderly: 30 mg as a single dose via IM inj or 15 mg as a single IV dose. Alternatively, 15 mg every 6 hr via IM or IV admin up to a max of 60 mg daily. Renal impairment: 30 mg as a single dose via IM inj or 15 mg as a single IV dose. Alternatively, 15 mg every 6 hr via IM or IV admin up to a max of 60 mg daily. Contraindicated in moderate to severe impairment. Ophthalmic Ocular itching associated with seasonal allergic conjunctivitis

Adult: As trometamol: Instil 1 drop of a 0.5% solution into the affected eye(s) 4 times daily. Renal impairment: Contraindicated in moderate to severe impairment. Ophthalmic Prophylaxis and reduction of postoperative ocular inflammation

Adult: As trometamol: Instil 1 drop of a 0.5% solution into the appropriate eye(s) 4 times daily starting 24 hr after surgery. Continue for 2 wk. Renal impairment: Contraindicated in moderate to severe impairment. Ophthalmic Cystoid macular oedema

Adult: As trometamol: Instil 1-2 drops of a 0.5% solution into the appropriate eye(s) every 6-8 hr starting 24 hr before surgery and continue for 3-4 wk after surgery. Renal impairment: Contraindicated in moderate to severe impairment. Ophthalmic Pain and photophobia after incisional refractive surgery

Adult: As trometamol: Instil 1 drop of a 0.5% solution 4 times daily into the operated eye for up to 3 days after surgery. Renal impairment: Contraindicated in moderate to severe impairment. Incompatibility: Y-site incompatibility: Fenoldopam, azithromycin. Syringe incompatibility: Promethazine, hydroxyzine, nalbuphine, haloperidol, prochorperazine edisylate, triethylperazine. Admixture incompatibility: Promethazine, morphine, hydroxyzine, meperidine.

Oral Short-term management of moderate to severe postoperative pain

Adult: As trometamol: 10 mg every 4-6 hr. Max: 40 mg/day. Max duration: 7 days.

Elderly: 10 mg every 6-8 hr. Max: 40 mg/day. Max duration: 7 days. Renal impairment: Max: 40 mg/day. Parenteral Short-term management of moderate to severe postoperative pain

Adult: As trometamol: 10 mg IM/IV followed by 10-30 mg every 4-6 hr if necessary. Max: 90 mg/day (60 mg/day in patients weighing <50 kg).

Elderly: Max: 60 mg/day. Renal impairment: Mild impairment: Max: 60 mg/day. Ophthalmic Ocular itching associated with seasonal allergic conjunctivitis

Adult: As trometamol: Instil 1 drop of a 0.5% solution into the affected eye/s 4 times daily. Ophthalmic Prevention and relief of postoperative eye inflammation

Adult: As trometamol: Instil 1 drop of a 0.5% solution into the appropriate eye/s 4 times daily starting 24 hr after surgery. Continue for 2 wk. Ophthalmic Prevention and relief of postoperative cystoid macular oedema associated with cataract extraction

Adult: As trometamol: Instil 1-2 drops of a 0.5% solution into the appropriate eye/s every 6-8 hr starting 24 hr before surgery and continue for 3-4 wk after surgery. Ophthalmic Active treatment of chronic aphakic or pseudophakic cystoid macular oedema

Adult: As trometamol: Instil 1-2 drops of a 0.5% solution into the affected eye/s 4 times daily for 2-3 mth. Ophthalmic Reduction of ocular pain and photophobia in patients undergoing incisional refractive surgery

Adult: As trometamol: Instil 1 drop of a 0.5% solution 4 times daily into the operated eye for up to 3 days after surgery.

Oral Moderate to severe pain

Adult: 10 mg every 4-6 hr. Max: 40 mg/day. Max duration: 7 days.

Elderly: 10 mg every 6-8 hr. Max duration: 7 days. Renal impairment: Contraindicated in moderate to severe impairment. Parenteral Moderate to severe pain

Adult: 60 mg as a single dose via IM inj or 30 mg as a single IV dose. Alternatively, 30 mg every 6 hr via IM or IV admin up to a max of 120 mg daily. Halve the doses in patients weighing <50 kg. Max duration: 2 days; patient should be transferred to oral therapy as soon as possible.

Elderly: 30 mg as a single dose via IM inj or 15 mg as a single IV dose. Alternatively, 15 mg every 6 hr via IM or IV admin up to a max of 60 mg daily. Renal impairment: 30 mg as a single dose via IM inj or 15 mg as a single IV dose. Alternatively, 15 mg every 6 hr via IM or IV admin up to a max of 60 mg daily. Contraindicated in moderate to severe impairment. Ophthalmic Ocular itching associated with seasonal allergic conjunctivitis

Adult: As trometamol: Instil 1 drop of a 0.5% solution into the affected eye(s) 4 times daily. Renal impairment: Contraindicated in moderate to severe impairment. Ophthalmic Prophylaxis and reduction of postoperative ocular inflammation

Adult: As trometamol: Instil 1 drop of a 0.5% solution into the appropriate eye(s) 4 times daily starting 24 hr after surgery. Continue for 2 wk. Renal impairment: Contraindicated in moderate to severe impairment. Ophthalmic Cystoid macular oedema

Adult: As trometamol: Instil 1-2 drops of a 0.5% solution into the appropriate eye(s) every 6-8 hr starting 24 hr before surgery and continue for 3-4 wk after surgery. Renal impairment: Contraindicated in moderate to severe impairment. Ophthalmic Pain and photophobia after incisional refractive surgery

Adult: As trometamol: Instil 1 drop of a 0.5% solution 4 times daily into the operated eye for up to 3 days after surgery. Renal impairment: Contraindicated in moderate to severe impairment. Special Populations: Renal impairment: Max dose for parenteral admin is 60 mg/day. Incompatibility: Y-site incompatibility: Fenoldopam, azithromycin. Syringe incompatibility: Promethazine, hydroxyzine, nalbuphine, haloperidol, prochorperazine edisylate, triethylperazine. Admixture incompatibility: Promethazine, morphine, hydroxyzine, meperidine.

Indications:

Adult: PO Moderate to severe pain 10 mg 4-6 hrly. Max: 40 mg/day. Max duration: 7 days. IV/IM Moderate to severe pain 60 mg via IM inj or 30 mg via IV inj. Ophth Ocular itching As 0.5% soln: Instill 1 drop 4 times/day. Post-op eye inflammation As 0.5% soln: Instill 1 drop 4 times/day for 2 wk, starting 24 hr after surgery for 2 wk. Cystoid macular oedema As 0.5% soln: Instill 1-2 drops 6-8 hrly starting 24 hr before surgery, continue for 3-4 wk after surgery. Pain and photophobia after incisional refractive surgery As 0.5% soln: Instill 1 drop 4 times/day for up to 3 days after surgery.

Active ingredients: Ketorolac
Unit description, dosagePrice, USD

List of ketorolac-grindeks brand and generic drugs

Ketorolac Tromethamine Sandoz (Canada)
Ketorolaco (Chile)
Injectable; Injection; Ketorolac Tromethamine 15 mg / ml
Injectable; Injection; Ketorolac Tromethamine 30 mg / ml
Tablet; Oral; Ketorolac Tromethamine 10 mg
Tablets; Oral; Ketorolac Tromethamine 10 mg
Ketorolaco Farmindustria (Peru)
Ketorolaco Farvet (Peru)
Ketorolaco G&R (Peru)
Ketorolaco Gen-Far (Peru)
Ketorolaco Genfar (Colombia, Ecuador, Peru)
Ketorolaco Hersil (Peru)
Ketorolaco Induquimica (Peru)
Ketorolaco Infarmasa (Peru)
Ketorolaco Iqfarma (Peru)
Ketorolaco L.CH. (Chile)
Ketorolaco Marfan (Peru)
Ketorolaco Medifarma (Peru)
Ketorolaco Naturgen (Peru)
Ketorolaco Pasteur (Chile)
Ketorolaco Perugen (Peru)
Ketorolaco Trometamina (Peru)
Ketorolaco Trometamina Dany (Peru)
Ketorolaco Trometamol (Chile)
Ketorolaco Trometamol Abax (Spain)
Ketorolaco Trometamol Biosano (Chile)
Ketorolaco Trometamol Combino Pharm (Spain)
Ketorolaco Trometamol Domac (Spain)
Ketorolaco Trometamol Lesvi (Spain)
Ketorolaco Trometamol Mintlab (Chile)
Ketorolaco Trometamol Normon (Spain)
Ketorolaco Trometamol Sanderson (Chile)
KetoVision (Germany)
Ketrodol (Georgia, Turkey)
KETROL (India)
30 mg x 1's$ 0.29
Ketrol 30mg AMP / 1$ 0.29
Ketrox
Ketrox 10mg TAB / 10x10$ 5.93
Ketzy (Georgia)
10ml$ 0.72
Ketzy - EYE DPS / 10ml$ 0.72
Ketzy Eye 10 ml Drop$ 0.72
Ketzy 10 mg Tablet$ 0.05
Kevindol (Italy)
Keytrate
Keytrate 10mg TAB / 10x10$ 5.93

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