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LUPIBOSE

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LUPIBOSE uses and description

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LUPIBOSE - Used for: Treating high blood pressure in the lungs (pulmonary arterial hypertension).

LUPIBOSE is an endothelin receptor antagonist. It works by blocking a certain substance in the lungs, which helps to decrease blood pressure in the lungs.

LUPIBOSE prevents thickening of the blood vessels, especially those in the lungs and heart. LUPIBOSE also lowers blood pressure in your lungs, helping your heart pump blood more efficiently.

LUPIBOSE is used to treat pulmonary arterial hypertension (PAH). It improves your ability to exercise and prevents your condition from getting worse.

LUPIBOSE may also be used for other purposes not listed in this medication guide.

Pharmacology: Antagonizes endothelin receptor by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle.

Indication: Treatment of pulmonary arterial hypertension (WHO group 1) to improve exercise ability and decrease the rate of clinical worsening.

Unlabeled Uses

Prevention of digital ulcers in systemic sclerosis; prevention of Raynaud phenomenon.

LUPIBOSE belongs to a class of drugs known as endothelin receptor antagonists (ERAs). Patients with PAH have elevated levels of endothelin, a potent blood vessel constrictor, in their plasma and lung tissue. LUPIBOSE blocks the binding of endothelin to its receptors, thereby negating endothelin's deleterious effects.

Active ingredients: bosentan
Unit description, dosagePrice, USD
62.5 mg x 10's$ 21.30
125 mg x 10's$ 35.19

List of lupibose brand and generic drugs

Bosentan (Australia, Austria, Belgium, Canada, Czech Republic, Denmark, Finland, France, Germany, Hungary, Iceland, Ireland, Israel, Italy, Japan, Luxembourg, Netherlands, New Zealand, Norway, Singapore, Slovakia, Slovenia, Spain, Sweden, Switzerland, Taiwan, Thailand, Turkey, United Kingdom, United States)
BOSENTAS (India)
62.5 mg x 10's$ 12.78
125 mg x 10's$ 21.11
Bosentas FC
Bosentas FC 62.5 mg Tablet$ 1.28
Bosentas FC 125 mg Tablet$ 3.52
Tracleer (Australia, Austria, Belgium, Canada, Czech Republic, Denmark, Finland, France, Germany, Hungary, Iceland, Ireland, Israel, Italy, Japan, Luxembourg, Netherlands, New Zealand, Norway, Singapore, Slovakia, Slovenia, Spain, Sweden, Switzerland, Taiwan, Thailand, Turkey, United Kingdom, United States)
Tablet, Film-Coated; Oral; Bosentan Monohydrate 62.5 mg
Tablet, Film-Coated; Oral; Bosentan Monohydrate 125 mg
Tablet; Oral; Bosentan Monohydrate 62.5 mg
Tablet; Oral; Bosentan Monohydrate 125 mg
Tracleer 62.5 mg x 60's
Tracleer 125 mg x 60's
Tracleer (bosentan) 125mg film-coated tablets (United Kingdom)
Tracleer (bosentan) 62.5mg film-coated tablets (United Kingdom)
Usenta (Chile)
 
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