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Levonorgestrel

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Levonorgestrel uses and description

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Levonorgestrel - Levonorgestrel is a female hormone. This hormone can cause changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Levonorgestrel intrauterine system is a plastic device that contains the hormone levonorgestrel. This device is placed in the uterus where it slowly releases the hormone to prevent pregnancy for up to 5 years. Levonorgestrel intrauterine system is meant for use in a woman who has had at least one child and is in a stable sexual relationship with someone who has no other sexual partners.

Levonorgestrel intrauterine system is also used in women who have heavy menstrual bleeding and choose to use an intrauterine form of birth control.

Levonorgestrel is a progestin hormone and does not contain estrogen. The intrauterine device releases Levonorgestrel into the uterus, but only small amounts of the hormone reach your blood stream.

Levonorgestrel intrauterine system may also be used for other purposes not listed in this medication guide.

Pharmacology: Levonorgestrel, as contraception, is a progestogen that causes thickening of cervical mucus, inhibition of sperm capacitation or survival, and alteration of the endometrium. Levonorgestrel, as an emergency contraceptive, prevents ovulation or fertilization by altering tubal transport of sperm and/or ova, as well as inhibiting implantation by altering the endometrium.

Indication: Prevention of pregnancy, treatment of heavy menstrual bleeding for women who choose to use intrauterine contraception (intrauterine); emergency contraceptive (oral).

Levonorgestrel is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Levonorgestrel tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.

Oral Contraception

Adult: Monotherapy: 30 or 37.5 mcg daily. Monophasic combined oral contraceptive (COC): 150-250 mcg daily. Triphasic COC: 50-125 mcg daily. Oral Emergency contraception

Adult: 1.5 mg as soon as possible or within 72 hr of coitus. Alternatively, 750 mcg as soon as possible or within 72 hr of coitus followed by a 2nd dose 12 hr later. Another regimen combines Levonorgestrel 500 mcg and ethinylestradiol 100 mcg; may be given within 72 hr of coitus followed by a 2nd dose 12 hr later. Oral Menopausal hormone replacement therapy

Adult: As progestogenic component: 75-250 mcg for 10-12 days of a 28-day cycle. Subcutaneous Contraception

Adult: Insert 6 implants (36 mg/implant) under the skin within the first 7 days of the menstrual cycle and replace at intervals of up to 5 yr. Intrauterine Contraception

Adult: 52 mg released at an initial rate of 20 mcg/day. System is effective for up to 5 yr. Intrauterine Menorrhagia

Adult: 52 mg released at an initial rate of 20 mcg/day. System is effective for up to 5 yr. Transdermal Menopausal hormone replacement therapy

Adult: As combined transdermal patch (releases 10 mcg/24 hr with an oestrogen): Apply once wkly for 2 wk of a 4-wk cycle. Alternatively, a patch releasing 7 or 15 mcg/24 hr with an oestrogen is applied once wkly for continuous HRT.

Indications:

Adult: PO Contraception Monotherapy: 30 or 37.5 mcg/day. Monophasic combined oral contraceptive (COC): 150-250 mcg/day. Triphasic COC: 50-125 mcg/day. Emergency contraception 1.5 mg w/in 72 hr of coitus or 750 mcg immediately or w/in 72 hr of coitus, then a 2nd dose 12 hr later. Menopausal HRT As progestogenic component: 75-250 mcg/day for 10-12 days of 28-day cycle. SC Contraception Insert 6 implants (36 mg/implant) under the skin w/in the 1st 7 days of the menstrual cycle, replace 5 yrly. Intrauterine Contraception; Menorrhagia 52 mg released at an initial rate of 20 mcg/day. Replace after 5 yr. Trandermal Menopausal HRT As combined transdermal patch (10 mcg/24 hr w/ an oestrogen): Apply once wkly for 2 wk for a 4-wk cycle. As combined transdermal patch (7 or 15 mcg/24 hr w/ an oestrogen): Apply once wkly for continuous HRT.

Oral Contraception

Adult: Monotherapy: 30 or 37.5 mcg daily. Monophasic combined oral contraceptive (COC): 150-250 mcg daily. Triphasic COC: 50-125 mcg daily. Oral Emergency contraception

Adult: 1.5 mg as soon as possible or within 72 hr of coitus. Alternatively, 750 mcg as soon as possible or within 72 hr of coitus followed by a 2nd dose 12 hr later. Another regimen combines Levonorgestrel 500 mcg and ethinylestradiol 100 mcg; may be given within 72 hr of coitus followed by a 2nd dose 12 hr later. Oral Menopausal HRT

Adult: As progestogenic component: 75-250 mcg for 10-12 days of a 28-day cycle. Subcutaneous Contraception

Adult: Insert 6 implants (36 mg/implant) under the skin within the first 7 days of the menstrual cycle and replace at intervals of up to 5 yr. Transdermal Menopausal HRT

Adult: As combined transdermal patch (releases 10 mcg/24 hr with an oestrogen): Apply once wkly for 2 wk of a 4-wk cycle. Alternatively, a patch releasing 7 or 15 mcg/24 hr with an oestrogen is applied once wkly for continuous HRT. Intrauterine Contraception

Adult: 52 mg released at an initial rate of 20 mcg/day. System is effective for up to 5 yr. Intrauterine Menorrhagia

Adult: 52 mg released at an initial rate of 20 mcg/day. System is effective for up to 5 yr.

Active ingredients: Levonorgestrel
Unit description, dosagePrice, USD
Tablet; Oral; Levonorgestrel 0.03 mg
Tablet; Oral; Levonorgestrel 1.5 mg
Implant; Implantation; Levonorgestrel 75 mg
Mirena system$ 843.66
Mirena System 52 mg Insert$ 363.54
Nordette (28) 28 0.15-30 mg-mcg tablet Disp Pack$ 79.32
Plan b one-step 1.5 mg tablet$ 40.62
Next choice 0.75 mg tablet$ 36.56
Levora 0.15/30 (28) 28 0.15-30 mg-mcg tablet Disp Pack$ 32.99
Trivora (28) 28 tablet Box$ 29.99
Plan b 0.75 mg tablet$ 15.65
Nordette-28 tablet$ 2.75
Nordette-8 tablet$ 2.39
Levlen 28 tablet$ 1.30
Tri-levlen 28 tablet$ 1.25
Levora-28 tablet$ 1.10
Trivora-28 tablet$ 0.98
Acidophilus 10 bu/gm granules$ 0.60

List of levonorgestrel brand and generic drugs

Levonelle One Step (United Kingdom)
Tablet; Oral; Levonorgestrel 1.5 mg
Levonorgestrel L.CH. (Chile)
Levonorgestrel Perrigo (United States)
Levonorgestrel Pharma Genexx (Chile)
Levonorgestrel Watson (United States)
Levonova (Iceland)
Levora-21
Levora-28
Levostrel (Taiwan)
Levostrel 750 mcg
Libelle (Colombia)
Madonna (Malaysia)
Madonna 0.75 mg x 2's
Malloside
Me (Malaysia)
Me 0.75 mg x 2's
Medonor (Vietnam)
Medonor 0.75 mg x 1 Blister 2 Tablet
Microgest ED
Microgynon 28
Microgynon-30 (Vietnam)
Microgynon-30 1 Blister 21 Tablet
Microlut (Argentina, Australia, Belgium, Colombia, Dominican Republic, Germany, Indonesia, Ireland, Luxembourg, Mexico, New Zealand, Russian Federation)
Tablet, Sugar-Coated; Oral; Levonorgestrel 0.03 mg
Microlut 0.03 mg x 30 mcg x 35's$ 2.00
Microlution
Microluton (Finland)
Microval (Chile, France, Luxembourg, South Africa, Tunisia, Venezuela)
Tablet, Sugar-Coated; Oral; Levonorgestrel 0.03 mg
Microval 10 mg x 1 hoäp
Microval 20 mg x 1 hoäp
Mikro (Lithuania)
Mikro-30
Dragee; Oral; Levonorgestrel 0.03 mg
Minivlar
Minivlar 30
Monofeme 28
MPILL (India)
1.5 mg x 1's$ 1.46
Mpill 1.5mg TAB / 1$ 1.46
No Chance
No Chance 1.5 mg Tablet$ 1.33
No Chance 200 mg Tablet$ 5.54
No will
No will 1.5 mg Tablet$ 1.39
Nofear 72
Nofear 72 1.5 mg Tablet$ 1.46
NOFEAR-72 (India)
1.5 mg x 1's$ 1.46
Nofear-72 1.5mg TAB / 1$ 1.46
Nordette 21
Nordette 28
Norgeal
Norgeston (United Kingdom)
Tablet, Sugar-Coated; Oral; Levonorgestrel 30 mcg
Norgestrel Max (Argentina)

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