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Liquichlor

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Liquichlor uses and description

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Liquichlor consists of Prednisolone, Squalene, Chloramphenicol, Tetracaine.

Prednisolone - Liquichlor (Prednisolone) is in a class of drugs called steroids. Liquichlor (Prednisolone) prevents the release of substances in the body that cause inflammation.

Liquichlor (Prednisolone) is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.

Liquichlor (Prednisolone) may also be used for other purposes not listed in this medication guide.

Pharmacology: Intermediate-acting glucocorticoid that depresses formation, release, and activity of endogenous mediators of inflammation, including prostaglandins, kinins, histamine, liposomal enzymes, and complement system. Also modifies body\'s immune response.

Indication: Oral

Allergic conditions; collagen diseases (eg, systemic lupus erythematous, acute rheumatic carditis); dermatologic diseases; edematous states; endocrine conditions; GI diseases; hematologic diseases; neoplastic conditions; neoplastic diseases; nervous system conditions (eg, acute exacerbations of multiple sclerosis); ophthalmic conditions; conditions related to organ transplantation; pulmonary disease (eg, asthma); renal condition (eg, nephrotic syndrome); rheumatologic conditions; specific infectious diseases including trichinosis with neurologic or myocardial involvement, tuberculous meningitis with subarachnoid block or impending block when used concomitantly with appropriate antituberculous chemotherapy; tuberculosis with pleural or pericardial effusion.

Ophthalmic

Treatment of steroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe; treatment of mild to moderate noninfectious allergic and inflammatory disorders of the lid, conjunctiva, cornea, and sclera, including chemical and thermal burns ( Pred Mild only)

Liquichlor (Prednisolone) is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) inhibits the activity of phospholipase A2 which leads to suppression of the synthesis of prostaglandins and leukotrienes. This medication inhibits the release of COX (especially COX-2), which also helps reduce the production of prostaglandins.

Liquichlor (Prednisolone) reduces the number of circulating lymphocytes (T-and B-cells), monocytes, eosinophils and basophils as a result of their displacement from the bloodstream into lymphoid tissue; suppresses the formation of antibodies.

Liquichlor (Prednisolone) inhibits the release of pituitary ACTH and beta-lipotropina but it does not reduces the level of circulating beta-endorphin. This drug also inhibits the secretion of TSH and FSH.

Liquichlor (Prednisolone) has a vasoconstrictor effect with direct application to the vessels.

Liquichlor (Prednisolone) has a pronounced dose-dependent effect on the metabolism of carbohydrates, proteins and fats. It stimulates gluconeogenesis, amino acid contributes to the capture of the liver and kidneys and increases the activity of enzymes of gluconeogenesis. In the liver, Liquichlor (Prednisolone) enhances the deposition of glycogen by stimulating the activity of glikogensintetazy and synthesis of glucose from the products of protein metabolism. This medicine increases blood glucose activates the secretion of insulin.

Liquichlor (Prednisolone) inhibits glucose uptake by fat cells that leads to the activation of lipolysis. However, due to an increase in insulin secretion is stimulated lipogenesis which contributes to the accumulation of fat.

Liquichlor (Prednisolone) also has catabolic effects in lymphoid and connective tissue, muscle, adipose tissue, skin, bone tissue. To a lesser extent than hydrocortisone Liquichlor (Prednisolone) affects the processes of water and electrolyte metabolism: promotes the excretion of potassium and calcium, delay in the body of sodium and water. Osteoporosis and Itsenko-Cushing\'s syndrome are the main factors limiting the long-term therapy with corticosteroids. As a result of the catabolic actions it may suppress growth in children.

In high doses prednisone can increase the excitability of brain tissue and contributes to lowering the threshold of convulsive readiness. This medication stimulates the excessive production of hydrochloric acid and pepsin in the stomach which leads to the development of peptic ulcers.

When systemic use the therapeutic activity of Liquichlor (Prednisolone) is due to anti-inflammatory, antiallergic, immunosuppressive and antiproliferative action.

For external and local application the therapeutic activity of Liquichlor (Prednisolone) is due to anti-inflammatory, antiallergic and antiexudative (due to vasoconstrictor effect) effect.

As compared with hydrocortisone the anti-inflammatory activity of Liquichlor (Prednisolone) is 4 times greater, the mineralocorticoid activity is 0.6 times smaller.

Liquichlor (Prednisolone) is a synthetic glucocorticoid used as antiinflammatory or immunosuppressive agent. Liquichlor (Prednisolone) is indicated in the treatment of various conditions, including congenital adrenal hyperplasia, psoriatic arthritis, systemic lupus erythematosus, bullous dermatitis herpetiformis, seasonal or perennial allergic rhinitis, allergic corneal marginal ulcers, symptomatic sarcoidosis, idiopathic thrombocytopenic purpura in adults, leukemias and lymphomas in adults, and ulcerative colitis. Glucocorticoids are adrenocortical steroids and cause profound and varied metabolic effects. In addition, they modify the body\'s immune responses to diverse stimuli.

Liquichlor (Prednisolone) (S.Y.) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (S.Y.) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (S.Y.) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (S.Y.) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Kuang Nan) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Kuang Nan) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Kuang Nan) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Kuang Nan) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (L.D.) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (L.D.) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (L.D.) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (L.D.) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Washington) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Washington) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Washington) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Washington) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Chin Teng) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Chin Teng) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Chin Teng) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Chin Teng) belongs to a group of medicines called steroids.

Indications:

Adult: PO Allergic and inflammatory disorders 5-60 mg/day, in 2-4 divided doses. Rheumatoid arthritis Initial: 5-7.5 mg/day, adjust dose if needed. Multiple sclerosis 200 mg/day for 1 wk, then 80 mg every other day for 1 mth. IV/IM Allergic and inflammatory disorders Given as Na phosphate ester: 5-60 mg Liquichlor (Prednisolone) base/day. Ophth Conjunctivitis As 0.12 or 1% acetate susp: Instill 1-2 drops 2-4 times/day. Higher frequency may be used during the initial 24-48 hr. Re-evaluate if there is no improvement after 2 days of treatment. Otic Allergic and inflammatory conditions of the ear As 0.5 or 1% acetate or phosphate soln: Instill as directed. Intra-articular Joint inflammations As acetate: 5-25 mg. As phosphate: 2-30 mg. As terbutate:4-40 mg.

Liquichlor (Prednisolone) (Santong) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Santong) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Santong) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Santong) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (F.S.) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (F.S.) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (F.S.) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (F.S.) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Astar) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Astar) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Astar) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Astar) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (S.S.P.) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (S.S.P.) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (S.S.P.) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (S.S.P.) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Meider) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Meider) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Meider) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Meider) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (L.S.) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (L.S.) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (L.S.) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (L.S.) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Yung Chi) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Yung Chi) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Yung Chi) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Yung Chi) belongs to a group of medicines called steroids.

Oral Allergic and inflammatory disorders

Adult: 5-60 mg daily, usually given in 2-4 divided doses. Usual maintenance dose range: 2.5-15 mg daily. Withdrawal should be gradual after long-term therapy.

Child: 1 mth-18 yr: For autoimmune inflammatory disorders: Initially, 1-2 mg/kg once daily, may reduce dose gradually after a few days if needed. Max: 60 mg daily. For autoimmune hepatitis: Initially, 2 mg/kg once daily, then reduce to minimum effective dose. Max: 40 mg daily. Oral Poorly controlled, moderate to severe asthma

Adult: For patients with at least 2 exacerbations/yr requiring oral corticosteroids: 40-60 mg daily in 1-2 divided doses; usually given as a short course treatment over 3-10 days until symptom resolution and patient achieves a peak expiratory flow (PEF) of at least 80% of his or her personal best. May be used with maintenance dosages of inhaled corticosteroid and a long-acting inhaled β 2 -agonist bronchodilator.

Child: For patients with >3 exacerbations/yr in children ≤4 yr or at least 2 exacerbations/yr in children 5-11 yr: 1-2 mg/kg daily for 3-5 days may be used with existing asthma treatment, dose may be given in 1-2 divided doses. Max: 60 mg daily. Oral Nephrotic syndrome

Child: 1 mth-18 yr: Initially, 60 mg/m 2 (max: 80 mg) once daily for 4 wk until urine is protein-free followed by 40 mg/m 2 every other day for 4 wk then withdraw dose gradually. For prevention of relapse: 0.5-1 mg/kg once daily every other day for 3-6 mth. Oral Rheumatoid arthritis

Adult: Initially, 5-7.5 mg daily adjusted as necessary.

Elderly: 5 mg daily. Oral Multiple sclerosis

Adult: 200 mg daily for 1 wk followed by 80 mg every other day for 1 mth. Oral Infantile spasms

Child: 1 mth-2 yr: Initially, 10 mg 4 times daily for 14 days; increase to 20 mg 3 times daily for 7 days if seizures are not controlled after 7 days; reduce dose slowly over 15 days until therapy is stopped. For patients taking 40 mg daily, reduce dose in steps of 10 mg every 5 days, then stop; patients taking 60 mg daily, reduce dose to 40 mg daily for 5 days, then 20 mg daily for 5 days, then 10 mg daily for 5 days, then stop. Oral Idiopathic thrombocytopenic purpura

Child: 1-10 yr: 1-2 mg/kg daily (max: 14 days) or 4 mg/kg daily (max: 4 days). Parenteral Allergic and inflammatory disorders

Adult: Given as sodium phosphate ester: 5-60 mg Liquichlor (Prednisolone) base daily IV inj/infusion or IM. Dose to be individualised based on the severity of the condition and patient\'s response. Intra-articular Joint inflammations

Adult: 5-25 mg (as acetate) or 2-30 mg (as phosphate) or 4-40 mg (as terbutate). The phosphate and tebutate may also be given intralesional or injected into soft tissue. Ophthalmic Conjunctivitis

Adult: As 1% acetate suspension or 0.12% acetate suspension: Instill 1-2 drops into the affected eye(s) 2-4 times daily. Higher frequency may be used during the initial 24-48 hr, if needed. Re-evaluate if there is no improvement after 2 days of treatment. Otic/Aural Allergic and inflammatory conditions of the ear

Adult: As acetate or phosphate: 0.5 or 1% drops. Special Populations: May need to increase dose in patients with hyperthyroidism to achieve therapeutic effects.

Liquichlor (Prednisolone) (Update) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Update) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Update) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Update) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (VPP) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (VPP) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (VPP) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (VPP) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Daw Jih) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Daw Jih) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Daw Jih) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Daw Jih) belongs to a group of medicines called steroids.

Oral Suppression of allergic and inflammatory responses, bronchial asthma, severe dermatological reactions

Adult: 2.5-60 mg daily, as a single daily dose or as a double dose on alternate days. Oral Acute asthma

Child: 1-2 mg/kg once daily for 3-5 days. Max dose: 40 mg daily Oral As anti-inflammatory or immunosuppressant

Child: 1 mth-18 yr: initially 2 mg/kg once daily, then adjust to the lowest effective dose. Max dose: 40 mg daily. Oral Nephrotic syndrome

Child: Initially, 2 mg/kg daily either as a single dose or tid until urine is protein-free for 3 consecutive days, followed by 1.5 mg/kg every other day for 4 wk. Maintenance dose: 0.5-1 mg/kg/day on alternate days for 3-6 mth. Oral Rheumatoid arthritis

Adult: Initially, 5-7.5 mg daily adjusted as necessary.

Elderly: 5 mg daily. Oral Multiple sclerosis

Adult: 200 mg daily for 1 wk followed by 80 mg every other day for 1 mth. Parenteral Suppression of allergic and inflammatory responses, bronchial asthma, severe dermatological reactions

Adult: As sodium phosphate ester: 4-60 mg daily IV inj/infusion or IM. As aqueous susp of Liquichlor (Prednisolone) acetate: 25-100 mg 1-2 times wkly, given via IM inj. Ophthalmic Conjunctivitis

Adult: As 1% acetate suspension or 0.12% acetate suspension: Instill 1-2 drops into the affected eye(s) 2-4 times daily. Higher frequency may be used during the initial 24-48 hr, if needed. Re-evaluate if there is no improvement after 2 days of treatment. Otic/Aural Allergic and inflammatory conditions of the ear

Adult: As acetate or phosphate: 0.5 or 1% drops. Intra-articular Joint inflammations

Adult: 5-25 mg (as acetate) or 2-30 mg (as phosphate) or 4-40 mg (as terbutate). The phosphate and tebutate may also be given intralesional or injected into soft tissue. Special Populations: May need to increase dose in patients with hyperthyroidism to achieve therapeutic effects.

Liquichlor (Prednisolone) (Chin Tien) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Chin Tien) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Chin Tien) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Chin Tien) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Gentle) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Gentle) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Gentle) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Gentle) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Y.Y.) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Y.Y.) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Y.Y.) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Y.Y.) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Weal-Chance) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Weal-Chance) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Weal-Chance) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Weal-Chance) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Yu Sheng) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Yu Sheng) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Yu Sheng) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Yu Sheng) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Yung Shin) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Yung Shin) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Yung Shin) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Yung Shin) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (Chen Ta) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Chen Ta) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Chen Ta) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Chen Ta) belongs to a group of medicines called steroids.

Oral Allergic and inflammatory disorders

Adult: 5-60 mg daily in 2-4 divided doses.

Maintenance: 2.5-15 mg daily. Withdrawal should be gradual after long-term therapy.

Child: 1 mth-18 yr: Autoimmune inflammatory disorders: Initially, 1-2 mg/kg once daily; may reduce dose gradually after a few days if needed. Max: 60 mg daily. Autoimmune hepatitis: Initially, 2 mg/kg once daily, then reduce to minimum effective dose. Max: 40 mg daily. Oral Poorly controlled, moderate to severe asthma

Adult: Patients with at least 2 exacerbations/yr requiring oral corticosteroids: 40-60 mg daily in 1-2 divided doses; usually given as a short course treatment over 3-10 days until symptom resolution and patient achieves a peak expiratory flow (PEF) of at least 80% of his or her personal best. May be used with maintenance dosages of inhaled corticosteroid and a long-acting inhaled β 2 -agonist bronchodilator.

Child: Patients with >3 exacerbations/yr in children ≤4 yr or at least 2 exacerbations/yr in children 5-11 yr: 1-2 mg/kg daily for 3-5 days may be used with existing asthma treatment; dose may be given in 1-2 divided doses. Max: 60 mg daily. Oral Nephrotic syndrome

Child: 1 mth-18 yr: Initially, 60 mg/m 2 (max: 80 mg) once daily for 4 wk until urine is protein-free followed by 40 mg/m 2 every other day for 4 wk, then withdraw dose gradually. Prevention of relapse: 0.5-1 mg/kg once daily every other day for 3-6 mth. Oral Rheumatoid arthritis

Adult: Initially, 5-7.5 mg daily, adjusted as necessary.

Elderly: 5 mg daily. Oral Multiple sclerosis

Adult: 200 mg daily for 1 wk followed by 80 mg every other day for 1 mth. Oral Infantile spasms

Child: 1 mth-2 yr: Initially, 10 mg 4 times daily for 14 days; increase to 20 mg 3 times daily for 7 days if seizures are not controlled after 7 days; reduce dose slowly over 15 days until therapy is stopped. For patients taking 40 mg daily, reduce dose in steps of 10 mg every 5 days, then stop; in patients taking 60 mg daily, reduce dose to 40 mg daily for 5 days, then 20 mg daily for 5 days, then 10 mg daily for 5 days, then stop. Oral Idiopathic thrombocytopenic purpura

Child: 1-10 yr: 1-2 mg/kg daily (max: 14 days) or 4 mg/kg daily (max: 4 days). Parenteral Allergic and inflammatory disorders

Adult: Given as sodium phosphate ester: 5-60 mg Liquichlor (Prednisolone) base daily IV inj/infusion or IM. Dose to be individualised based on the severity of the condition and patient\'s response. Intra-articular Joint inflammations

Adult: 5-25 mg (as acetate) or 2-30 mg (as phosphate) or 4-40 mg (as terbutate). The phosphate and tebutate may also be given intralesionally or injected into soft tissue. Ophthalmic Conjunctivitis

Adult: As 1% acetate suspension or 0.12% acetate suspension: Instill 1-2 drops into the affected eye(s) 2-4 times daily. Higher frequency may be used during the initial 24-48 hr, if needed. Re-evaluate if there is no improvement after 2 days of treatment. Otic/Aural Allergic and inflammatory conditions of the ear

Adult: As acetate or phosphate: 0.5 or 1% drops. Topical/Cutaneous Rheumatoid arthritis

Adult: As farnesylate: Apply onto the affected area when necessary. Special Populations: May need to increase dose in patients with hyperthyroidism to achieve therapeutic effects.

Liquichlor (Prednisolone) (Winston) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (Winston) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (Winston) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (Winston) belongs to a group of medicines called steroids.

Liquichlor (Prednisolone) (P.J.) helps relieve inflammation and itch that may occur with certain skin problems and allergies. It is also used to relieve pain in arthritic joints, fluid retention in head injuries, treat inflammatory bowel disease and to control asthma. Liquichlor (Prednisolone) (P.J.) may also be used to prevent organ transplant rejection after a transplant. Liquichlor (Prednisolone) (P.J.) may be used for other purposes as decided by your doctor. Liquichlor (Prednisolone) (P.J.) belongs to a group of medicines called steroids.

Allergic conditions; collagen diseases (eg, systemic lupus erythematous, acute rheumatic carditis); dermatologic diseases; edematous states; endocrine conditions; GI diseases; hematologic diseases; neoplastic conditions; neoplastic diseases; nervous system conditions (eg, acute exacerbations of multiple sclerosis); ophthalmic conditions; conditions related to organ transplantation; pulmonary disease (eg, asthma); renal condition (eg, nephrotic syndrome); rheumatologic conditions; specific infectious diseases including trichinosis with neurologic or myocardial involvement, tuberculous meningitis with subarachnoid block or impending block when used concomitantly with appropriate antituberculous chemotherapy; tuberculosis with pleural or pericardial effusion. Treatment of steroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe. Treatment of corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies. Treatment of mild to moderate noninfectious allergic and inflammatory disorders of the lid, conjunctiva, cornea, and sclera (including chemical and thermal burns).

Liquichlor (Prednisolone) Vetoquinol is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) Vetoquinol contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) Vetoquinol has a vasoconstrictor effect with direct application to the vessels.

Liquichlor (Prednisolone) EG Labo is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) EG Labo contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) EG Labo has a vasoconstrictor effect with direct application to the vessels.

Liquichlor (Prednisolone) Sintez is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) Sintez contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) Sintez has a vasoconstrictor effect with direct application to the vessels.

Liquichlor (Prednisolone) Arrow Generiques is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) Arrow Generiques contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) Dominion Veterinary Laboratories is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) Dominion Veterinary Laboratories contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) Teva is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) Teva contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) Teva has a vasoconstrictor effect with direct application to the vessels.

Liquichlor (Prednisolone) Bryntsalov-A is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) Bryntsalov-A contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) Bryntsalov-A has a vasoconstrictor effect with direct application to the vessels.

Liquichlor (Prednisolone) Ferrante is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) Ferrante contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) Ferrante has a vasoconstrictor effect with direct application to the vessels.

Liquichlor (Prednisolone) Amneal Pharmaceuticals is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) Amneal Pharmaceuticals contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) Everylife is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) Everylife contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) Everylife has a vasoconstrictor effect with direct application to the vessels.

Liquichlor (Prednisolone) IVAX is a glucocorticosteroid (GCS). This medication inhibits the function of leukocytes and tissue macrophages. Liquichlor (Prednisolone) restricts the migration of leukocytes in the area of inflammation. This drug violates the ability of macrophages to phagocytosis and the formation of interleukin-1. Liquichlor (Prednisolone) IVAX contributes to the stabilization of lysosomal membranes, thereby reducing the concentration of proteolytic enzymes in inflammation. This medicine decreases capillary permeability caused by histamine release. Liquichlor (Prednisolone) inhibits the activity of fibroblasts and collagen formation.

Liquichlor (Prednisolone) IVAX has a vasoconstrictor effect with direct application to the vessels.

Liquichlor (Prednisolone) inhibits glucose uptake by fat cells that leads to the activation of lipolysis. However, due to an increase in insulin sec

Chloramphenicol - Pharmacology: Interferes with or inhibits microbial protein synthesis.

Indication: Treatment of infections caused by susceptible strains of specific microorganisms; serious systemic infections for which less potentially dangerous drugs are ineffective or contraindicated.

Liquichlor (Chloramphenicol) is a broad-spectrum antibiotic that was derived from the bacterium Streptomyces venezuelae and is now produced synthetically. Liquichlor (Chloramphenicol) is effective against a wide variety of microorganisms, but due to serious side-effects (e.g., damage to the bone marrow, including aplastic anemia) in humans, it is usually reserved for the treatment of serious and life-threatening infections (e.g., typhoid fever). Liquichlor (Chloramphenicol) is bacteriostatic but may be bactericidal in high concentrations or when used against highly susceptible organisms. Liquichlor (Chloramphenicol) stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis.

Oral Bacterial meningitis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Brain abscess

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Granuloma inguinale

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Anthrax

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Listeriosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Gas gangrene

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Whipple's disease

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe systemic infections with Camphylobacter fetus

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Infections caused by H. influenzae

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Ehrlichiosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe gastroenteritis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe melioidosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Plague

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Psittacosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Q fever

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Anaerobic bacterial infections

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Tularaemia

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Ophthalmic Ocular infections

Adult: Instill 1 drop of a 0.5% solution every 2 hr. Increase dosage interval upon improvement. To continue treatment for at least 48 hr after complete healing. Reduce dose once symptoms are controlled or apply a 1% ointment 3-4 times daily. Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Otic/Aural Otitis externa

Adult: Instill 2-3 drops of a 5% solution into the ear bid-tid. Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required.

Liquichlor (Chloramphenicol) is a bacteriostatic antimicrobial. It is considered a prototypical broad-spectrum antibiotic, alongside the tetracyclines.

Liquichlor (Chloramphenicol) is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any indication in developed nations, although it is sometimes used topically for eye infections; nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use. In low-income countries, Liquichlor (Chloramphenicol) is still widely used because it is exceedingly inexpensive and readily available.

The most serious adverse effect associated with Liquichlor (Chloramphenicol) treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and aplastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.

Oral Bacterial meningitis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Anaerobic infections

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Brain abscess

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Granuloma inguinale

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Plague and tularaemia

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Anthrax

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Listeriosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Gas gangrenes

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Whipple's disease

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe systemic infections with Camphylobacter fetus

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Infections due to H. influenzae

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Ehrlichiosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe gastroenteritis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Severe melioidosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Psittacosis

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Oral Q fever

Adult: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections due to moderately resistant organisms. Continue treatment after the patient's temperature has normalised for a further 4 days in rickettsial disease and 8-10 days in typhoid fever.

Child: Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50 mg/kg/day in 4 divided doses increased to 100 mg/kg/day for meningitis or severe infections.

Elderly: Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Ophthalmic Eye infections

Adult: Instill 1 drop of a 0.5% solution every 2 hr. Increase dosage interval upon improvement. To continue treatment for at least 48 hr after complete healing. Reduce dose once symptoms are controlled or apply a 1% ointment 3-4 times daily. Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required. Otic/Aural otitis externa

Adult: Instill 2-3 drops of a 5% solution into the ear bid-tid. Renal impairment: Dose reduction may be required. Hepatic impairment: Dose reduction may be required.

Indications:

Adult: PO Susceptible infections 50 mg/kg/day in 4 divided doses, may increase to 100 mg/kg/day in more severe infections. Ophth Ocular infections As 0.5% soln: Instill 1 drop 2 hrly, then adjust dosage interval upon improvement. Otic Otitis externa As 5% soln: Instill 2-3 drops 2-3 times/day.

Liquichlor (Chloramphenicol) is indicated for the topical treatment of infections due to micro-organisms sensitive to the anti-infective.

Indications: Enteric fever (Typhoid and Para typhoid).

H.

Influenzae meningitis.

Anaerobic infections, intraocular infections, urinary tract infections, conjunctivitis, external ear infections.

Corneal ulcer, bacterial conjunctivitis, trachoma, ocular infections.

Otitis externa, chronic otitis media.

Pre and post antral or mastoid surgery.

Tetracaine - Subarachnoid Spinal anaesthesia

Adult: 1% solution diluted with an equal volume of CSF immediately prior to admin or 5 mg of powder dissolved in 1 ml of CSF and admin slowly at a rate of 1 ml/5 sec. For anaesthesia of perineum: 5 mg. For anaesthesia of perineum and lower extremities: 10 mg. For spinal anaesthesia extending up to the costal margin: 15-20 mg. For low spinal (saddle block) anaesthesia in vaginal delivery: 2-5 mg admin as a hyperbaric solution.

Elderly: Dose reduction may be needed. Ophthalmic Anaesthesia of the eye

Adult: Instil 0.5-1% Liquichlor (Tetracaine) solution or 0.5% ointment. Topical/Cutaneous Topical anaesthesia

Adult: Apply as 1% cream or 0.5% ointment. For percutaneous local anaesthesia before venepuncture or venous cannulation: Apply 4% gel to the centre of the area to be anaesthetised and covered with an occlusive dressing. Remove gel and dressing after 30 minutes for venepuncture and after 45 minutes for venous cannulation.

Subarachnoid Spinal anaesthesia

Adult: 1% solution diluted with an equal volume of CSF immediately prior to admin or 5 mg of powder dissolved in 1 ml of CSF and admin slowly at a rate of 1 ml/5 sec. For anaesthesia of perineum: 5 mg. For anaesthesia of perineum and lower extremities: 10 mg. For spinal anaesthesia extending up to the costal margin: 15-20 mg. For low spinal (saddle block) anaesthesia in vaginal delivery: 2-5 mg admin as a hyperbaric solution.

Elderly: Dose reduction may be needed. Ophthalmic Anaesthesia during ophthalmological procedures

Adult: Instil 0.5-1% Liquichlor (Tetracaine) solution or 0.5% ointment. Topical/Cutaneous Topical anaesthesia

Adult: Apply as 1% cream or 0.5% ointment. Topical/Cutaneous Percutaneous local anaesthetic before venepuncture or venous cannulation

Adult: 4% gel to be applied to centre of area to be anaesthetised and covered with an occlusive dressing. Remove gel and dressing after 30 min for venepuncture and after 45 min for venous cannulation.

Subarachnoid Spinal anaesthesia

Adult: 1% solution diluted with an equal volume of CSF immediately prior to admin or 5 mg of powder dissolved in 1 ml of CSF and admin slowly at a rate of 1 ml/5 sec. For anaesthesia of perineum: 5 mg. For anaesthesia of perineum and lower extremities: 10 mg. For spinal anaesthesia extending up to the costal margin: 15-20 mg. For low spinal (saddle block) anaesthesia in vaginal delivery: 2-5 mg admin as a hyperbaric solution.

Elderly: Dose reduction may be needed. Ophthalmic Anaesthesia of the eye

Adult: Instil 0.5-1% Liquichlor (Tetracaine) solution or 0.5% ointment. Topical/Cutaneous Topical anaesthesia

Adult: Apply as 1% cream or 0.5% ointment. For percutaneous local anaesthesia before venepuncture or venous cannulation: Apply 4% gel to the centre of the area to be anaesthetised and covered with an occlusive dressing. Remove gel and dressing after 30 minutes for venepuncture and after 45 minutes for venous cannulation. Special Populations:

Elderly: May require lower concentrations and/or lower dosages of mucosal-local anesthetics, esp for endoscopic procedures.

Indications:

Adult: Subarachnoid Spinal anesth 1% soln diluted w/ an equal volume of CSF immediately prior to administration and infuse at 1 mL/5 sec. Anesth of perineum: 5 mg. Anesth of perineum and lower extremities: 10 mg. Spinal anesth extending up to the costal margin: 15-20 mg. Low spinal (saddle block) anesth in vag delivery: 2-5 mg as a hyperbaric soln. Ophth Anesth of the eye As 0.5-1% soln or 0.5% oint: Use as directed. Topical Topical anesth As 1% cream or 0.5% oint. For percutaneous local anesth before venepuncture or venous cannulation: Use 4% gel: Apply and cover w/ an occlusive dressing. Remove gel and dressing after 30 mins for venepuncture and after 45 mins for venous cannulation.

Active ingredients: Prednisolone/Squalene/Chloramphenicol/Tetracaine
Unit description, dosagePrice, USD
Liquid; Otic; Chloramphenicol 4.2 mg; Prednisolone 1.7 mg; Squalene 0.21 mg; Tetracaine 4.2 mg / ml

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