Description and uses | Sort by popularity |
Maclofen - Pharmacology: May inhibit transmission of reflexes at spinal level, possibly by action (hyperpolarization) at primary afferent fiber terminals, resulting in relief of muscle spasticity; has CNS depressant properties.
Indication: Oral
Treatment of reversible spasticity resulting from multiple sclerosis. May be of some value in patients with spinal cord injuries and other spinal cord diseases.
Intrathecal
Treatment of severe spasticity of spinal cord origin in patients 4 y and older who are unresponsive to or cannot tolerate oral Maclofen therapy. Used intrathecally in single bolus test doses; chronic use requires implantable pump.
Unlabeled UsesOral
Therapy for trigeminal neuralgia (tic douloureux); tardive dyskinesia; GERD; hiccups; prevention of migraine; Tourette syndrome.
Cerebral palsy spasticity in children; generalized dystonia associated with cerebral palsy.
Used for: Treating severe muscle spasms due to a variety of causes, including brain or spinal cord injuries.
Maclofen is a muscle relaxant and antispastic agent. It reduces the frequency and severity of muscle spasms that occur as a result of neurological disorders, such as multiple sclerosis.
Maclofen is centrally acting muscle relaxant; GABA-receptor agonist. It depresses mono-and polysynaptic reflexes presumably by reducing the release of excitatory amino acids (glutamate and aspartate) from the terminals which occurs as a result of stimulation of presynaptic GABA-receptors. This medication does not affect the transmission of impulses in the nerve-muscle synapses; reduces skeletal muscle tone; has a moderate analgesic effect. |
| Active ingredients: Baclofen |
| Unit description, dosage | Price, USD |
| Maclofen 10 mg | |
| Maclofen 10 mg x Blister pk | |
|
List of interchangeable brands or generic drugs |
| Lyflex (United Kingdom) |
| Solution; Oral; Baclofen 5 mg / 5 ml | |
| Med Baclofen |
| Tablet; Oral; Baclofen 10 mg | |
| Tablet; Oral; Baclofen 20 mg | |
| Tablets; Oral; Baclofen 10 mg | |
| Tablets; Oral; Baclofen 20 mg | |
| Miorel (France, Greece) |
| Capsule; Oral; Thiocolchicoside 4 mg | |
| Injectable; Injection; Thiocolchicoside 2 mg / ml | |
| Mulax (Taiwan) |
| Mulax 10 mg x 500's | |
| Mulax (Orange-flavored sachet) 7 g x 10's | $ 4.08 |
| Muscofen (Taiwan) |
| Muscofen 10 mg | |
| Mylan-Baclofen |
| Tablet; Oral; Baclofen 10 mg | |
| Tablet; Oral; Baclofen 20 mg | |
| Tablets; Oral; Baclofen 10 mg | |
| Tablets; Oral; Baclofen 20 mg | |
| Neurospas (India) |
| NEUROSPAS Capsule/ Tablet / 20mg - 500mg (10 units) | $ 0.22 |
| 100's | $ 2.17 |
| Novo-Baclofen |
| Tablet; Oral; Baclofen 10 mg | |
| Tablet; Oral; Baclofen 20 mg | |
| Tablets; Oral; Baclofen 10 mg | |
| Tablets; Oral; Baclofen 20 mg | |
| Nu-Baclo |
| Tablet; Oral; Baclofen 10 mg | |
| Tablet; Oral; Baclofen 20 mg | |
| Tablets; Oral; Baclofen 10 mg | |
| Tablets; Oral; Baclofen 20 mg | |
| Nu-Baclofen |
| Tablet; Oral; Baclofen 10 mg | |
| Tablet; Oral; Baclofen 20 mg | |
| Tablets; Oral; Baclofen 10 mg | |
| Tablets; Oral; Baclofen 20 mg | |
| Onelaxant (Philippines) |
| Onelaxant-R (Philippines) |
| Onelaxant-R 10 mg x 100's | $ 42.35 |
| Pacifen (New Zealand, Taiwan) |
| Pacifen 10 mg x 50's | |
| Pacifen 25 mg x 50's | |
| Pharmaclofen (Vietnam) |
| Pharmaclofen 10 mg x 1 chai 100 Tablet | |
| Pharmaclofen 10 mg x 1 chai 10 Tablet | |
| PHL-Baclofen |
| Tablet; Oral; Baclofen 10 mg | |
| Tablet; Oral; Baclofen 20 mg | |
| Tablets; Oral; Baclofen 10 mg | |
| Tablets; Oral; Baclofen 20 mg | |
| Pickton (Taiwan) |
| Pickton 10 mg | |
| PMS-Baclofen (Canada, Tunisia) |
| Tablet; Oral; Baclofen 10 mg | |
| Tablet; Oral; Baclofen 20 mg | |
| PMS-Baclofen 10 mg x 1's | |
brands or generic drugs
