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Methergin

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Methergin uses and description

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Methergin - Methergin is a semisynthetic ergot alkaloid and a derivative of ergonovine and is used for the prevention and control of postpartum and post-abortion hemorrhage. In general, the effects of all the ergot alkaloids appear to results from their actions as partial agonists or antagonists at adrenergic, dopaminergic, and tryptaminergic receptors. The spectrum of effects depends on the agent, dosage, species, tissue, and experimental or physiological conditions. All of the alkaloids of ergot significantly increase the motor activity of the uterus. After small doses contractions are increased in force or frequency, or both, but are followed by a normal degree of relaxation. As the dose is increased, contractions become more forceful and prolonged, resting tonus is markedly increased, and sustained contracture can result.

Indication: For the prevention and control of excessive bleeding following vaginal childbirth

Methergin (other names include methylergonovine, methylergobasin, and d-lysergic acid 1-butanolamide) is a synthetic analogue of ergonovine, a psychedelic alkaloid found in ergot, and many species of morning glory. It is a member of the ergoline family and chemically similar to LSD, ergine, ergometrine, and lysergic acid. Due to its oxytocic properties, it has a medical use in obstetrics. According to Jonathan Ott, methylergonovine has LSD-like actions above 2 milligrams. Clinical dosages are ten times lower.

Methergin maleate is marketed under the trade name Methergine.

Active management of the 3rd stage of labour (as a means to promote separation of the placenta and to reduce blood loss). Treatment of uterine atony/haemorrhage during and after the 3rd stage of labour; in association with caesarean section; following abortion. Treatment of subinvolution of the uterus, lochiometra and puerperal bleeding.

Prophylaxis of postpartum haemorrhage. Treatment and prophylaxis of postpartum and postabortal haemorrhage.

Methergin is a blood vessel constrictor and smooth muscle agonist most commonly used to prevent or control excessive bleeding following childbirth and spontaneous or elective abortion. It also causes uterine contractions to aid in expulsion of retained products of conception after a missed abortion (miscarriage in which all or part of the fetus remains in the uterus) and to help deliver the placenta after childbirth

Active ingredients: Methylergometrine
Unit description, dosagePrice, USD
Dragee; Oral; Methylergonovine Maleate 0.125 mg
Drops; Oral; Methylergonovine Maleate 0.25 mg / ml
Injectable; Injection; Methylergonovine Maleate 0.2 mg / ml
Solution; Oral; Methylergonovine Maleate 0.25 mg / ml
Tablet, Film-Coated; Oral; Methylergonovine Maleate 0.125 mg
Tablet; Oral; Methylergonovine Maleate 0.125 mg
METHERGIN Injection / 0.2mg per ml (2x5x1ml units)$ 3.54
METHERGIN Capsule/ Tablet / 0.125mg (10 units)$ 1.69
METHERGIN Capsule/ Tablet / 0.125mg (8x6x10 units)$ 48.44
METHERGIN Capsule/ Tablet / 0.125mg (8x2x10 units)$ 43.75
Methergin 0.2mg/mL AMP / 1$ 0.56
Methergin 0.125mg TAB / 10$ 1.80
Methergin 125 mcg x 30's
Methergin 200 mcg/1 mL x 100's
Methergin 125 mcg x 100's$ 67.66
Methergin (amp) 200 mcg/1 mL x 1 mL x 10's$ 62.23
Methergin 0.125 mg x 30's
Methergin 0.125 mg x 10 x 10's$ 29.74
Methergin 0.2 mg/1 mL x 10's$ 7.90
Methergin 0.2 mg/1 mL x 100's$ 75.25
Methergin 0.2 mg/1 mL x 1 mL x 3 oáng
0.125 mg x 10's$ 1.80
0.2 mg x 1 mL x 1's$ 0.56
Methergin 0.125 mg x 100's

List of methergin brand and generic drugs

Metenarin (Japan)
Methergine (United States)
Injectable; Injection; Methylergonovine Maleate 0.2 mg / ml
Tablet; Oral; Methylergonovine Maleate 0.2 mg
1 milliliter in 1 ampule
100 tablet in 1 bottle
Metherinal (Indonesia)
Metherinal 125 mcg x 10 x 10's$ 3.06
Metherinal 0.2 mg/1 mL x 1 mL x 10's$ 3.57
Metherspan (Bangladesh)
Methin (India)
Methin 0.2mg/mL AMP / 1ml$ 0.32
0.2 mg x 1 mL x 1's$ 0.32
Methovin (Indonesia)
Methovin 0.125 mg x 100's$ 9.20
Methygene
Methygene 125mg TAB / 10$ 1.83
Methygene 0.2mg x 1mL INJ / 1ml$ 0.36
Methylergobrevin (Czech Republic)
Injectable; Injection; Methylergonovine Maleate 0.2 mg / ml
Methylergometrin (Poland, Serbia)
Methylergometrin Spofa (Czech Republic, Slovakia)
Methylergometrin-Rotexmedica (Germany)
Methylergometrine (Turkey)
Methylergometrine Fuji Yakuhin (Japan)
Methylergometrine Maleate F (Japan)
Methylergometrine Maleate Nisshin Seiyaku - Yamagata (Japan)
Methylergometrine Maleate Taiyo (Japan)
Methylergometrine NIHFI (Bulgaria)
Methylergonovine Maleate (United States)
Methylergonovine Maleate Novel (United States)
Methylergonovine Tai Yu (Taiwan)
Metilat (Indonesia)
Metilat 0.125 mg x 10 x 10's$ 16.83
Metiler (Turkey)
Metrol (Ethiopia, Tunisia)
Tablet; Oral; Metoprolol Tartrate 100 mg
Tablet; Oral; Metoprolol Tartrate 50 mg
Tablets; Oral; Metoprolol Tartrate 100 mg
Tablets; Oral; Metoprolol Tartrate 50 mg
Metvell (Indonesia)
Metvell 0.125 mg x 30's$ 4.69
Metvell 0.2 mg/1 mL x 10's$ 5.00
Myomergin (Indonesia)
Myomergin 0.2 mg/1 mL x 10's$ 3.25
NIMETH (India)
0.2 mg x 1 mL x 1's
Nimeth 0.2mg x 1mL AMP / 1
Nugine
Nugine 0.125mg TAB / 10$ 1.30
Partan M (Japan)
Pospargin (Indonesia, Myanmar)
Pospargin 0.125 mg x 10 x 10's$ 4.49
Pospargin 0.2 mg/1 mL x 1 mL x 10's$ 4.79
Pospargin 0.125 mg x 10 Blister x 10 Tablet

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