Myotril - Used for: Controlling certain types of seizures in the treatment of epilepsy and for the treatment of panic disorders. It may also be used for other conditions as determined by your doctor.
Myotril is a benzodiazepine. It works by increasing the activity of a naturally occurring chemical in the brain.
Pharmacology: Potentiates action of GABA, inhibitory neurotransmitter, resulting in increased neuronal inhibition and CNS depression, especially in limbic system and reticular formation.
Indication: Treatment of Lennox-Gastaut syndrome; management of akinetic and myoclonic seizures and absence seizures unresponsive to succinimides; panic disorders.
Treatment of restless legs syndrome, parkinsonian dysarthria, acute manic episodes of bipolar affective disorder, multifocal tic disorders and neuralgias; adjunctive therapy for schizophrenia.
Myotril is an antiepileptic drugs from the group of benzodiazepine derivatives. This medication has a pronounced anticonvulsant and central muscle relaxant, anxiolytic, sedative and hypnotic effects.
Myotril strengthens the inhibitory effect of GABA on the transmission of nerve impulses.
Anxiolytic effects of this drug is due to the influence on the amygdaloid complex of the limbic system and appears in reducing the emotional stress, reduce anxiety, fear, anxiety.
The sedation effects is due to the influence on the reticular formation of the brainstem and nonspecific thalamic nucleus and manifests a decrease in neurotic symptoms (anxiety, fear).
Anticonvulsant effect is realized by increasing presynaptic inhibition.
The central muscle relaxant effect is due to inhibition of spinal polysynaptic afferent inhibitory ways (to a lesser extent and monosynaptic).
It is possibly and direct inhibition of motor nerves and muscle function.
Myotril, a benzodiazepine, is used primarily as an anticonvulsant in the treatment of absence seizures, petit mal variant seizures (Lennox-Gastaut syndrome), akinetic and myoclonic seizures, and nocturnal myoclonus.
Myotril is used to treat epilepsy (also known as seizures or fits). Myotril is also used to treat panic attacks and schizophrenia.
Adult: Initially, 1 mg given at night for 4 nights, gradually increased over 2-4 wk.
Maintenance: 4-8 mg daily. Max: 20 mg/day
Child: 1-5 yr: 250 mcg daily; 5-12 yr: 500 mcg daily. Maintenance (given in 2-4 divided doses): Infants: 0.5-1 mg daily; 1-5 yr: 1-3 mg daily; 5-12 yr: 3-6 mg daily. Max: 200 mcg/kg/day
Elderly: Initially, 500 mcg at night for 4 nights, may gradually increase over 2-4 wk. Hepatic impairment: Dose reduction may be needed. Oral Panic disorder
Adult: Initially, 250 mcg bid, increased after 3 days up to 1 mg daily. Max: 4 mg daily. Hepatic impairment: Dose reduction may be needed. Intravenous Emergency management of status epilepticus
Adult: 1 mg as inj or infusion given over at least 2 min, repeated if necessary.
Child: and infants: 500 mcg as inj or infusion given over at least 2 min, repeated if necessary. Hepatic impairment: Dose reduction may be needed.
Adult: PO Epilepsy Initial: 1 mg/day at night for 4 nights, may increase gradually.
Maintenance: 4-8 mg/day. Max: 20 mg/day. Panic disorder Initial: 250 mcg twice daily. Max: 4 mg/day. IV Emergency treatment of status epilepticus 1 mg as inj or infusion, repeat if needed.
used to control certain types of seizures in the treatment of epilepsy and for the treatment of panic disorders. Clonazepam may also be used for other purposes not listed in this medication guide.