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Nizole uses and description

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Nizole - Nizole is an anti protozoal agent. It is believed that the mechanism of action is associated with DNA damage-sensitive microorganisms. Active against Trichomonas vaginalis, Gardnerella vaginalis, Giardia lamblia, Entamoeba histolytica, and obligate anaerobic bacteria (including Bacteroides spp., Fusobacterium spp.).

Aerobic bacteria are resistant to metronidazole.

In combination with amoxicillin Nizole is active against Helicobacter pylori. It is believed that amoxicillin inhibits the development of resistance of Helicobacter pylori to metronidazole.

Nizole is an antibiotic. It is used to treat dental, lung, skin, vagina, bone and joint infections, infection of the digestive tract and certain sexually transmitted diseases (STD). It is also used together with other medicines for gastric ulcers caused by a type of bacteria known as Helicobacter pylori.

Indications: anaerobic bacterial infections, protozoal infections

Symptomatic TrichomoniasisMetronidazole is indicated for the treatment of symptomatic trichomoniasis in females and males when the presence of thetrichomonad has been confirmed by appropriate laboratory procedures (wet smears and/or cultures).Asymptomatic TrichomoniasisMetronidazole is indicated in the treatment of asymptomatic females when the organism is associated with endocervi-citis, cervicitis, or cervical erosion. Since there is evidence that presence of the trichomonad can interfere with accurate assessment of abnormal cytological smears, additional smears should be performed after eradication of the parasite. Treatment of Asymptomatic Consorts. T. vagi-nalis infection is a venereal disease. Therefore, asymptomatic sexual partners of treated patients should be treated simultaneously if the organism has been found to be present, in order to prevent reinfection of the partner. The decision as to whether to treat an asymptomatic male partner who has a negative culture or one for whom no culture has been attempted is an individual one. In making this decision, it should be noted that there is evidence that a woman may become reinfected if her consort is not treated. Also, since there can be considerable difficulty in isolating the organism from the asymptomatic male carrier, negative smears and cultures cannot be relied upon in this regard. In any event, the consort should be treated with Nizole in cases of reinfection. AmebiasisMetronidazole is indicated in the treatment of acute intestinal amebiasis (amebic dysen-tery)and amebic liver abscess. In amebic liver abscess, Nizole therapy does not obviate the need for aspiration or drainage of pus. Anaerobic Bacterial InfectionsMetronidazole is indicated in the treatment of serious infections caused by susceptible anaerobic bacteria. Indicated surgical procedures should be performed in conjunction with Nizole therapy. In a mixed aerobic and anaerobic infection, antimicrobials appropriate for the treatment of the aerobic infection should be used in addition to Flagyl. In the treatment of most serious anaerobic infections, Nizole I.V. (metronidazole hydrochloride) or Nizole I.V. RTU® (metronidazole) is usually administered initially. This may be followed by oral ther-apy with Nizole (metronidazole) at the discretion of the physician. INTRA-ABDOMINAL INFECTIONS, including peritonitis, intra-abdominal abscess, and liver abscess, caused by Bacteroides species including the B. fragilis group (B. fragilis, B. distasonis,B. ovatus, B. thetaiotaomicron, B. vulgatus), Clostrid-ium species, Eubacterium species, Peptococcus niger, and Peptostreptococcus species. SKIN AND SKIN STRUCTURE INFECTIONS caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcus niger,Peptostreptococcus species, and Fusobacte-rium species. GYNECOLOGIC INFECTIONS, including endo-metritis, endomyometritis, tubo-ovarian abscess, and postsurgical vaginal cuff infection, caused by Bacteroides species including the B. fragilis group, Clostridium species, Peptococcusniger, and Pepto-streptococcus species. BACTERIAL SEPTICEMIA caused by Bacteroides species including the B. fragilis group, and Clos-tridium species. BONE AND JOINT INFECTIONS, as adjunctive therapy, caused by Bacteroides species including the B. fragilis group. CENTRAL NERVOUS SYSTEM (CNS) INFECTIONS, including meningitis and brain abscess, caused by Bacteroides species including the B.fragilis group. LOWER RESPIRATORY TRACT INFECTIONS, including pneumonia, empyema, and lung abscess, caused by Bacteroides species including the B. fragilis group. ENDOCARDITIS caused by Bacteroides species including the B.fragilis group. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Nizole and other antibacterial drugs, Nizole should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Active ingredients: Metronidazole
Unit description, dosagePrice, USD
Nizole 200 mg x 1000's$ 29.80
Tablets; Oral; Metronidazole 200 mg

List of nizole brand and generic drugs

Nof M
Nof M 30 ml Suspension$ 0.08
Nofmet 30 ml Suspension$ 0.08
Nome 30 ml Suspension$ 0.08
Nor-Metrogel (Dominican Republic, El Salvador, Guatemala, Panama)
Noraxin M
Noraxin M 30 ml Suspension$ 0.08
Norbect 30 ml Syrup$ 0.08
Norcem M
Norcem M 30 ml Suspension$ 0.08
Norcimax M
Norcimax M 30 ml Suspension$ 0.11
Nordik M
Nordik M 30 ml Suspension$ 0.08
Norex M
Norex M 30 ml Suspension$ 0.08
Norf M
Norf M 100+100 Tablet$ 0.11
Norfed NM
Norfed NM 30 ml Suspension$ 0.07
Norfix 30 ml Suspension$ 0.08
Norin MZ
Norin MZ 30 ml Suspension$ 0.08
Norin MZ 60 ml Suspension$ 0.06
Norit M
Norit M 30 ml Suspension$ 0.08
Noritate (Canada, Chile, Israel, United States)
Cream; Topical; Metronidazole 1%
Norkin Plus
Norkin Plus 400+400 Tablet$ 0.08
Norlox M
Norlox M 30 ml Suspension$ 0.07
Norluck M
Norluck M 30 ml Suspension$ 0.05
Normez 30 ml Suspension$ 0.08
Normezole 30 ml Suspension$ 0.07
Normin MZ
Normin MZ 30 ml Suspension$ 0.08
Normin MZ 60 ml Suspension$ 0.06
Normogyl 400+600 Tablet$ 0.09
Normogyl 30 ml Suspension$ 0.07
Norosept 30 ml Suspension$ 0.08
Norosol M
Norosol M 30 ml Suspension$ 0.03
Norstene (Philippines)
Norstene (vial) 5 mg/1 mL x 100 mL x 25's
Nortum M
Nortum M 30 ml Suspension$ 0.08
Norwen 30 ml Suspension$ 0.08
Norwin M
Norwin M 30 ml Syrup$ 0.07
Norxizole DT
Norxizole DT 100+100 Tablet$ 0.06
Norzol (Oman)
Suspension; Oral; Metronidazole Benzoate 320 mg / 5 ml
Norzole Forte
Norzole Forte 30 ml Suspension$ 0.09
Notty Kid
Notty Kid 100+100 Tablet$ 0.06
Novazole (Zimbabwe)
Tablet; Oral; Metronidazole 250 mg
Tablets; Oral; Metronidazole 250 mg
Tablet; Oral; Metronidazole 250 mg
Tablets; Oral; Metronidazole 250 mg

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