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Noradox

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Noradox uses and description

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Noradox - Used for: Treating high blood pressure and treating signs and symptoms of benign prostatic hyperplasia (BPH).

Noradox is an alpha-blocker. It works by relaxing muscles in the blood vessels, resulting in lowering of blood pressure. In men with BPH, alpha-blockers work by relaxing muscles around the urethra (the tube that drains urine from the bladder), which improves urinary symptoms.

Noradox is an alpha-adrenergic blocking agent used to treat hypertension and benign prostatic hyperplasia. Accordingly, Noradox is a selective inhibitor of the alpha1 subtype of alpha adrenergic receptors. In the human prostate, Noradox antagonizes phenylephrine (alpha1 agonist)-induced contractions, in vitro, and binds with high affinity to the alpha1c adrenoceptor, which is thought to be the predominant functional type in the prostate. Studies in normal human subjects have shown that Noradox competitively antagonized the pressor effects of phenylephrine (an alpha1 agonist) and the systolic pressor effect of norepinephrine. The antihypertensive effect of Noradox results from a decrease in systemic vascular resistance and the parent compound Noradox is primarily responsible for the antihypertensive activity.

Noradox is used to treat symptoms of an enlarged prostate gland in men. This enlargement of the prostate gland is called Benign Prostate Hypertrophy (BPH). The enlarged prostate gland may cause problems when you pass urine. Noradox relaxes the muscles in the prostate gland and bladder. This helps to improve symptoms such as difficulty in passing urine, slow or interrupted flow of urine, frequent urination and dribbling after passing urine. Noradox may also be used on its own or together with other medicines in the treatment of high blood pressure. Noradox helps to lower the blood pressure by relaxing the blood vessels.

Oral Hypertension

Adult: As mesilate: Initially, 1 mg at bedtime increased after 1-2 wk according to response.

Maintenance: 4 mg once daily. Max: 16 mg daily. Oral Benign prostatic hyperplasia

Adult: As mesilate: Initially, 1 mg once daily at bedtime increased after 1-2 wk; monitor BP after 2-6 hr.

Maintenance: 2-4 mg daily. Max: 8 mg daily.

Indications:

Adult: PO HTN Initial: 1 mg/day at bedtime.

Maintenance: 4 mg once daily. Max: 16 mg/day. Benign prostatic hyperplasia Initial: 1 mg/day at bedtime.

Maintenance: 2-4 mg/day. Max: 8 mg/day.

Oral hypertension

Adult: As mesilate: Initially, 1 mg at bedtime increased after 1-2 wk according to response.

Maintenance: 4 mg once daily. Max: 16 mg daily. Oral Benign prostatic hyperplasia (BPH)

Adult: As mesilate: Initially, 1 mg once daily at bedtime increased after 1-2 wk; monitor BP after 2-6 hr.

Maintenance: 2-4 mg daily. Max: 8 mg daily.

Active ingredients: Doxazosin
Unit description, dosagePrice, USD

List of noradox brand and generic drugs

Mylan-Doxazosin
Tablet; Oral; Doxazosin Mesylate 4 mg
Normothen (Italy)
Novo-Doxazosin
Tablet; Oral; Doxazosin Mesylate 1 mg
Tablet; Oral; Doxazosin Mesylate 2 mg
Tablet; Oral; Doxazosin Mesylate 4 mg
Pencor (Singapore)
Pencor 2 mg x 10 x 10's
Pencor 4 mg x 10 x 10's
Pencor 1 mg x 10 x 10's
Pencor 2 mg x 10 x 10's
Pencor 2 mg x 50 x 10's
Platox M (Japan)
PMS-Doxazosin
Tablet; Oral; Doxazosin Mesylate 1 mg
Tablet; Oral; Doxazosin Mesylate 2 mg
Tablet; Oral; Doxazosin Mesylate 4 mg
Prodil
Progandol (Spain)
Progandol Neo (Spain)
Prostadilat (Austria)
Tablet; Oral; Doxazosin Mesylate 2 mg
Tablet; Oral; Doxazosin Mesylate 4 mg
Prostaride (Colombia)
Prostatic (Poland)
Prostazosina (Argentina)
Prosten 1
Protectura (Greece)
Quorum (Italy)
Raporsin (United Kingdom)
Ratio-Doxazosin
Tablet; Oral; Doxazosin Mesylate 1 mg
Tablet; Oral; Doxazosin Mesylate 2 mg
Tablet; Oral; Doxazosin Mesylate 4 mg
Saidox (Italy)
Shuang Jiang Ping (China)
Slocinx (United Kingdom)
Supressin (Austria)
Tablet; Oral; Doxazosin Mesylate 2 mg
Tablet; Oral; Doxazosin Mesylate 4 mg
Tatsuzosin (Japan)
Tendura (Turkey)
Tonocardin (Bosnia & Herzegowina, Croatia (Hrvatska), Russian Federation, Slovenia)
Tablet; Oral; Doxazosin Mesylate 2 mg
Tablet; Oral; Doxazosin Mesylate 4 mg
Tonocardin SR (Slovenia)
Unoprost
Uriduct
Tablet; Oral; Doxazosin Mesylate 1 mg
Tablet; Oral; Doxazosin Mesylate 2 mg

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