Ospamox - Antibiotic of group semisynthetic penicillins a wide spectrum of action. It is a 4-hydroxyl analog of ampicillin. It has bactericidal action. Ospamox is active against aerobic gram-positive bacteria: Staphylococcus spp. (except strains producing penicillinase), Streptococcus spp; aerobic gram-negative bacteria: Neisseria Gonorrhoeae, Neisseria Meningitidis, Escherichia Coli, Shigella spp., Salmonella spp., Klebsiella spp.
Microorganisms producing penicillinase is resistant to amoxicillin.
In combination with metronidazole is active against Helicobacter Pylori. It is believed that inhibits the development of Ospamox resistance of Helicobacter pylori to metronidazole.
There is a cross-resistance between amoxycillin and ampicillin.
The spectrum of antibacterial action while expanding the application of Ospamox and beta-lactamase inhibitor clavulanic acid. This combination increased the activity of Ospamox against Bacteroides spp., Legionella spp., Nocardia spp., Pseudomonas (Burkholderia) Pseudomallei. However, Pseudomonas Aeruginosa, Serratia Marcescens, and many other gram-bacteria are resistant.
Ospamox is a moderate-spectrum antibiotic active against a wide range of Gram-positive, and a limited range of Gram-negative organisms. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other beta-lactam antibiotics. Ospamox is susceptible to degradation by β-lactamase-producing bacteria, and so may be given with clavulanic acid to increase its susceptability. The incidence of β-lactamase-producing resistant organisms, including E. coli, appears to be increasing. Ospamox is sometimes combined with clavulanic acid, a β-lactamase inhibitor, to increase the spectrum of action against Gram-negative organisms, and to overcome bacterial antibiotic resistance mediated through β-lactamase production.
Indication: For the treatment of infections of the ear, nose, and throat, the genitourinary tract, the skin and skin structure, and the lower respiratory tract due to susceptible (only b-lactamase-negative) strains of Streptococcus spp. (a- and b-hemolytic strains only), S. pneumoniae, Staphylococcus spp., H. influenzae, E. coli, P. mirabilis, or E. faecalis. Also for the treatment of acute, uncomplicated gonorrhea (ano-genital and urethral infections) due to N. gonorrhoeae (males and females).
Ospamox is an aminobenzyl penicillin that has a bactericidal action due to its inhibition of the synthesis of the bacterial cell wall. It exerts a bactericidal effect against many Gram-positive and Gram-negative microorganisms. Ospamox is not effective against beta-lactamase producing organisms.
Indications: Upper respiratory tract infections; Genito-urinary tract infections; Skin and soft tissue infections; Lower respiratory tract infections; Prophylaxis of Endocarditis - Dental Procedures; Urethritis (due to Neisseria gonorrhoeae); Lower urinary tract infections;
Ospamox is an antibiotic. It is used to treat certain bacterial infections of the ear, nose, throat, lungs, skin or bladder. Ospamox can also be used to prevent infection when you undergo certain dental procedures. Ospamox is also used in combination with other medicines for gastric ulcers caused by a type of bacteria known as Helicobacter pylori (H. pylori). Ospamox belongs to a group of antibiotics called the penicillins.
Treatment of infections due to susceptible strains of sensitive organisms: Respiratory Tract Infections: (Acute and Chronic): H. influenzae ; Streptococcus; S. pneumoniae ; Staphylococcus (nonpenicillinase-producing); E. coli (see Microbiology under Actions). Urogenital Infections (Complicated and Uncomplicated, Acute and Chronic): E. coli (see Microbiology under Actions), P. mirabilis and Strep. faecalis. Gonorrhoea: N. gonorrhoea (nonpenicillinase-producing). Skin and Skin Structure Infections: Staphylococcus (nonpenicillinase-producing); Streptococcus; E. coli (see Microbiology under Actions). Prophylaxis of Endocartitis: Amoxycillin may be used for prophylaxis of bacterial endocarditis in individuals at particular risk eg, those with a prosthetic heart valve or those who have previously had endocarditis. Infections caused by pathogens with established penicillin G susceptibility should preferentially be treated with penicillin G. Note: Therapy should be guided by bacteriological studies, including sensitivity tests and by clinical response. Amoxycillin alone or in combination with another antibiotic may be used in an emergency where the causative has not been identified.
Treatment of infections caused by amoxycillin-susceptible organisms: Respiratory Tract Infections: Upper airways and ear, nose and throat (ENT) infections; lower airways infections eg, acute and chronic bronchitis, pneumonia, lung abscesses, pertussis (incubation period and early stages). Urogenital Infections: Acute and chronic pyelonephritis, pyelitis, prostatitis, epididymitis; cystitis, urethritis, asymptomatic bacteriuria during pregnancy; gonorrhea. Gynecological infections (septic abortion, adnexitis, endometritis, etc). Gastrointestinal Infections: Typhoid fever, paratyphoid, particularly if complicated by septicemia (in combination with an oral aminoglycoside antibiotic); control of Salmonella carriers; shigellosis ; infections of the biliary system (cholangitis, cholecystitis). Skin and soft tissue infections; leptospirosis, acute and latent listeriosis. Unless parenteral treatment (eg, with ampicillin) is required, Ospamox is also active in the conditions listed as follows: Short-term (24-48 hrs) prophylactic treatment of patients undergoing surgery (eg, in the oral cavity); endocarditis eg, enterococcal endocarditis (alone or in combination with an aminoglycoside antibiotic); bacterial meningitis (pending the outcome of susceptibility tests; particularly in children); septicemias caused by amoxycillin-susceptible pathogens. Infections caused by pathogens with established penicillin G susceptibility should preferentially be treated with penicillin G.
used to treat infections in different partsof the body caused by bacteria. It is also used tostop infections when you have a tooth removed orother surgery. Amoxil may also be used incombination with other medicines to treatstomach ulcers
Ospamox is indicated in the treatment of infections due to susceptible (ONLY β-lactamase-negative) strains of the designated microorganisms in the conditions listed below:Infections of the ear, nose, and throat - due to Streptococcus spp. (α- and β-hemolytic strains only), S. pneumoniae, Staphylococcus spp., or H. influenzae. Infections of the genitourinary tract - due to E. coli, P. mirabilis, or E. faecalis. Infections of the skin and skin structure - due to Streptococcus spp. (α- and β-hemolytic strains only), Staphylococcus spp., or E. coli. Infections of the lower respiratory tract - due to Streptococcus spp. (α- and β-hemolytic strains only), S. pneumoniae, Staphylococcus spp., or H. influenzae. Gonorrhea, acute uncomplicated (ano-genital and urethral infections) - due to N. gonorrhoeae (males and females).H. pylori eradication to reduce the risk of duodenal ulcer recurrence.
Indications: Respiratory, genito-urinary, skin and soft tissue, ENT infections due to susceptible strains of Gram negative organisms like H.
influenzae, E-coli, P.
mirabilis and N.
Gram positive organisms like streptococci (including streptococcus faecalis) D.
pneumoniae and non-penicillase producing staphylococci.