Otodine consists of Chlorhexidine, Propylene Glycol.
Chlorhexidine - Antiseptic agent. Otodine (Chlorhexidine) is active against vegetative forms of gram-negative and gram-positive bacteria and yeasts, dermatophytes and lipophilic viruses. This medicine has effect for bacterial spores only at elevated temperatures. It cleans and disinfects the skin without causing damage.
Otodine (Chlorhexidine), a topical antimicrobial agent, is bactericidal. Because of its positive charge, the Otodine (Chlorhexidine) molecule reacts with the microbial cell surface to destroy the integrity of the cell membrane. This novel mechanism of action makes it highly unlikely for the development of bacterial resistance.
Mouth/Throat Oral hygiene, Gingivitis
Adult: Rinse mouth with 10 ml of a 0.2% soln for 1 minute bid-tid.
Otodine (Chlorhexidine) is a chemical antiseptic. It kills (is bactericidal to) both gram-positive and gram-negative microbes, although it is less effective with some gram-negative microbes. It is also bacteriostatic. The mechanism of action is membrane disruption, and not ATPase inactivation as previously thought. It also shows activity with enveloped viruses, though this has not been extensively investigated. Products containing Otodine (Chlorhexidine) in high concentrations must be kept away from eyes and the ears, due to the risk of damage to those organs. However, Otodine (Chlorhexidine) is safely used in very low concentrations in some contact lens solutions.
Adult: Mouth/throat Oral hygiene; Gingivitis As 0.2% soln: Rinse w/ 10 mL for 1 min 2-3 times/day.
Otodine (Chlorhexidine) Saint-Petersburg Pharmaceutical Factory is an antiseptic agent. Otodine (Chlorhexidine) is active against vegetative forms of gram-negative and gram-positive bacteria and yeasts, dermatophytes and lipophilic viruses. This medicine has effect for bacterial spores only at elevated temperatures. It cleans and disinfects the skin without causing damage.
Indications: Used in mouth wash to reduce dental plaque and bacteria, gingivitis.
Keratitis caused by Acantamoeba.
Propylene Glycol - Ketoconazole is a synthetic antifungal drug used to prevent and treat skin and fungal infections, especially in immunocompromised patients such as those with AIDS. Ketoconazole is sold commercially as an anti-dandruff shampoo, topical cream, and oral tablet, under the trademark name Nizoral by Johnson & Johnson. Ketoconazole is very lipophilic, which leads to accumulation in fatty tissues. The less toxic and more effective triazole compounds fluconazole and itraconazole have largely replaced ketoconazole for internal use. Ketoconazole is best absorbed at highly acidic levels, so antacids or other causes of decreased stomach acid levels will lower the drug's absorption when taken orally.