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Phosblock uses and description

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Phosblock - Phosblock is a phosphate binder. Phosblock helps prevent hypocalcemia (low levels of calcium in the body) caused by elevated phosphorus.

Phosblock is used to reduce blood levels of phosphorus in people with chronic kidney disease who are on dialysis.

Phosblock may also be used for purposes not listed in this medication guide.

Pharmacology: Decreases intestinal phosphate absorption by binding to phosphate in the GI tract.

Indication: Reduction of serum phosphorus in patients with chronic kidney disease who are on hemodialysis.

Unlabeled Uses

Treatment of hyperuricemia in patients undergoing hemodialysis.

Patients with end-stage renal disease (ESRD) retain phosphorus and can develop hyperphosphatemia. High serum phosphorus can precipitate serum calcium resulting in ectopic calcification. When the product of serum calcium and phosphorus concentrations (Ca x P) exceeds 55 mg, there is an increased risk that ectopic calcification will occur. Hyperphosphatemia plays a role in the development of secondary hyperparathyroidism in renal insufficiency. An increase in parathyroid hormone (PTH) levels is characteristic of patients with chronic renal failure. Increased levels of PTH can lead to osteitis fibrosa, a bone disease. A decrease in serum phosphorus may decrease serum PTH levels. Treatment of hyperphosphatemia includes reduction in dietary intake of phosphate, inhibition of intestinal phosphate absorption with phosphate binders, and removal of phosphate with dialysis. Phosblock taken with meals has been shown to decrease serum phosphorus concentrations in patients with ESRD who are on hemodialysis. In vitro studies have shown that the capsule and tablet formulations bind phosphate to a similar extent. Phosblock treatment also results in a lowering of low-density lipoprotein (LDL) and total serum cholesterol levels.

Active ingredients: Sevelamer
Unit description, dosagePrice, USD

List of phosblock brand and generic drugs

Biosev 800 mg Tablet$ 0.63
Forseal 800 mg Tablet$ 0.56
Forseal 400 mg Tablet$ 0.31
Genzyme-Renagel (Chile)
Renagel (Argentina, Australia, Austria, Belgium, Canada, Croatia (Hrvatska), Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Israel, Italy, Japan, Latvia, Luxembourg, Netherlands, New Zealand, Norway, Oman, Portugal, Romania, Serbia, Slovenia, Spain, Sweden, Switzerland, Taiwan, Turkey, United Kingdom, United States)
Capsule; Oral; Sevelamer Hydrochloride 400 mg
Tablet, Film-Coated; Oral; Sevelamer Hydrochloride 800 mg
Tablet; Oral; Sevelamer Hydrochloride 400 mg
Tablet; Oral; Sevelamer Hydrochloride 800 mg
Renagel 400 mg x 50's
Renagel 800 mg x 180's
Renagel 400 mg x 360's
Renegal (Japan)
Renvela (Germany, United States)
Tablet; Oral; Sevelamer Carbonate 800 mg
Renvela 800 mg x 180's
Renvela 800 mg x 270's
800 mg x 30's
Renvela 2.4 g x 60's
Renvela 800 mg x 30's
Renvela 800mg FC-TAB / 30
Sevelamer (Germany, United States)
Renagel 800 mg tablet$ 2.41
Renvela 800 mg tablet$ 2.17
Renagel 400 mg tablet$ 1.66
Svelam 400 mg Tablet$ 0.31
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