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Profenil uses and description
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Profenil - Profenil is a NSAID, propionic acid derivative. This medication has analgesic, anti-inflammatory and antipyretic activity. The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. A pronounced analgesic effect of ketoprofen is due to two mechanisms: peripheral (indirect, via inhibition of prostaglandin synthesis) and central (due to inhibition of prostaglandin synthesis in the central and peripheral nervous system, as well as the influence on the biological activity of other neurotrophic substances that play a key role in the release of neurotransmitters in the spinal pain brain). In addition, this drug has anti-bradykinin activity, stabilizes lysosomal membranes, causes a significant inhibition of neutrophils in patients with rheumatoid arthritis.
Profenil is a smooth muscle relaxant. Smooth muscle is a type of muscle that is not under voluntary control; it is the muscle present in places such as the gut and uterus. Profenil acts directly on the muscle in the gut, causing it to relax. This prevents the muscle spasms which occur in the gut in conditions such as irritable bowel syndrome and diverticular disease. Diverticular disease is a condition in which small pouches form in the gut lining. These pouches can trap particles of food and become inflamed and painful. In irritable bowel syndrome the normal activity of the gut muscle is lost. The muscle spasms result in symptoms such as heartburn, abdominal pain and bloating, constipation or diarrhoea. By relaxing the gut muscle, Profenil citrate relieves the symptoms of this condition. Profenil also relaxes the smooth muscle in the womb (uterus). It is therefore also used to treat painful menstruation, which is caused by muscle spasms in the uterus (dysmenorrhea).
Indication: Used to relieve cramps or spasms of the stomach and intestines. It is also useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Profenil relaxes the stomach muscles. It prevents stomach cramps in conditions like irritable bowel syndrome (also known as IBS). IBS often causes stomach pain, bloating, stomach wind, constipation or diarrhoea, swelling and pain of the large intestine. It also relaxes the muscle of the womb and is used to treat painful menstruation.
Indications: gastrointestinal spasm
Indications: musculoskeletal, joint, and soft-tissue disorders
Indications: inflammatory disorders
|Active ingredients: Alverine
|Unit description, dosage||Price, USD
|Profenil 60 mg x 100's|
|Profenil 60 mg x 500's|
List of profenil brand and generic drugs
|Akavic 40 mg x 3 Blister x 10 Tablet|
|Akavic 40 mg x 10 Blister x 10 Tablet|
|Alverine (Hungary, Singapore, Slovakia, Thailand, Turkey, Vietnam)|
|Alverine 60 mg|
|Dospasmin 40 mg x 3 Blister x 10 Tablet|
|Dospasmin 40 mg x 1 chai 200 Tablet|
|Dospasmin 40 mg x 5 Blister x 10 Tablet|
|Eftispasmin 40 mg x 3 Blister x 12 Tablet|
|Eftispasmin 40 mg x 1 chai 100 Tablet|
|Sparenil 40 mg x 3 Blister x 10 Tablet|
|Spasmaverine 40 mg x 30 Tablet|
|Tablet; Oral; Alverine Citrate|
|Spasmine (Belgium, Luxembourg)|
|Suppositories; Rectal; Hawthorn Flowers Summit Powder 80 mg; Valerian Root Dry Extract 100 mg|
|Tablet, Film-Coated; Oral; Hawthorn Flowers Summit Powder 100 mg; Valerian Root Dry Extract 120 mg|
|Spasmonal (Bahrain, Botswana, Cyprus, Hong Kong, Iraq, Ireland, Jordan, Kenya, Kuwait, Lebanon, Libya, Luxembourg, Qatar, Saudi Arabia, Singapore, Sri Lanka, Sudan, Taiwan, Uganda, United Arab Emirates, United Kingdom, Zimbabwe)|
|Capsule; Oral; Alverine Citrate 60 mg|
|Spasmonal 60 mg x 100's|
|Spasmonal 60 mg x 1000's|
|Capsule; Oral; Alverine Citrate 120 mg|