Rafonex - This medicine contains 2 types of medicines: amoxicillin and clavulanic acid. Amoxicillin is an antibiotic. It is used to treat certain bacterial infections of the ear, nose, throat, lungs, skin or bladder. Clavulanic acid improves the the antibacterial activity and effectiveness of amoxicillin.
Co-amoxiclav is the British Approved Name for the combination antibiotic containing amoxicillin trihydrate, a β-lactam antibiotic, with potassium clavulanate, a β-lactamase inhibitor. This combination results in an antibiotic with an increased spectrum of action and restored efficacy against amoxicillin-resistant bacteria that produce β-lactamase.
This name, unlike co-trimoxazole, has not been widely adopted internationally and the combination product is usually referred to by various names such as amoxicillin with clavulanic acid or amoxicillin+clavulanate or simply by a trade name such as EXCLAV (by NeoMedD), HECLAV-625 (by Mascot),Twinox (by USV) CLAMP (by FGP), Synermox, Augmentin (by GlaxoSmithKline formerly Beecham),Tormoxin Clav (India) or Clavamel.
Indications: Addition of clavulanic acid re-establishes the activity of amoxicillin against bactrias resistant to amoxicillin.
It is indicated for:Skin and soft tissue infections, intra-abdominal and gynaecologycal sepsis, urinary, billiary and respiratory tract infections, especially when empiric antibiotic therapy is nto be given for hospital acquired infections.
Gonorrhoea (including PPNG) single dose amoxicillin 3 g + clavulanic acid 0.
5 gm + probenecid 1 gm is highly curative.
Indications: Respiratory, genito-urinary, skin and soft tissue, ENT infections due to susceptible strains of Gram negative organisms like H.
influenzae, E-coli, P.
mirabilis and N.
Gram positive organisms like streptococci (including streptococcus faecalis) D.
pneumoniae and non-penicillase producing staphylococci.