SPASMO-PROXYVON - Indications: smooth muscle spasm
Dicyclomine is an anticholinergic that blocks muscarinic receptors. Dicyclomine is known as dicycloverine hydrochloride in the UK. Dicycloverine has 72 per cent of the anti-muscarinic power of atropine. It was invented in the United States in 1947.
Dicyclomine is used to treat intestinal hypermotility, the symptoms of Irritable Bowel Syndrome (IBS) (also known as spastic colon). It relieves muscle spasms and cramping in the gastrointestinal tract by blocking the activity of acetylcholine on cholinergic (or muscarinic) receptors on the surface of muscle cells. It is a smooth muscle relaxant.
In America, it is sold under the trade names: Bentyl, Byclomine, Dibent, Di-Spaz, Dilomine.
In the UK it is sold under the trade names: Merbentyl (containing 10mg dicycloverine) and Merbentyl 20 (containing 20mg dicycloverine).
It is also sold in the UK as part of a multi-ingredient preparation under the trade name Kolanticon (Peckforton Pharmaceuticals), which in addition to dicycloverine, contains an antiflatulent (simethicone) and two antacids (aluminium hydroxide and magnesium oxide).
It is sold under the trade names Bentylol (Hoechst Marion Roussel), Formulex (ICN), and Lomine (Riva) in Canada. it is sold under the trade names spasmo proxivon and spasmo plus in India.