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Simvacol

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Simvacol uses and description

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Simvacol - Simvacol is a hypolipidemic agent from a group of statins, an inhibitor of HMG-CoA reductase. This medication is a prodrug because it has in its structure the closed lactone ring which is hydrolyzed after intake.

Lipid-lowering effect of statins is associated with lower levels of total cholesterol by LDL-C. Reducing cholesterol is dose-dependent and is not linear but exponential. Statins do not affect the activity of lipoprotein and hepatic lipase, have no significant effect on the synthesis and catabolism of free fatty acids, thats why their effect on TG levels again and indirectly through their main effects on reducing LDL-C.

According to the controlled studies of Simvacol increases HDL-C to 14%.

In addition to the hypolipidemic actions Simvacol has beneficial effects in endothelial dysfunction (pre-clinical sign of early atherosclerosis), on the vascular wall, the state of atheroma, improves blood rheology, have antioxidant, antiproliferative properties. There is evidence that Simvacol improves endothelial function within 30 days of therapy.

Simvacol therapy was accompanied by a decrease in the incidence of cardiovascular disorders, regardless of baseline LDL-C.

Indications: coronary artery disease, hyperlipidaemias

Adjunct to diet for treatment of hypercholesterolaemia. Patients at high risk of CHD (w/ or w/o hypercholesterolaemia) including diabetics, those w/ history of stroke or other CV disease, peripheral vessel disease, or w/ existing CHD to reduce the risk of CV death, major CV events including stroke, & hospitalisation due to angina pectoris.

Active ingredients: Simvastatin
Unit description, dosagePrice, USD
Tablet, Film-Coated; Oral; Simvastatin 10 mg
Tablet, Film-Coated; Oral; Simvastatin 20 mg
Tablet, Film-Coated; Oral; Simvastatin 40 mg
Tablet, Film-Coated; Oral; Simvastatin 5 mg
Tablets, Film-Coated; Oral; Simvastatin 10 mg
Tablets, Film-Coated; Oral; Simvastatin 20 mg
Tablets, Film-Coated; Oral; Simvastatin 40 mg
Tablets, Film-Coated; Oral; Simvastatin 5 mg

List of simvacol brand and generic drugs

Simvaco (South Korea)
Simvacop (Denmark)
Simvacor (Bulgaria, Estonia, Germany, Greece, Israel, Latvia, Lithuania, Luxembourg, Malta, Poland, Singapore, South Africa)
Tablet; Oral; Simvastatin 10 mg
Tablet; Oral; Simvastatin 20 mg
Tablet; Oral; Simvastatin 40 mg
Tablet; Oral; Simvastatin 80 mg
Simvacor 10 mg x 10's
Simvacor 10 mg x 1000's
Simvacor 20 mg x 10's
Simvacor 20 mg x 100's
Simvacor 10 mg x 3 Blister x 10 Tablet
Simvacor 20 mg x 3 Blister x 10 Tablet
Simvacor 20 mg x 10's x 50
Simvacor 40 mg x 10's x 10 x 6
Simvacor 20 mg x 50 x 10's
Tablets, Film-Coated; Oral; Simvastatin 20 mg
Tablets; Oral; Simvastatin 10 mg
Tablets; Oral; Simvastatin 20 mg
Tablets; Oral; Simvastatin 40 mg
Tablets; Oral; Simvastatin 80 mg
Simvacor 10
Simvadoc (Germany)
Simvador
Tablet, Film-Coated; Oral; Simvastatin 10 mg
Tablet, Film-Coated; Oral; Simvastatin 20 mg
Tablet, Film-Coated; Oral; Simvastatin 40 mg
Tablets, Film-Coated; Oral; Simvastatin 10 mg
Tablets, Film-Coated; Oral; Simvastatin 20 mg
Tablets, Film-Coated; Oral; Simvastatin 40 mg
Simvadura (Germany)
Tablet, Film-Coated; Oral; Simvastatin 10 mg
Tablet, Film-Coated; Oral; Simvastatin 20 mg
Tablet, Film-Coated; Oral; Simvastatin 40 mg
Tablets, Film-Coated; Oral; Simvastatin 10 mg
Tablets, Film-Coated; Oral; Simvastatin 20 mg
Tablets, Film-Coated; Oral; Simvastatin 40 mg
Simvafar (Vietnam)
Simvafar 10 mg x 10 Blister x 10 Tablet
Simvafar 10 mg x 3 Blister x 10 Tablet
Simvafour (Belgium)
Simvagamma (Estonia, Georgia, Germany, Hungary, Latvia, Poland, Romania)
Tablet, Film-Coated; Oral; Simvastatin 10 mg
Tablet, Film-Coated; Oral; Simvastatin 20 mg
Tablet, Film-Coated; Oral; Simvastatin 40 mg
Tablet, Film-Coated; Oral; Simvastatin 5 mg
Tablets, Film-Coated; Oral; Simvastatin 10 mg

Show all Simvacol generic names
 
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