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Terbix

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Terbix uses and description

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Terbix - Pharmacology: Inhibits squalene epoxidase, resulting in ergosterol deficiency and a corresponding accumulation of squalene within the fungal cell leading to fungal cell death.

Indication: Tablets

Treatment of onychomycosis of the toenail or fingernail caused by dermatophytes.

Topical

Interdigital tinea pedis, tinea cruris, or tinea corporis caused by Epidermophyton floccosum, Trichophyton mentagrophytes, or Trichophyton rubrum.

Oral granules

Treatment of tinea capitis in patients 4 yr of age and older.

Terbix is an antifungal antibiotic.

Terbix is used to treat infections caused by fungus that affect the fingernails or toenails. Terbix oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.

Terbix may also be used for purposes not listed in this medication guide.

Terbix is an allylamine antifungal agent and acts by inhibiting squalene epoxidase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. In vitro, mammalian squalene monooxygenase (squalene 2,3-epoxidase) is only inhibited at higher (4000 fold) concentrations than is needed for inhibition of the dermatophyte enzyme. Depending on the concentration of the drug and the fungal species test in vitro, Terbix may be fungicidal. However, the clinical significance of in vitro data is unknown.

Indications: Dermatophytosis.

Terbix is an antifungal medicine. It is used to treat fungal infections of the fingernails and toenails.

Oral Dermatophytosis

Adult: 250 mg once daily for 2-4 wk in tinea cruris, 6 wk for tinea pedis, 4 wk for tinea corporis and 6-12 wk for nail infections.

Child: 10-20 kg: 62.5 mg; 20-40 kg: 125 mg; >40 kg: 250 mg. Doses to be taken once daily. Treatment is usually given for 2 wk for tinea capitis ; 2-4 wk for tinea cruris; 4 wk for tinea corporis; 6 wk in tinea pedis; 6-12 wk for nail infections. CrCl (ml/min) Dosage Recommendation <50 Half the usual oral dose. Topical/Cutaneous Dermatophytosis

Adult: Apply a 1% cream/solution once or bid. 1-2 wk to treat tinea corporis and tinea cruris; 1-wk course is for tinea pedis; 2-wk course in cutaneous candidiasis and pityriasis versicolor

Oral dermatophyte infections

Adult: 250 mg once daily for 2-4 wk in tinea cruris, 6 wk for tinea pedis, 4 wk for tinea corporis and 6-12 wk for nail infections.

Child: 10-20 kg: 62.5 mg; 20-40 kg: 125 mg; >40 kg: 250 mg. Doses to be taken once daily. Treatment is usually given for 2 wk for tinea capitis ; 2-4 wk for tinea cruris; 4 wk for tinea corporis; 6 wk in tinea pedis; 6-12 wk for nail infections. CrCl (ml/min) Dosage Recommendation <50 Half the usual oral dose. Topical/Cutaneous dermatophyte infections

Adult: Apply a 1% cream/solution once or bid. 1-2 wk to treat tinea corporis and tinea cruris; 1-wk course is for tinea pedis; 2-wk course in cutaneous candidiasis and pityriasis versicolor

Active ingredients: Terbinafine
Unit description, dosagePrice, USD
Cream; Topical; Terbinafine Hydrochloride 1%
Spray; Topical; Terbinafine Hydrochloride 1%

List of terbix brand and generic drugs

Terbital (Estonia)
Terbized CRM (India)
Terbized CRM 1% w/w CRM / 10g$ 0.87
1 % w/w x 10g$ 0.87
TERBO (India)
TERBO Cream/ Gel/ Ointment / 1(%) (10gm units)$ 0.91
Terbo 1g CRM / 10g$ 0.96
1 % x 10 g x 10g$ 0.96
Terbo Skin 10 gm Cream$ 0.96
TERBOFIN
TERBOFIN Lotion / 1(%) (15ml units)$ 1.02
TERBOFIN Capsule/ Tablet / 250mg (7 units)$ 3.37
TERBOFIN Cream/ Gel/ Ointment / 1(%) (10gm units)$ 0.83
Terbofin Skin 10 gm Cream$ 1.02
Terbofin 250 mg Tablet$ 0.48
Terbofin 15 ml Lotion$ 1.15
Terbonile (Turkey)
Terby (Japan)
Tercyd (Tunisia)
Terekol (Argentina)
Terfalin (Georgia)
TERFAST (India)
TERFAST Capsule/ Tablet / 250mg (7 units)$ 1.67
250 mg x 7's$ 1.67
Terfast 250 mg Tablet$ 0.21
Terfast 250mg TAB / 7$ 1.67
Terfex (Chile, Ecuador, Peru, Venezuela)
Cream; Topical; Terbinafine Hydrochloride 1%
Spray; Topical; Terbinafine Hydrochloride 1%
Tablet; Oral; Terbinafine Hydrochloride 250 mg
Tablets; Oral; Terbinafine Hydrochloride 250 mg
Terfex 100+4+2.5 Tablet$ 0.03
Terfimed (Czech Republic)
Terfin (Argentina, Hungary, Indonesia)
Tablet; Oral; Terbinafine Hydrochloride 250 mg
Terfin 60 mg x 50's$ 2.58
Tablets; Oral; Terbinafine Hydrochloride 250 mg
Terfina (Oman)
Terfine (Taiwan)
Terfine 250 mg x 30's
Terfine Cream (Taiwan)
Terfine Cream 1 % x 10 g
Terfine Cream 1 % x 20 g
Terfinil (Greece)
Terfinor (Greece)
Terfung (Taiwan)
Terfung 250 mg x 1000's
TERIF (India)
250 mg x 7's$ 4.81
Terif 250 mg Tablet$ 0.69
Terif 250mg TAB / 7$ 4.81
Termicon (Russian Federation)
Cream; Topical; Terbinafine Hydrochloride 1%

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