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Trixifen

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Trixifen uses and description

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Trixifen - Trixifen is an anti-psychotic medication in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). It works by changing the actions of chemicals in your brain.

Trixifen is used to treat psychotic disorders such as schizophrenia.

Trixifen is usually given after other medications have been tried without successful treatment of schizophrenia.

Trixifen may also be used for purposes not listed in this medication guide.

Used for: Treating schizophrenia in patients who have not shown improvement with or are unable to take other medicines. It may also be used for other conditions as determined by your doctor.

Trixifen is a phenothiazine. It is not known exactly how it works.

Trixifen is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Trixifen has not been shown effective in the management of behaviorial complications in patients with mental retardation.

Oral Schizophrenia

Adult: Initially, 50-100 tid daily and slowly titrated upwards at no more than 100 mg wkly. Max: 800 mg daily in 2-4 divided doses.

Child: 2-12 yr: Initially, 0.5 mg/kg daily in divided doses, increased gradually until optimum effect obtained. Max: 3 mg/kg daily. Renal impairment: Lower initial doses and more gradual dosage increase. Hepatic impairment: Lower initial doses and more gradual dosage increase. Oral Depression

Adult: Initially, 25 mg tid, titrated to 20-200 mg daily. Renal impairment: Lower initial doses and more gradual dosage increase. Hepatic impairment: Lower initial doses and more gradual dosage increase. Incompatibility: Oral liquid Trixifen should not be admin simultaneously with carbamazepine oral suspension.

Trixifen (Mellaril, Novoridazine, Thioril) is a piperidine antipsychotic drug belonging to the phenothiazine drug group and was previously widely used in the treatment of schizophrenia and psychosis. Due to concerns about cardiotoxicity and retinopathy at high doses this drug is not commonly prescribed, reserved for patients who have failed to respond to, or have contraindications for, more widely used antipsychotics. A serious side effect is the potentially fatal neuroleptic malignant syndrome. It exerts its actions through a central adrenergic-blocking, a dopamine-blocking and minor anticholinergic activity.

In older references, it is sometimes described as atypical, but more recently it is usually described as typical, with the term "atypical" usually reserved for agents showing D4 selectivity or serotonin antagonism.

Oral Schizophrenia

Adult: Initially, 50-100 tid daily and slowly titrated upwards at no more than 100 mg wkly. Max: 800 mg daily in 2-4 divided doses.

Child: 2–12 yr: Initially, 0.5 mg/kg daily in divided doses, increased gradually until optimum effect obtained. Max: 3 mg/kg daily. Renal impairment: Lower initial doses and more gradual dosage increase. Hepatic impairment: Lower initial doses and more gradual dosage increase. Oral Depression

Adult: Initially, 25 mg tid, titrated to 20–200 mg daily. Renal impairment: Lower initial doses and more gradual dosage increase. Hepatic impairment: Lower initial doses and more gradual dosage increase. Incompatibility: Oral liquid Trixifen should not be admin simultaneously with carbamazepine oral suspension.

Indications:

Adult: PO Schizophrenia Initial: 50-100 3 times/day, increase slowly if needed. Max: 800 mg/day in 2-4 divided doses. Depression Initial: 25 mg 3 times/day.

Maintenance: 20-200 mg/day.

All types of acute and chronic schizophrenia, including those which did not respond to the usual neuroleptics; manic syndromes.

Active ingredients: Thioridazine
Unit description, dosagePrice, USD

List of trixifen brand and generic drugs

Thioril (India, Russian Federation)
100 mg x 10's$ 1.07
Thioril 25mg TAB / 10$ 0.31
Thioril 50mg TAB / 10$ 0.60
Thioril 100mg TAB / 10
Thioril 50 mg Tablet$ 0.08
Thioril 10 mg Tablet$ 0.02
Thioril 25 mg Tablet$ 0.04
Thioril 100 mg Tablet$ 0.11
Thiorizil (Vietnam)
Thiorizil 100 mg x 10 Blister x 10 Tablet
Thiosia (Thailand)
Thiosia 10 mg x 1,000's$ 16.67
Thiosia 25 mg x 1,000's$ 25.00
Thiozid (India)
Thiozid 10mg TAB / 10$ 0.18
Thiozid 25mg TAB / 10$ 0.35
Thiozid 50mg TAB / 10$ 0.69
10 mg x 10's$ 0.18
25 mg x 10's$ 0.35
50 mg x 10's$ 0.69
Thiozid 50 mg Tablet$ 0.07
Thiozid 25 mg Tablet$ 0.04
Thiozid 10 mg Tablet$ 0.02
Thiozine (Philippines)
Thiozine -10 10 mg x 100's
Thiozine -25 25 mg x 100's
Thoraplan
Thoraplan 25 mg Tablet$ 0.05
Thoraplan 50 mg Tablet$ 0.09
Tinsenol
Tioridazin
Tioridazina Clorhidrato (Chile)
Tioridazina L.CH. (Chile)
Tioridazina Sanitas (Chile)
ZENERIL (India)
10 mg x 10's$ 0.18
25 mg x 10's$ 0.32
50 mg x 10's$ 0.63
Zeneril 10mg TAB / 10$ 0.18
Zeneril 25mg TAB / 10$ 0.32
Zeneril 50mg TAB / 10$ 0.63
Zeneril 10 mg Tablet$ 0.02
Zeneril 100 mg Tablet$ 0.11
Zeneril 50 mg Tablet$ 0.07
Zeneril 25 mg Tablet$ 0.03
Zina
Zina 25 mg Tablet$ 0.06
Zina 50 mg Tablet$ 0.10

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