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Valdyne

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Valdyne uses and description

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Valdyne - Pharmacology: Reduces inflammation, fever, and pain by inhibiting prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2) isoenzyme.

Indication: Relief of signs and symptoms of osteoarthritis (OA), rheumatoid arthritis (RA) in adults, and ankylosing spondylitis; management of acute pain in adults; treatment of primary dysmenorrhea; reduction of the number of adenomatous colorectal polyps in familial adenomatous polyposis (FAP), as an adjunct to usual care; relief of signs and symptoms of juvenile RA (JRA) in patients 2 yr of age and older.

Unlabeled Uses

Adjunctive therapy in the treatment of schizophrenia (inconclusive data); prevention of colorectal cancer; preterm labor.

Used for: Treating rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis, menstrual pain, or pain. It may also be used for other conditions as determined by your doctor.

Valdyne is a COX-2 inhibitor NSAID. It works by blocking certain substances in the body that cause inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

Valdyne, a selective cyclooxygenase-2 (COX-2) inhibitor, is classified as a nonsteroidal anti-inflammatory drug (NSAID). Valdyne is used to treat rheumatoid arthritis, osteoarthritis, and familial adenomatous polyposis (FAP). Because of its lack of platelet effects, Valdyne is not a substitute for aspirin for cardiovascular prophylaxis. It is not known if there are any effects of Valdyne on platelets that may contribute to the increased risk of serious cardiovascular thrombotic adverse events associated with the use of celecoxib. Inhibition of PGE2 synthesis may lead to sodium and water retention through increased reabsorption in the renal medullary thick ascending loop of Henle and perhaps other segments of the distal nephron. In the collecting ducts, PGE2 appears to inhibit water reabsorption by counteracting the action of antidiuretic hormone.

Valdyne helps relieve pain and inflammation. It may also be used to provide relief in Osteoarthritis (OA) or Rheumatoid Arthritis (RA). Valdyne may also be used to treat a colon disease known as Familial Adenomatous Polyposis. (FAP).

Oral Osteoarthritis

Adult: 200 mg as a single dose or in 2 divided doses. May increase to 200 mg 2 times if necessary. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Rheumatoid arthritis

Adult: 100-200 mg bid.

Elderly: 100 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Dysmenorrhoea

Adult: Initially, 400 mg followed by 200 mg if necessary on the 1 st day.

Maintenance: 200 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Pain relief

Adult: Initially, 400 mg followed by 200 mg if necessary on the 1 st day.

Maintenance: 200 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Familial adenomatous polyposis

Adult: 400 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use.

Oral Osteoarthritis

Adult: 200 mg as a single dose or in 2 divided doses. May increase to 200 mg bid if necessary. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Rheumatoid arthritis

Adult: 100-200 mg bid.

Elderly: 100 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Dysmenorrhoea

Adult: Initially, 400 mg followed by 200 mg if necessary on the 1 st day.

Maintenance: 200 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Pain

Adult: Initially, 400 mg followed by 200 mg if necessary on the 1 st day.

Maintenance: 200 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Familial adenomatous polyposis

Adult: 400 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use.

Indications:

Adult: PO Osteoarthritis 200 mg 1-2 times/day. May increase to 200 mg twice daily if needed. Rheumatoid arthritis 100-200 mg twice daily. Pain relief; Dysmenorrhoea Initial: 400 mg followed by 200 mg on the 1st day if needed.

Maintenance: 200 mg twice daily. Familial adenomatous polyposis 400 mg twice daily.

Oral Osteoarthritis

Adult: 200 mg as a single dose or in 2 divided doses. May increase to 200 mg 2 times if necessary. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Rheumatoid arthritis

Adult: 100-200 mg bid.

Elderly: 100 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Dysmenorrhoea

Adult: Initially, 400 mg followed by 200 mg if necessary on the 1 st day.

Maintenance: 200 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Pain relief

Adult: Initially, 400 mg followed by 200 mg if necessary on the 1 st day.

Maintenance: 200 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Oral Familial adenomatous polyposis

Adult: 400 mg bid. Hepatic impairment: Child-Pugh category B: Reduce dose by 50%. Child-Pugh category C: Avoid use. Special Populations: Reduce dose to 50% in patients with moderate hepatic impairment.

Relief of signs and symptoms of osteoarthritis (OA), rheumatoid arthritis (RA) in adults, and ankylosing spondylitis; management of acute pain in adults; treatment of primary dysmenorrhea; reduction of the number of adenomatous colorectal polyps in familial adenomatous polyposis (FAP), as an adjunct to usual care; relief of signs and symptoms of juvenile RA (JRA) in patients 2 yr of age and older. Unlabeled UsesAdjunctive therapy in the treatment of schizophrenia (inconclusive data); prevention of colorectal cancer; preterm labor.

Indications:

Adult: PO Osteoarthritis 200 mg 1-2 times/day. May increase to 200 mg 2 times daily if needed. Rheumatoid arthritis 100-200 mg 2 times daily. Pain relief; Dysmenorrhea Initial: 400 mg followed by 200 mg on the 1st day if needed.

Maintenance: 200 mg 2 times daily. Familial adenomatous polyposis 400 mg 2 times daily.

Active ingredients: Celecoxib
Unit description, dosagePrice, USD

List of valdyne brand and generic drugs

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Rheumac 100 mg x 2 Blister x 10 Tablet
Rheumac 200 mg x 2 Blister x 10 Tablet
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Secnipro 100 mg x 2 Blister x 10 Tablet
Secnipro 200 mg x 2 Blister x 10 Tablet
Selecap (Vietnam)
Selecap 200 mg x 2 Blister x 10 Tablet
Selecox (Bangladesh)
Sionara (Myanmar)
SIONARA Capsule/ Tablet / 200mg (10 units)$ 1.30
SIONARA Capsule/ Tablet / 100mg (10 units)$ 0.74
100 mg x 10's$ 0.74
200 mg x 10's$ 1.30
Sionara 100mg CAP / 10$ 0.74
Sionara 200mg CAP / 10$ 1.30
Sionara 100 mg Capsule$ 0.07
Sionara 200 mg Capsule$ 0.13
Solexa (Luxembourg, Portugal)
Speshel
Speshel 200 mg Capsule$ 0.13
Speshel 100 mg Capsule$ 0.07
Thritex (Peru)
Tisorek
Ultracele
Xalenco (Vietnam)
Xalenco 200 mg x 3 Blister x 10 Tablet
ZECOXIB (India)
ZECOXIB Capsule/ Tablet / 200mg (10 units)$ 0.74
ZECOXIB Capsule/ Tablet / 100mg (10 units)$ 0.37
Zecoxib 100mg CAP / 50$ 1.94
Zecoxib 200mg CAP / 50$ 3.86
100 mg x 50's$ 1.94
200 mg x 50's$ 3.86
Zecoxib 200 mg Capsule$ 0.08
Zecoxib 100 mg Capsule$ 0.04
Zycel (India, Myanmar, Sri Lanka)
ZYCEL Capsule/ Tablet / 100mg (10 units)$ 1.05
ZYCEL Capsule/ Tablet / 200mg (10 units)$ 1.85
100 mg x 10's$ 1.02
200 mg x 10's$ 1.79
Zycel 100mg CAP / 10$ 1.02
Zycel 200mg CAP / 10$ 1.79
Capsules; Oral; Celecoxib 100 mg
Capsules; Oral; Celecoxib 200 mg
Zycel 200 mg Capsule$ 0.18
Zycel 100 mg Capsule$ 0.10
Zycel 100/Zycel 200 (Vietnam)
Zycel 100/Zycel 200 100 mg x 10 Blister x 10 Tablet
Zycel 100/Zycel 200 200 mg x 10 Blister x 10 Tablet

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