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ZOREX-ER

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ZOREX-ER uses and description

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ZOREX-ER - Divalproex is a stable co-ordination compound comprised of sodium valproate and valproic acid in a 1:1 molar relationship and formed during the partial neutralization of valproic acid with 0.5 equivalent of sodium hydroxide. Divalproex is an anticonvulsant and mood-stabilizing drug used primarily in the treatment of epilepsy and bipolar disorder. It is also used to treat migraine headaches and schizophrenia. In epileptics, divalproex is used to control absence seizures, tonic-clonic seizures (grand mal), complex partial seizures, and the seizures associated with Lennox-Gastaut syndrome. Divalproex is believed to affect the function of the neurotransmitter GABA (as a GABA transaminase inhibitor) in the human brain. Divalproex dissociates to the valproate ion in the gastrointestinal tract.

Oral Primary generalised seizures

Adult: Initially, 10-15 mg/kg/day in 2-4 divided doses, if necessary, increase at 5-10 mg/kg/wk. Max: 60 mg/kg/day.

Child: ≥10 yr: Initially, 10-15 mg/kg/day in 2-4 divided doses, if necessary, increase at 5-10 mg/kg/wk. Max: 60 mg/kg/day. Oral Partial seizures

Adult: Initially, 10-15 mg/kg/day in 2-4 divided doses, if necessary, increase at 5-10 mg/kg/wk. Max: 60 mg/kg/day.

Child: ≥10 yr: Initially, 10-15 mg/kg/day in 2-4 divided doses, if necessary, increase at 5-10 mg/kg/wk. Max: 60 mg/kg/day. Oral Acute manic episodes of bipolar disorder

Adult: Initially, 25 mg/kg once daily, may increase rapidly to achieve optimal response at the lowest therapeutic dose. Max: 60 mg/kg/day. Oral Prophylaxis of migraine

Adult: 500 mg once daily for 1 wk, may increase to 1000 mg once daily.

Indications:

Adult: PO Partial seizures; Primary generalised seizures Initial: 10-15 mg/kg/day in 2-4 divided doses. Max: 60 mg/kg/day. Acute manic episodes of bipolar disorder Initial: 25 mg/kg once daily. Max: 60 mg/kg/day. MIgraine prophylaxis 500 mg once daily for 1 wk, up to 1,000 mg once daily.

Oral Primary generalised seizures e.g. absence and myoclonic seizures

Adult: Initially, 10-15 mg/kg/day in 2-4 divided doses, if necessary, increase at 5-10 mg/kg/wk. Max: 60 mg/kg/day.

Child: ≥10 yr: Initially, 10-15 mg/kg/day in 2-4 divided doses, if necessary, increase at 5-10 mg/kg/wk. Max: 60 mg/kg/day. Oral Partial seizures

Adult: Initially, 10-15 mg/kg/day in 2-4 divided doses, if necessary, increase at 5-10 mg/kg/wk. Max: 60 mg/kg/day.

Child: ≥10 yr: Initially, 10-15 mg/kg/day in 2-4 divided doses, if necessary, increase at 5-10 mg/kg/wk. Max: 60 mg/kg/day. Oral Acute manic episodes of bipolar disorder

Adult: Initially, 25 mg/kg once daily, may increase rapidly to achieve optimal response at the lowest therapeutic dose. Max: 60 mg/kg/day. Oral Migraine prophylaxis

Adult: 500 mg once daily for 1 wk, may increase to 1000 mg once daily.

Active ingredients: divalproex sodium
Unit description, dosagePrice, USD
250 mg x 10's$ 0.68
500 mg x 10's$ 1.27

List of zorex-er brand and generic drugs

Valp-ER (India)
250 mg x 100's$ 0.90
500 mg x 60's$ 0.84
Valpret CR
Valpret CR 500 mg Tablet$ 0.13
Valpret CR 200 mg Tablet$ 0.05
Valpret CR 300 mg Tablet$ 0.08
Valpret-CR (India)
Valpret-CR 200mg TAB / 20$ 1.09
Valpret-CR 300mg TAB / 20$ 1.52
Valpret-CR 500mg TAB / 10$ 1.30
200 mg x 20's$ 1.09
300 mg x 20's$ 1.52
500 mg x 10's$ 1.30
Valprid-CR (India)
Valprid-CR Na valproate 500mg,ValproicAcid 217.5mg FC-TAB / 10$ 1.71
Valprid-CR Na valproate 133.5mg,ValproicAcid 58mg FC-TAB / 10$ 0.62
Valprid-CR Na valproate 200mg,ValproicAcid 87mg FC-TAB / 10$ 0.92
Valprid-CR Na valproate 333mg,ValproicAcid 145mg FC-TAB / 10$ 1.52
10's$ 1.71
Valprid-CR Na valproate 500mg, ValproicAcid 217.5mg FC-TAB / 10$ 1.71
Valprid-CR Na valproate 133.5mg, ValproicAcid 58mg FC-TAB / 10$ 0.62
Valprid-CR Na valproate 200mg, ValproicAcid 87mg FC-TAB / 10$ 0.92
Valprid-CR Na valproate 333mg, ValproicAcid 145mg FC-TAB / 10$ 1.52
Valprol-CR (India)
Valprol-CR 200mg TAB / 10$ 0.45
Valprol-CR 300mg TAB / 10$ 0.54
Valprol-CR 500mg TAB / 10$ 0.83
Valprol-CR 200mg SYR / 100ml$ 0.58
200 mg x 10's$ 0.45
300 mg x 10's$ 0.54
500 mg x 10's$ 0.83
Valpromax (India)
Valpromax Na Valproate 200mg, ValproicAcid 87mg TAB / 10$ 1.02
10's$ 1.02
Valpromax 200+87 Tablet$ 0.10
Valpromax-DS (India)
Valpromax-DS Na Valproate 333mg, ValproicAcid 145mg TAB / 10$ 3.52
10's$ 3.52
Zorat CR
Zorat CR Na valproate 134mg,ValproicAcid 58mg TAB / 100$ 0.57
Zorat CR 200+87 Tablet$ 0.08
Zorat CR 333+153 Tablet$ 0.11
Zorat CR 134+58 Tablet$ 0.06
Zorat CR 500
Zorat CR 500 Na valproate 333mg,ValproicAcid 153mg TAB / 100$ 1.19
Zorat-CR (India)
Zorat-CR Na Valproate 134mg, ValproicAcid 58mg TAB / 10$ 0.57
Zorat-CR Na Valproate 200mg, ValproicAcid 87mg TAB / 10$ 0.81
Zorat-CR Na Valproate 333mg, ValproicAcid 153mg TAB / 10$ 1.15
10's$ 1.15

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