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Zenalb 20

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Zenalb 20 uses and description

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Zenalb 20 - Intravenous Acute hypovolaemic shock

Adult: Initially, 25 g of albumin, adjusted according to patient's response. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution).

Child: Up to 1 g/kg, adjusted according to patient's response. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). Intravenous Hypoproteinaemia

Adult: Up to 2 g/kg daily. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). Intravenous Neonatal hyperbilirubinaemia

Child: 1 g/kg of albumin before exchange transfusion. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). Incompatibility: Dilution with water will produce a hypo-osmolar solution that may cause severe haemolysis and renal failure. Y-site admin: Midazolam, vancomycin, verapamil. Admixture: Verapamil.

Human serum albumin is the most abundant protein in human blood plasma. It is produced in the liver. Albumin comprises about half of the blood serum protein. It is soluble and monomeric.

The gene for albumin is located on chromosome 4 and mutations in this gene can result in various anomalous proteins. The Zenalb 20 gene is 16,961 nucleotides long from the putative 'cap' site to the first poly(A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain.

Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.

The reference range for albumin concentrations in blood is 30 to 50 g/L. It has a serum half-life of approximately 20 days. It has a molecular mass of 67 kDa.

Intravenous Acute hypovolaemic shock

Adult: Initially, 25 g of albumin, adjusted according to patient's response. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution).

Child: Up to 1 g/kg, adjusted according to patient's response. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). Intravenous Hypoproteinaemia

Adult: Up to 2 g/kg daily. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). Intravenous Neonatal hyperbilirubinaemia

Child: 1 g/kg of albumin before exchange transfusion. Usual rates of infusion: Up to 5 ml/minute (5% solution) or 1-2 ml/minute (20% solution). Special Populations: Volume admin and rate of infusion must always be individualised according to situation and response. Usual rates of infusion are up to 5 ml/min (5% soln) or 1-2 ml/min (20% soln). Incompatibility: Dilution with water will produce a hypo-osmolar solution that may cause severe haemolysis and renal failure. Y-site admin: Midazolam, vancomycin, verapamil. Admixture: Verapamil.


Indications: Hypoproteinaemia.

Hypovolaemic shock.

Burns.

Used in exchange transfusion in neonatal jaundice.

Active ingredients: Human albumin
Unit description, dosagePrice, USD
Zenalb 20 20 % x 50 mL x 1's$ 69.87
Zenalb 20 20 % x 100 mL x 1's$ 141.27
Zenalb 20 20 % x 50 mL
Zenalb 20 20 % x 1 loï 50 mL

List of zenalb 20 brand and generic drugs

Human Albumin Biotest 20% (United Kingdom)
Human Albumin Biotest 5% (United Kingdom)
Human Albumin Octapharma (Thailand)
Human Albumin Octapharma 20 % x 50 mL
Human Albumin Octapharma 25 % x 50 mL
HUMIN (India)
HUMIN Injection / 0.2 (100ml units)$ 75.87
20 % x 100ml$ 75.87
Humin 20% VIAL / 100ml$ 75.87
Intravenous Solution
Intravenous Solution Infusion / 5(%) (50ml units)$ 18.48
Intravenous Solution Infusion / 0.2 (100ml units)$ 82.41
Intravenous Solution Infusion / 0.2 (50ml units)$ 44.93
Intravenous Solution Infusion / 5(%) (250ml units)$ 63.20
Kedrialb (Philippines)
Kedrialb (vial) 20 % x 50 mL$ 87.50
NSA Injection (Singapore)
NSA Injection 20 % x 1's
Pacliall
Pacliall Paclitaxel 100 mg, albumin 900mg. INJ / 20ml$ 166.67
Pacliall 100mg INJ / 1$ 166.67
Plasbumin 25% Infusion (Hongkong)
Plasbumin 25% (Albumin, Human) Infusion 25 % x 20 mL$ 240.00
Plasbumin 25% (Albumin, Human) Infusion 25 % x 50 mL
Plasbumin-20 (Indonesia)
Plasbumin-20 20 % x 50 mL x 1's$ 69.49
Plasbumin-20 20 % x 100 mL x 1's$ 138.97
Plasbumin-25 (Indonesia)
Plasbumin-25 25 % x 20 mL x 1's$ 34.48
Plasbumin-25 25 % x 50 mL x 1's$ 80.84
Plasbumin-25 25 % x 100 mL x 1's$ 161.67
Plasbumin-5 (Indonesia)
Plasbumin-5 5 % x 50 mL x 1's$ 30.60
Plasbumin-5 5 % x 250 mL x 1's$ 106.08
Plasbutein (Philippines)
Plasbutein 20 % x 50 mL
Plasbutein 20 % x 100 mL
Robumin (Indonesia)
Robumin 20 % x 50 mL x 1's$ 59.16
Robumin 20 % x 100 mL x 1's$ 112.20
Robumin 25 % x 50 mL x 1's$ 72.42
Sll Human Albumin
Sll Human Albumin 100 ml Infusion$ 5.10
VOLUMIN (India)
VOLUMIN Injection / 0.2 (100ml units)$ 73.89
Volumin 20% INF / 100ml$ 73.89
20 % x 100ml$ 73.89
Volumin 100 ml Infusion$ 0.06
ZY-ALBUMIN (India)
25 %
Zy-Albumin 25% INJ
Zy. Albumin (IV)
Zy. Albumin (IV) 25% INJ
 
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